Issue 23, 2016

Novel BODIPY-based Ru(ii) and Ir(iii) metalla-rectangles: cellular localization of compounds and their antiproliferative activities

Abstract

The first examples of Ru(ii) and Ir(iii) metalla-rectangles [1]4+–[4]4+ containing a BODIPY-based linker are reported; some of these compounds exhibited highly selective anticancer activity and interact strongly with DNA as well as protein. The characteristic green fluorescence of a BODIPY ligand and associated aggregation-induced emission (AIE) permitted visualization of compounds inside the cells using confocal microscopy.

Graphical abstract: Novel BODIPY-based Ru(ii) and Ir(iii) metalla-rectangles: cellular localization of compounds and their antiproliferative activities

Supplementary files

Article information

Article type
Communication
Submitted
05 Jan 2016
Accepted
20 Jan 2016
First published
20 Jan 2016

Chem. Commun., 2016,52, 4274-4277

Novel BODIPY-based Ru(II) and Ir(III) metalla-rectangles: cellular localization of compounds and their antiproliferative activities

G. Gupta, A. Das, N. B. Ghate, T. Kim, J. Y. Ryu, J. Lee, N. Mandal and C. Y. Lee, Chem. Commun., 2016, 52, 4274 DOI: 10.1039/C6CC00046K

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