Treatment of pseudotumors with nonsteroidal antiinflammatory drugs☆
Section snippets
Case 1
A 6-year-old girl had a 1-year history of intermittent abdominal pain. Computed tomography (CT) scan showed a large pelvic mass suggestive of a sarcoma. The mass measured 3 × 6 × 8 cm, with ipsilateral hydroureter and hydronephrosis (Fig 1A and B).The patient
Discussion
IPT is characterized by the benign proliferation of myofibroblasts and inflammatory infiltrate with a resultant mass.4, 5, 6 It often is difficult to differentiate IPT from a true malignancy because of the symptomatology, physical examination, and imaging findings.7 Clinically, patients with IPT can present with fever, leukocytosis, anemia, abdominal mass, and pain.1, 2, 4, 5, 6, 7 The radiolographic and operative findings of IPT resemble a true malignancy, because often it shows adherence to
References (8)
- et al.
Inflammatory pseudotumor of the diaphragm
Pediatr Surg Int
(1999) - et al.
Inflammatory pseudotumor causing intestinal obstruction: Diagnostic and therapeutic aspects
J Pediatr Surg
(1998) - et al.
Improvement of inflammatory pseudotumor of the liver after nonsteroidal anti-inflammatory agent therapy
Am J Gastroenterol
(1993) - et al.
Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor)
Am J Surg Pathol
(1995)
Cited by (74)
Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges
2021, Current Problems in CancerCitation Excerpt :The first report of an adult patient with IMT of liver responding to NASID treatment was published in 1993.51 Subsequently, tumor response to NSAIDs has been reported in children with abdominal and pancreatic IMT.49,52 In contrast, other reports demonstrate no response with NSAIDs and glucocorticoids.48
Inflammatory myofibroblastic tumors of the duodenum
2016, Asian Journal of SurgeryBenign Lung Tumors
2015, Murray and Nadel's Textbook of Respiratory Medicine: Volume 1,2, Sixth EditionTargeting Oncogenic Pathways in Dermatofibrosarcoma Protuberans and Inflammatory Myofibroblastic Tumor
2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease MechanismsTargeted Therapies in Rare Sarcomas. IMT, ASPS, SFT, PEComa, and CCS
2013, Hematology/Oncology Clinics of North AmericaInfantile inflammatory myofibroblastic tumour of the sigmoid colon: A diagnostic dilemma
2023, BMJ Case Reports
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Address reprint requests to Harry Applebaum, MD, Department of Surgery, Kaiser Permanente Medical Center, 4747 Sunset Blvd, Los Angeles, CA 90029.