Anästhesiol Intensivmed Notfallmed Schmerzther 2020; 55(10): 635-642
DOI: 10.1055/a-1011-2078
Leitlinien in der Praxis

Leitlinien in der Praxis: der herzchirurgische Patient in der intensivmedizinischen Versorgung

S3-Guideline Intensive Care Therapy of Cardiac Surgery Patients – a Practical Approach
David Sander
,
Fabian Dusse

Zusammenfassung

Die S3-Leitlinie zur intensivmedizinischen Versorgung herzchirurgischer Patienten – Hämodynamisches Monitoring und Herz-Kreislauf [1] vereint aktuelles Wissen zu Empfehlungen für das hämodynamische Monitoring und die differenzierte Kreislauftherapie bei herzchirurgischen Intensivpatienten. Zudem werden anzustrebende Zielparameter der Kreislauftherapie, Behandlungsstrategien bei Links- und Rechtsherzinsuffizienz sowie klare Handlungsempfehlungen nach diversen Eingriffen in diesem Patientenkollektiv aufgezeigt.

Abstract

The current S3-Guideline for intensive care therapy in patients after cardiac surgery provides a wealth of information and recommendations ranging from monitoring to treatment options for various perioperative clinical situations. This article focuses on the most relevant information applicable to every-day critical care practice, covering important aspects of general and advanced monitoring, goal directed hemodynamic therapy and treatment principles for perioperative left and right heart failure.

Kernaussagen
  • Gemischt-venöse und/oder zentralvenöse Sättigung in Zusammenschau mit Laktatwert bewerten.

  • Ein erweitertes Monitoring sollte mit einer zielorientierten Therapie verbunden sein.

  • Künstliche Kolloide und Albumin spielen eine wichtige Rolle in der Volumenersatztherapie.

  • Levosimendan kann eine schwere Hypotonie bedingen.

  • Die Therapie der Rechtsherzinsuffizienz stützt sich auf adäquaten Perfusionsdruck, Kontraktilitätsverbesserung und Senkung eines erhöhten pulmonalvaskulären Widerstandes (PVR).



Publication History

Article published online:
14 October 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • Literatur

  • 1 Habicher M, Zajonz T, Bauer A. et al. S3-Leitlinie zur intensivmedizinischen Versorgung herzchirurgischer Patienten – Hämodynamisches Monitoring und Herz-Kreislauf. AWMF Register Nr. 001/016. Im Internet (Stand: 07.09.2020): https://www.awmf.org/leitlinien/detail/ll/001-016.html
  • 2 Funcke S, Sander M, Goepfert MS. et al. Practice of hemodynamic monitoring and management in German, Austrian, and Swiss intensive care units: the multicenter cross-sectional ICU-CardioMan Study. Ann Intensive Care 2016; 6: 49
  • 3 Kastrup M, Carl M, Spies C. et al. Clinical impact of the publication of S3 guidelines for intensive care in cardiac surgery patients in Germany: results from a postal survey. Acta Anaesthesiol Scand 2013; 57: 206-213
  • 4 London MJ, Hollenberg M, Wong MG. et al. Intraoperative myocardial ischemia: localization by continuous 12-lead electrocardiography. Anesthesiology 1988; 69: 232-241
  • 5 Bur A, Hirschl MM, Herkner H. et al. Accuracy of oscillometric blood pressure measurement according to the relation between cuff size and upper-arm circumference in critically ill patients. Crit Care Med 2000; 28: 371-376
  • 6 Hollenberg SM, Ahrens TS, Annane D. et al. Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med 2004; 32: 1928-1948
  • 7 Hu BY, Laine GA, Wang S. et al. Combined central venous oxygen saturation and lactate as markers of occult hypoperfusion and outcome following cardiac surgery. J Cardiothorac Vasc Anesth 2012; 26: 52-57
  • 8 Williams JB, Peterson ED, Wojdyla D. et al. Central venous pressure after coronary artery bypass surgery: does it predict postoperative mortality or renal failure?. J Crit Care 2014; 29: 1006-1010
  • 9 Aya HD, Cecconi M, Hamilton M. et al. Goal-directed therapy in cardiac surgery: a systematic review and meta-analysis. Br J Anaesth 2013; 110: 510-517
  • 10 Hainer C, Bernhard M, Scheuren K. et al. [Echocardiography during acute hemodynamic instability]. Anaesthesist 2006; 55: 1117-1131
  • 11 Treskatsch S, Habicher M, Sander M. Echokardiografie als Monitoring auf der Intensivstation?. Anaesthesiol Intensivmed Notfallmed Schmerzther 2014; 49: 708-717
  • 12 Trottier SJ, Taylor RW. Physiciansʼ attitudes toward and knowledge of the pulmonary artery catheter: Society of Critical Care Medicine membership survey. New Horiz 1997; 5: 201-206
  • 13 Gurgel ST, do Nascimento P. Maintaining tissue perfusion in high-risk surgical patients: a systematic review of randomized clinical trials. Anesth Analg 2011; 112: 1384-1391
  • 14 Hamilton MA, Cecconi M, Rhodes A. A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 2011; 112: 1392-1402
  • 15 Gödje O, Höke K, Goetz AE. et al. Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability. Crit Care Med 2002; 30: 52-58
  • 16 Zöllner C, Haller M, Weis M. et al. Beat-to-beat measurement of cardiac output by intravascular pulse contour analysis: a prospective criterion standard study in patients after cardiac surgery. J Cardiothorac Vasc Anesth 2000; 14: 125-129
  • 17 Laine GA, Hu BY, Wang S. et al. Isolated high lactate or low central venous oxygen saturation after cardiac surgery and association with outcome. J Cardiothorac Vasc Anesth 2013; 27: 1271-1276
  • 18 Annane D, Siami S, Jaber S. et al. Effects of fluid resuscitation with colloids vs. crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomized trial. JAMA 2013; 310: 1809-1817
  • 19 Gillies MA, Habicher M, Jhanji S. et al. Incidence of postoperative death and acute kidney injury associated with i.v. 6 % hydroxyethyl starch use: systematic review and meta-analysis. Br J Anaesth 2014; 112: 25-34
  • 20 Kim J-Y, Joung K-W, Kim K-M. et al. Relationship between a perioperative intravenous fluid administration strategy and acute kidney injury following off-pump coronary artery bypass surgery: an observational study. Crit Care 2015; 19: 350
  • 21 Saw MM, Chandler B, Ho KM. Benefits and risks of using gelatin solution as a plasma expander for perioperative and critically ill patients: a meta-analysis. Anaesth Intensive Care 2012; 40: 17-32
  • 22 Karas PL, Goh SL, Dhital K. Is low serum albumin associated with postoperative complications in patients undergoing cardiac surgery?. Interact Cardiovasc Thorac Surg 2015; 21: 777-786
  • 23 Chen Q-H, Zheng R-Q, Lin H. et al. Effect of levosimendan on prognosis in adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials. Crit Care 2017; 21: 253
  • 24 Sanfilippo F, Knight JB, Scolletta S. et al. Levosimendan for patients with severely reduced left ventricular systolic function and/or low cardiac output syndrome undergoing cardiac surgery: a systematic review and meta-analysis. Crit Care 2017; 21: 252
  • 25 Packer M, Colucci W, Fisher L. et al. Effect of levosimendan on the short-term clinical course of patients with acutely decompensated heart failure. JACC Heart Fail 2013; 1: 103-111
  • 26 Maharaj R, Metaxa V. Levosimendan and mortality after coronary revascularisation: a meta-analysis of randomised controlled trials. Crit Care 2011; 15: R140
  • 27 Harrison RW, Hasselblad V, Mehta RH. et al. Effect of levosimendan on survival and adverse events after cardiac surgery: a meta-analysis. J Cardiothorac Vasc Anesth 2013; 27: 1224-1232
  • 28 Belletti A, Castro ML, Silvetti S. et al. The Effect of inotropes and vasopressors on mortality: a meta-analysis of randomized clinical trials. Br J Anaesth 2015; 115: 656-675
  • 29 Landoni G, Lomivorotov VV, Alvaro G. et al. Levosimendan for Hemodynamic Support after Cardiac Surgery. N Engl J Med 2017; 376: 2021-2031
  • 30 Winterhalter M, Antoniou T, Loukanov T. Management of adult patients with perioperative pulmonary hypertension: technical aspects and therapeutic options. Cardiology 2010; 116: 3-9
  • 31 Ponikowski P, Voors AA, Anker SD. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2016; 37: 2129-2200