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Semin intervent Radiol 2013; 30(02): 157-168
DOI: 10.1055/s-0033-1342957
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Imaging Features following Thermal Ablation of Lung Malignancies

Sophie Chheang
1   Division of Interventional Radiology, Department of Radiology, Weill Cornell Medical College, New York-Presbyterian Hospital, New York, New York
,
Feredoin Abtin
2   Thoracic Imaging Section, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California
,
Antonio Guteirrez
2   Thoracic Imaging Section, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California
,
Scott Genshaft
2   Thoracic Imaging Section, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California
,
Robert Suh
2   Thoracic Imaging Section, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California
› Author Affiliations
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Publication History

Publication Date:
28 May 2013 (online)

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Abstract

Percutaneous image-guided thermal ablation is gaining attraction as an effective alternative to surgical resection for patients with primary and secondary malignancies of the lung. Currently, no standard follow-up imaging protocol has been established or uniformly accepted. The early identification of residual or recurrent tumor would in theory enable the practitioner to offer expeditious retreatment or alternative treatment. This review elaborates on the imaging findings following thermal ablation, both heat- and cold-based, of nonresectable pulmonary malignancies.

Keywords

lung cancer - thermal ablation - imaging findings - positron emission tomography - computed tomography - radiofrequency - microwave - cryotherapy
 

  • References

  • 1 Surveillance Epidemiology and End Results (SEER). Available at : http://seer.cancer.gov/csr/1975_2009_pops09/
    PubMedGoogle Scholar
  • 2 Dupuy DE, Zagoria RJ, Akerley W, Mayo-Smith WW, Kavanagh PV, Safran H. Percutaneous radiofrequency ablation of malignancies in the lung. AJR Am J Roentgenol 2000; 174 (1) 57-59
    CrossrefPubMedGoogle Scholar
  • 3 Giraud P, Antoine M, Larrouy A , et al. Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning. Int J Radiat Oncol Biol Phys 2000; 48 (4) 1015-1024
    CrossrefPubMedGoogle Scholar
  • 4 Abtin FG, Eradat J, Gutierrez AJ, Lee C, Fishbein MC, Suh RD. Radiofrequency ablation of lung tumors: imaging features of the postablation zone. Radiographics 2012; 32 (4) 947-969
    CrossrefPubMedGoogle Scholar
  • 5 Beland MD, Wasser EJ, Mayo-Smith WW, Dupuy DE. Primary non-small cell lung cancer: review of frequency, location, and time of recurrence after radiofrequency ablation. Radiology 2010; 254 (1) 301-307
    PubMedGoogle Scholar
  • 6 Hiraki T, Tajiri N, Mimura H , et al. Pneumothorax, pleural effusion, and chest tube placement after radiofrequency ablation of lung tumors: incidence and risk factors. Radiology 2006; 241 (1) 275-283
    CrossrefPubMedGoogle Scholar
  • 7 Gazelle GS, Goldberg SN, Solbiati L, Livraghi T. Tumor ablation with radio-frequency energy. Radiology 2000; 217 (3) 633-646
    CrossrefPubMedGoogle Scholar
  • 8 Anderson EM, Lees WR, Gillams AR. Early indicators of treatment success after percutaneous radiofrequency of pulmonary tumors. Cardiovasc Intervent Radiol 2009; 32 (3) 478-483
    CrossrefPubMedGoogle Scholar
  • 9 Wolf FJ, Grand DJ, Machan JT, Dipetrillo TA, Mayo-Smith WW, Dupuy DE. Microwave ablation of lung malignancies: effectiveness, CT findings, and safety in 50 patients. Radiology 2008; 247 (3) 871-879
    CrossrefPubMedGoogle Scholar
  • 10 Lee JM, Jin GY, Goldberg SN , et al. Percutaneous radiofrequency ablation for inoperable non-small cell lung cancer and metastases: preliminary report. Radiology 2004; 230 (1) 125-134
    CrossrefPubMedGoogle Scholar
  • 11 Yamamoto A, Nakamura K, Matsuoka T , et al. Radiofrequency ablation in a porcine lung model: correlation between CT and histopathologic findings. AJR Am J Roentgenol 2005; 185 (5) 1299-1306
    CrossrefPubMedGoogle Scholar
  • 12 de Baère T, Palussière J, Aupérin A , et al. Midterm local efficacy and survival after radiofrequency ablation of lung tumors with minimum follow-up of 1 year: prospective evaluation. Radiology 2006; 240 (2) 587-596
    CrossrefPubMedGoogle Scholar
  • 13 Vogl TJ, Naguib NN, Gruber-Rouh T, Koitka K, Lehnert T, Nour-Eldin NE. Microwave ablation therapy: clinical utility in treatment of pulmonary metastases. Radiology 2011; 261 (2) 643-651
    CrossrefPubMedGoogle Scholar
  • 14 Ito N, Nakatsuka S, Inoue M , et al. Computed tomographic appearance of lung tumors treated with percutaneous cryoablation. J Vasc Interv Radiol 2012; 23 (8) 1043-1052
    CrossrefPubMedGoogle Scholar
  • 15 Therasse P, Arbuck SG, Eisenhauer EA , et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92 (3) 205-216
    CrossrefPubMedGoogle Scholar
  • 16 Goldberg SN, Grassi CJ, Cardella JF , et al; Society of Interventional Radiology Technology Assessment Committee ; International Working Group on Image-Guided Tumor Ablation. Image-guided tumor ablation: standardization of terminology and reporting criteria. Radiology 2005; 235 (3) 728-739
    CrossrefPubMedGoogle Scholar
  • 17 Hinshaw JL, Lee Jr FT. Cryoablation for liver cancer. Tech Vasc Interv Radiol 2007; 10 (1) 47-57
    CrossrefPubMedGoogle Scholar
  • 18 Simon CJ, Dupuy DE, Mayo-Smith WW. Microwave ablation: principles and applications. Radiographics 2005; 25 (Suppl. 01) S69-S83
    CrossrefPubMedGoogle Scholar
  • 19 Wright AS, Sampson LA, Warner TF, Mahvi DM, Lee Jr FT. Radiofrequency versus microwave ablation in a hepatic porcine model. Radiology 2005; 236 (1) 132-139
    Google Scholar
  • 20 Suh RD, Wallace AB, Sheehan RE, Heinze SB, Goldin JG. Unresectable pulmonary malignancies: CT-guided percutaneous radiofrequency ablation—preliminary results. Radiology 2003; 229 (3) 821-829
    CrossrefPubMedGoogle Scholar
  • 21 Steinke K, King J, Glenn D, Morris DL. Radiologic appearance and complications of percutaneous computed tomography-guided radiofrequency-ablated pulmonary metastases from colorectal carcinoma. J Comput Assist Tomogr 2003; 27 (5) 750-757
    CrossrefPubMedGoogle Scholar
  • 22 Sharma A, Digumarthy SR, Kalra MK, Lanuti M, Shepard JA. Reversible locoregional lymph node enlargement after radiofrequency ablation of lung tumors. AJR Am J Roentgenol 2010; 194 (5) 1250-1256
    CrossrefPubMedGoogle Scholar
  • 23 Okuma T, Okamura T, Matsuoka T , et al. Fluorine-18-fluorodeoxyglucose positron emission tomography for assessment of patients with unresectable recurrent or metastatic lung cancers after CT-guided radiofrequency ablation: preliminary results. Ann Nucl Med 2006; 20 (2) 115-121
    CrossrefPubMedGoogle Scholar
  • 24 Yoo DC, Dupuy DE, Hillman SL , et al. Radiofrequency ablation of medically inoperable stage IA non-small cell lung cancer: are early posttreatment PET findings predictive of treatment outcome?. AJR Am J Roentgenol 2011; 197 (2) 334-340
    CrossrefPubMedGoogle Scholar
  • 25 Rose SC, Thistlethwaite PA, Sewell PE, Vance RB. Lung cancer and radiofrequency ablation. J Vasc Interv Radiol 2006; 17 (6) 927-951 ; quiz 951
    CrossrefPubMedGoogle Scholar
  • 26 Chan VO, McDermott S, Malone DE, Dodd JD. Percutaneous radiofrequency ablation of lung tumors: evaluation of the literature using evidence-based techniques. J Thorac Imaging 2011; 26 (1) 18-26
    CrossrefPubMedGoogle Scholar
  • 27 Kawamura M, Izumi Y, Tsukada N , et al. Percutaneous cryoablation of small pulmonary malignant tumors under computed tomographic guidance with local anesthesia for nonsurgical candidates. J Thorac Cardiovasc Surg 2006; 131 (5) 1007-1013
    CrossrefPubMedGoogle Scholar
  • 28 Gillams A. Tumour ablation: current role in the kidney, lung and bone. Cancer Imaging 2009; (9 Spec No A) S68-S70
    PubMedGoogle Scholar
  • 29 Yamakado K, Hase S, Matsuoka T , et al. Radiofrequency ablation for the treatment of unresectable lung metastases in patients with colorectal cancer: a multicenter study in Japan. J Vasc Interv Radiol 2007; 18 (3) 393-398
    CrossrefPubMedGoogle Scholar
  • 30 Cannella M, Cornelis F, Descat E , et al. Bronchopleural fistula after radiofrequency ablation of lung tumours. Cardiovasc Intervent Radiol 2011; 34 (Suppl. 02) S171-S174
    CrossrefPubMedGoogle Scholar
  • 31 Bui JT, Gaba RC, Knuttinen MG , et al. Microwave lung ablation complicated by bronchocutaneous fistula: case report and literature review. Semin Intervent Radiol 2011; 28 (2) 152-155
    Article in Thieme ConnectPubMedGoogle Scholar
  • 32 Bojarski JD, Dupuy DE, Mayo-Smith WW. CT imaging findings of pulmonary neoplasms after treatment with radiofrequency ablation: results in 32 tumors. AJR Am J Roentgenol 2005; 185 (2) 466-471
    CrossrefPubMedGoogle Scholar
  • 33 Singnurkar A, Solomon SB, Gönen M, Larson SM, Schöder H. 18F-FDG PET/CT for the prediction and detection of local recurrence after radiofrequency ablation of malignant lung lesions. J Nucl Med 2010; 51 (12) 1833-1840
    CrossrefPubMedGoogle Scholar
  • 34 Sakurai J, Hiraki T, Mukai T , et al. Intractable pneumothorax due to bronchopleural fistula after radiofrequency ablation of lung tumors. J Vasc Interv Radiol 2007; 18 (1 Pt 1) 141-145
    CrossrefPubMedGoogle Scholar
  • 35 Wang H, Littrup PJ, Duan Y, Zhang Y, Feng H, Nie Z. Thoracic masses treated with percutaneous cryotherapy: initial experience with more than 200 procedures. Radiology 2005; 235 (1) 289-298
    CrossrefPubMedGoogle Scholar
  • 36 Saliken JC, McKinnon JG, Gray R. CT for monitoring cryotherapy. AJR Am J Roentgenol 1996; 166 (4) 853-855
    CrossrefPubMedGoogle Scholar
  • 37 Izumi Y, Oyama T, Ikeda E, Kawamura M, Kobayashi K. The acute effects of transthoracic cryoablation on normal lung evaluated in a porcine model. Ann Thorac Surg 2005; 79 (1) 318-322 ; discussion 322
    CrossrefPubMedGoogle Scholar
  • 38 Hinshaw JL, Littrup PJ, Durick N , et al. Optimizing the protocol for pulmonary cryoablation: a comparison of a dual- and triple-freeze protocol. Cardiovasc Intervent Radiol 2010; 33 (6) 1180-1185
    CrossrefPubMedGoogle Scholar
  • 39 Permpongkosol S, Nicol TL, Link RE , et al. Differences in ablation size in porcine kidney, liver, and lung after cryoablation using the same ablation protocol. AJR Am J Roentgenol 2007; 188 (4) 1028-1032
    CrossrefPubMedGoogle Scholar
  • 40 Niu L, Li J, Chen J , et al. Comparison of dual- and triple-freeze protocols for pulmonary cryoablation in a Tibet pig model. Cryobiology 2012; 64 (3) 245-249
    CrossrefPubMedGoogle Scholar