Original ArticlesMetastases to breast simulating ductal carcinoma in situ: Report of two cases and review of the literature
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Metastatic nonhematopoietic neoplasms to the breast: a study of 238 cases
2022, Human PathologyCitation Excerpt :Histomorphology plays one of the key roles in differentiating primary vs. metastatic lesion. The presence of in situ carcinoma favors primary lesion; however, some metastatic neoplasms, particularly, metastatic NENs can mimic in situ carcinoma [18,26,27]. Other diagnostic clues include unusual morphology, well-circumscribed borders, lack of desmoplastic reaction, and extensive lymphovascular involvement [7,22,23,28].
Merkel cell carcinoma, melanoma, metastatic mimics of breast cancer
2017, Seminars in Diagnostic PathologyCitation Excerpt :The presence of DCIS is generally regarded as good evidence of primary breast origin.29,30,34,42,47,75 Nevertheless, several case reports have documented examples of metastatic neoplasms ‘colonizing’ existing ductal or lobular structures, or large intralymphatic deposits mimicking an in situ component.32,42,79,80 Incidental DCIS or LCIS may lie adjacent to the metastasis, but in this case the cytologic features of the in situ and invasive components should differ.42
Diagnostic Pathology: Breast
2017, Diagnostic Pathology: BreastIntramammary metastasis of renal cell carcinoma: A diagnostic trap
2016, Gynecologie Obstetrique et FertiliteA case of renal cell carcinoma metastasizing to invasive ductal breast carcinoma
2014, Journal of the Formosan Medical AssociationCitation Excerpt :Although the present patient's history of clear cell RCC and the striking dimorphic features prompted accurate diagnosis in our case, diagnostic problems do exist in metastatic neoplasms involving otherwise normal breast tissue. There have been several reported cases initially diagnosed as primary breast tumors that were later shown to be metastatic neoplasms from extramammary origins such as clear cell RCC,10 papillary RCC, and ovarian serous adenocarcinoma.11 No reliable clinical features distinguish a metastatic breast lesion from primary breast cancer.8
Metastases to and from the Breast
2012, Surgical Pathology Clinics