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A prospective randomized comparison of diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy

Prostate Cancer and Prostatic Diseases volume 11, pages 134–138 (2008)Cite this article

Abstract

The aim of this study is to elucidate the diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy for prostate cancer. We prospectively randomized 200 consecutive men into two groups to undergo systematic prostate biopsy. Overall positivity for cancer was similar (47% by transperineal and 53% by transrectal; P=0.480). However, in case with ‘gray zone’ PSA (from 4.1 to 10.0 ng/ml), significantly more cores were positive when approach was transperineal, especially among transition zone cores. Therefore, urologist preferences are sufficient for choosing an approach, except for a possible small advantage of transperineal biopsy when PSA is in gray zone.

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Authors and Affiliations

  1. Division of Urology, Department of Organ Therapeutics, Kobe University Graduate School of Medicine, Kobe, Japan

    A Takenaka, T Ishimura & M Fujisawa

  2. Department of Urology, Kawasaki Medical School, Kurashiki, Japan

    R Hara, T Fujii, Y Jo & A Nagai

Authors
  1. A Takenaka
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  2. R Hara
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  3. T Ishimura
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  4. T Fujii
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  5. Y Jo
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  6. A Nagai
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  7. M Fujisawa
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Correspondence to A Takenaka.

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Takenaka, A., Hara, R., Ishimura, T. et al. A prospective randomized comparison of diagnostic efficacy between transperineal and transrectal 12-core prostate biopsy. Prostate Cancer Prostatic Dis 11, 134–138 (2008). https://doi.org/10.1038/sj.pcan.4500985

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  • DOI: https://doi.org/10.1038/sj.pcan.4500985

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