Regular Article
Treatment of genital Chlamydia trachomatis infection in pregnancy

https://doi.org/10.1053/beog.2002.0338Get rights and content

Abstract

This chapter gives a systematic review of the literature on treatment of Chlamydia trachomatis infections in pregnant women. The benefits of timely treatment of chlamydial infections in pregnant women are discussed. Antibiotic regimens commonly used for this purpose are identified. A meta-analysis based on randomized trials on pregnant women was performed to compare various antibiotic regimes in terms of microbiological cure, side-effects and tolerance. Data on safety related to the use of these antibiotics during pregnancy are summarized. Cost-effectiveness analyses on relevant antibiotic regimes for the treatment of uncomplicated chlamydial infection in women are identified. Their relevance and their shortcomings regarding the obstetric population are discussed. Treatment options for those who failed initial antibiotic treatment, as well as for the sexual partners of infected patients, are mentioned.

References (31)

  • MR Hammersclag

    Chlamydial infections in infants and children

  • I Cohen et al.

    Improved pregnancy outcome following successful treatment of chlamydial infection

    Journal of the American Medical Association

    (1990)
  • J Schachter et al.

    Experience with the routine use of erythromycin for chlamydial infections in pregnancy

    New England Journal of Medicine

    (1986)

  • Morbidity and Mortality Weekly Reports

    (2002)
  • AH Magat et al.

    Double-blind randomized study comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy

    Obstetrics and Gynecology

    (1993)
    • View full text
    Copyright © 2002 Elsevier Science Ltd. All rights reserved.