Original investigationsDialysis therapiesHypertension in pediatric patients on long-term dialysis: A report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)
Section snippets
Methods
Data were obtained from the dialysis NAPRTCS database, which collects status information at the time of initiation of maintenance dialysis therapy (first 30 days of dialysis) and every 6 months thereafter. All data received for patients initiating dialysis therapy after January 1, 1992, through February 2004 were included in the analysis. The study cohort included 3,743 patients aged between 0 and 21 years. Data obtained at baseline included age, sex, race, primary renal diagnosis, dialysis
Results
At baseline, in the cohort of 3,743 children, the majority were male (55%) and white (48%); 24% were African American and 21% were Hispanic. Primary kidney diagnoses included structural anomalies/familial diseases (39%), glomerulonephritis/focal segmental glomerulosclerosis, systemic immunologic disease (30%), and others (31%). For 10% of children, baseline body mass index was at the 95th percentile or greater. The majority of patients (67.5%) entered peritoneal dialysis as renal replacement
Discussion
This retrospective analysis of pediatric patients from the large dialysis NAPRTCS database is the first pediatric study to report longitudinal changes in BP in children on maintenance dialysis therapy. There are very few studies evaluating BP during long-term dialysis therapy in children. One reason is that the majority of pediatric patients undergo kidney transplantation within the first year after entering dialysis therapy. Another reason is the difficulty of interpreting BP because of the
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Originally published online as doi:10.1053/j.ajkd.2004.11.006 on December 29, 2004.
The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) is a voluntary collaborative effort comprising more than 140 pediatric renal disease treatment centers in the United States, Canada, Mexico, and Costa Rica.