Clinical–alimentary tractMucosal Healing in Inflammatory Bowel Disease: Results From a Norwegian Population-Based Cohort
Section snippets
Study Population
The present population-based cohort of 843 incident cases of IBD in Norway was collected from 1990 to 19945 and subjected to a scheduled prospective follow-up, with a 1-year visit and a 5-year visit. The cohort was established during collaboration among 15 hospitals and 1236 general practitioners. The patients were treated on an individual basis between the scheduled visits at the hospital. These visits took place at baseline, when the diagnosis was established and treatment started, and at the
Results
Information on a total of 513 incident UC patients was available from the Inflammatory Bowel disease in SouthEastern Norway (IBSEN) study. After exclusion of patients undergoing colectomy during the first year after diagnosis (n = 15), and those who did not meet within the time limits for the 1-year visit (n = 50), 448 UC patients were eligible for the 1-year follow-up. Of these, 94 were not examined by colonoscopy for different reasons (Table 1). The first year relapse frequency in patients
Summary
The present study shows that the prediction of MH based on characteristics of patients is complex. It was, however, possible to identify risk factors for inflammatory activity after 1 year of individual treatment. The results were mostly based on multiple logistic regression analyses, but univariate significant associations were also noted. Additionally, indications on the predictive value of established MH after 1 year of treatment for the subsequent outcome of disease were found.
In UC, MH at
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Cited by (0)
Supported partially by CENTOCOR INC. for the IBSEN study.
There is no conflict of interest for any of the authors.