Semin Respir Crit Care Med 2012; 33(03): 213-219
DOI: 10.1055/s-0032-1315633
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Global Changes in the Epidemiology of Community-Acquired Pneumonia

Timothy L. Wiemken
1   Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky.
,
Paula Peyrani
1   Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky.
,
Julio A. Ramirez
1   Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, Kentucky.
› Author Affiliations
Further Information

Publication History

Publication Date:
20 June 2012 (online)

Abstract

Lower respiratory tract infections are the most common infectious cause of death in the world and the third most common cause of death globally (all causes). This article reviews the epidemiology of community-acquired pneumonia from a global perspective. Major areas of epidemiological work include (1) disease surveillance to define the burden of disease and to document outbreaks, (2) identification of risk factors for a disease to optimize prevention strategies, and (3) comparisons of treatment effects to improve clinical outcomes for patients with the disease.

 
  • References

  • 1 Top 10 causes of death. 2008. http://www.who.int/mediacentre/factsheets/fs310/en/ . Accessed November 22, 2011
  • 2 Centers for Disease Control and Prevention (CDC). Leading Causes of Death Reports. 2007. http://webappa.cdc.gov/sasweb/ncipc/leadcaus10.html . Accessed August 26, 2011
  • 3 Wiemken T, Peyrani P, Arnold FW, Ramirez J. The use of large databases to study pneumonia: what is their value?. Clin Chest Med 2011; 32 (3) 481-489
  • 4 Welte T, Köhnlein T. Global and local epidemiology of community-acquired pneumonia: the experience of the CAPNETZ Network. Semin Respir Crit Care Med 2009; 30 (2) 127-135
  • 5 Ramirez JA. Fostering international multicenter collaborative research: the CAPO Project. Int J Tuberc Lung Dis 2007; 11 (10) 1062-1065
  • 6 Foy HM, Kenny GE, Cooney MK, Allan ID. Long-term epidemiology of infections with Mycoplasma pneumoniae. J Infect Dis 1979; 139 (6) 681-687
  • 7 Jokinen C, Heiskanen L, Juvonen H , et al. Incidence of community-acquired pneumonia in the population of four municipalities in eastern Finland. Am J Epidemiol 1993; 137 (9) 977-988
  • 8 Almirall J, Bolíbar I, Vidal J , et al. Epidemiology of community-acquired pneumonia in adults: a population-based study. Eur Respir J 2000; 15 (4) 757-763
  • 9 Marston BJ, Plouffe JF, File Jr TM , et al; The Community-Based Pneumonia Incidence Study Group. Incidence of community-acquired pneumonia requiring hospitalization: results of a population-based active surveillance Study in Ohio. Arch Intern Med 1997; 157 (15) 1709-1718
  • 10 Niederman MS, Mandell LA, Anzueto A , et al; American Thoracic Society. Guidelines for the management of adults with community-acquired pneumonia: diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am J Respir Crit Care Med 2001; 163 (7) 1730-1754
  • 11 File TM. Community-acquired pneumonia. Lancet 2003; 362 (9400) 1991-2001
  • 12 Arnold FW, Summersgill JT, Lajoie AS , et al; Community-Acquired Pneumonia Organization (CAPO) Investigators. A worldwide perspective of atypical pathogens in community-acquired pneumonia. Am J Respir Crit Care Med 2007; 175 (10) 1086-1093
  • 13 Johnstone J, Majumdar SR, Fox JD, Marrie TJ. Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest 2008; 134 (6) 1141-1148
  • 14 Wiemken T, Cabral P, Peyrani P , et al. Severe Influenza Pneumonia Surveillance (SIPS) Project: a tool for the detection of human and non-human strains of influenza A in Kentucky. Paper presented at: 47th International Meeting of the Infectious Diseases Society of America; Oct 29–Nov 1 2009; Philadelphia, PA, Abstract 522
  • 15 American Thoracic Society; Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171 (4) 388-416
  • 16 Ewig S, Welte T, Chastre J, Torres A. Rethinking the concepts of community-acquired and health-care-associated pneumonia. Lancet Infect Dis 2010; 10 (4) 279-287
  • 17 Drosten C, Günther S, Preiser W , et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003; 348 (20) 1967-1976
  • 18 Riley TV, Rouse IL. Methicillin-resistant Staphylococcus aureus in Western Australia, 1983-1992. J Hosp Infect 1995; 29 (3) 177-188
  • 19 Centers for Disease Control and Prevention (CDC). Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus — Minnesota and North Dakota, 1997-1999. MMWR Morb Mortal Wkly Rep 1999; 48 (32) 707-710
  • 20 Perez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S , et al; INER Working Group on Influenza. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med 2009; 361 (7) 680-689
  • 21 Riquelme R, Riquelme M, Rioseco ML , et al. Characteristics of hospitalised patients with 2009 H1N1 influenza in Chile. Eur Respir J 2010; 36 (4) 864-869
  • 22 Centers for Disease Control and Prevention (CDC). Intensive-care patients with severe novel influenza A (H1N1) virus infection - Michigan, June 2009. MMWR Morb Mortal Wkly Rep 2009; 58 (27) 749-752
  • 23 Centers for Disease Control and Prevention (CDC). Emergency preparedness and response: bioterrorism agents/diseases. http://www.bt.cdc.gov/agent/agentlist-category.asp . Accessed November 27, 2011
  • 24 Mandell LA, Wunderink RG, Anzueto A , et al; Infectious Diseases Society of America; American Thoracic Society. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007; 44 (Suppl. 02) S27-S72
  • 25 Pitsiou GG, Kioumis IP. Pneumococcal vaccination in adults: does it really work?. Respir Med 2011; 105 (12) 1776-1783
  • 26 Caplan A. Time to mandate influenza vaccination in health-care workers. Lancet 2011; 378 (9788) 310-311
  • 27 Kidd F, Wones R, Momper A, Bechtle M, Lewis M. From 51% to 100%: mandatory seasonal influenza vaccination. Am J Infect Control 2012; 40 (2) 188-190
  • 28 Ramirez JA, Srinath L, Ahkee S, Huang A, Raff MJ. Early switch from intravenous to oral cephalosporins in the treatment of hospitalized patients with community-acquired pneumonia. Arch Intern Med 1995; 155 (12) 1273-1276
  • 29 Labandeira-Rey M, Couzon F, Boisset S , et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 2007; 315 (5815) 1130-1133
  • 30 Micek ST, Dunne M, Kollef MH. Pleuropulmonary complications of Panton-Valentine leukocidin-positive community-acquired methicillin-resistant Staphylococcus aureus: importance of treatment with antimicrobials inhibiting exotoxin production. Chest 2005; 128 (4) 2732-2738
  • 31 Snijders D, Daniels JM, de Graaff CS, van der Werf TS, Boersma WG. Efficacy of corticosteroids in community-acquired pneumonia: a randomized double-blinded clinical trial. Am J Respir Crit Care Med 2010; 181 (9) 975-982
  • 32 Fernández-Serrano S, Dorca J, Garcia-Vidal C , et al. Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial. Crit Care 2011; 15 (2) R96
  • 33 Caballero J, Rello J. Combination antibiotic therapy for community-acquired pneumonia. Ann Intensive Care 2011; 1: 48
  • 34 Martin-Loeches I, Lisboa T, Rodriguez A , et al. Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia. Intensive Care Med 2010; 36 (4) 612-620
  • 35 Restrepo MI, Mortensen EM, Waterer GW, Wunderink RG, Coalson JJ, Anzueto A. Impact of macrolide therapy on mortality for patients with severe sepsis due to pneumonia. Eur Respir J 2009; 33 (1) 153-159
  • 36 Frei CR, Attridge RT, Mortensen EM , et al. Guideline-concordant antibiotic use and survival among patients with community-acquired pneumonia admitted to the intensive care unit. Clin Ther 2010; 32 (2) 293-299
  • 37 Frei CR, Restrepo MI, Mortensen EM, Burgess DS. Impact of guideline-concordant empiric antibiotic therapy in community-acquired pneumonia. Am J Med 2006; 119 (10) 865-871
  • 38 Restrepo MI, Mortensen EM, Rello J, Brody J, Anzueto A. Late admission to the ICU in patients with community-acquired pneumonia is associated with higher mortality. Chest 2010; 137 (3) 552-557
  • 39 Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med 2009; 360 (14) 1418-1428
  • 40 Bordon J, Wiemken T, Peyrani P , et al; CAPO Study Group. Decrease in long-term survival for hospitalized patients with community-acquired pneumonia. Chest 2010; 138 (2) 279-283
  • 41 Aliberti S, Amir A, Peyrani P , et al. Incidence, etiology, timing, and risk factors for clinical failure in hospitalized patients with community-acquired pneumonia. Chest 2008; 134 (5) 955-962
  • 42 Ramirez J, Aliberti S, Mirsaeidi M , et al. Acute myocardial infarction in hospitalized patients with community-acquired pneumonia. Clin Infect Dis 2008; 47 (2) 182-187
  • 43 Yende S, D'Angelo G, Kellum JA , et al; GenIMS Investigators. Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis. Am J Respir Crit Care Med 2008; 177 (11) 1242-1247