Laryngorhinootologie 2015; 94(04): 250-269
DOI: 10.1055/s-0035-1547290
Facharztwissen HNO
© Georg Thieme Verlag KG Stuttgart · New York

Allergische Rhinitis im Kontext der chronischen Rhinosinusitis

K. Geißler
,
O. Guntinas-Lichius
Further Information

Publication History

Publication Date:
02 April 2015 (online)

Zusammenfassung

Die chronische Rhinosinusitis gehört zu den häufigsten chronischen Erkrankungen. Eine wichtige Ursache ist die allergische Rhinitis. Beide Erkrankungen und die Kombination von beiden, die im Mittelpunkt dieses Weiterbildungsbeitrags stehen, als auch die Abklärung und Behandlung der Differenzialdiagnosen gehören in die Hände des HNO-Arztes. Letztendlich ist nicht geklärt, warum eine allergische Rhinitis zu einer chronischen Rhinosinusitis führt. Zur Diagnostik und Therapie der allergischen Rhinosinusitis steht als Behandlungsrichtlinie eine Reihe von gut ausgearbeiteten nationalen und internationalen Leitlinien zur Verfügung. Dieser Beitrag stellt die wichtigsten aktuellen diagnostischen und therapeutischen Verfahren zur Behandlung derallergischen Rhinitis im Kindesalter und im Erwachsenenalter vor.

Abstract

Chronic Rhinosinusitis is one of the most frequent chronic diseases. A major cause is allergic rhinitis. Both illnesses and the combination of both, which is the topic of this educational article, as well as the clarification and therapy of differential diagnoses are belonging in the hands of the otorhinolaryngologist. Finally, it is not completely understood which mechanisms of the allergic inflammation in the nose lead or predispose in the individual patient to the development of a chronic sinus disease. A series of excellent national and international guidelines have been published supporting the otorhinolaryngologist in diagnostics and treatment of patients with allergic rhinosinusitis. This article presents the most important and actual diagnostic and therapeutic procedures for the treatment of this important chronic disease in children and adults.

 
  • Literatur

  • 1 Bousquet J, Khaltaev N, Cruz AA et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008; 63: 8-160
  • 2 Brozek JL, Bousquet J, Baena-Cagnani CE et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol 2010; 126: 466-476
  • 3 Stuck BA, Bachert C, Federspil P et al. Rhinosinusitis guidelines – unabridged version: S2 guidelines from the German Society of Otorhinolaryngology, Head and Neck Surgery. HNO 2012; 60: 141-162
  • 4 Riechelmann H. Europäische Akademie fur Allergie und Klinische Immunologie und der European Rhinologic Society. Chronic Rhinosinusitis – EPOS 2012 Part I. Laryngorhinootologie 2013; 92: 193-201 quiz 202–203
  • 5 Riechelmann H, Giotakis A, Kral F. Acute rhinosinusitis in adults – EPOS 2012 Part II. Laryngorhinootologie 2013; 92: 763-776
  • 6 Fokkens WJ, Lund VJ, Mullol J et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012; 50: 1-12
  • 7 DeYoung K, Wentzel JL, Schlosser RJ et al. Systematic review of immunotherapy for chronic rhinosinusitis. Am J Rhinol Allergy 2014; 28: 145-150
  • 8 Kim YH, Jang TY. Usefulness of the subjective cold hyperresponsiveness scale as evaluated by cold dry air provocation. Am J Rhinol Allergy 2012; 26: 45-48
  • 9 Bousquet J, Heinzerling L, Bachert C et al. Practical guide to skin prick tests in allergy to aeroallergens. Allergy 2012; 67: 18-24
  • 10 Stuck BA, Bachert C, Federspil P et al. Rhinosinusitis guidelines of the German Society for Otorhinolaryngology, Head and Neck Surgery. HNO 2007; 55: 758-760 762–764, 766–777
  • 11 Liu Q, Lu X, Bo M et al. The microbiology of chronic rhinosinusitis with and without nasal polyps. Acta Otolaryngol 2014; 134: 1251-1258
  • 12 Tan BK, Chandra RK, Pollak J et al. Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis. J Allergy Clin Immunol 2013; 131: 1350-1360
  • 13 Hur K, Liang J, Lin SY. The role of secondhand smoke in allergic rhinitis: a systematic review. Int Forum Allergy Rhinol 2014; 4: 110-116
  • 14 Hur K, Liang J, Lin SY. The role of secondhand smoke in sinusitis: a systematic review. Int Forum Allergy Rhinol 2014; 4: 22-28
  • 15 Sidell D, Shapiro NL, Bhattacharyya N. Obesity and the risk of chronic rhinosinusitis, allergic rhinitis, and acute otitis media in school-age children. Laryngoscope 2013; 123: 2360-2363
  • 16 Terreehorst I, Hak E, Oosting AJ et al. Evaluation of impermeable covers for bedding in patients with allergic rhinitis. New Engl J Med 2003; 349: 237-246
  • 17 Hermelingmeier KE, Weber RK, Hellmich M et al. Nasal irrigation as an adjunctive treatment in allergic rhinitis: a systematic review and meta-analysis. Am J Rhinol Allergy 2012; 26: e119-e125
  • 18 Schlenter WW, Blessing R, Heintz B. Conservative treatment of chronic sinusitis. Success of oral bacterial lysate therapy. Laryngorhinootologie 1989; 68: 671-674
  • 19 Kaplan A. Canadian guidelines for chronic rhinosinusitis: Clinical summary. Can Fam Physician 2013; 59: 1275-1281 e1528–e1234
  • 20 Meadows A, Kaambwa B, Novielli N et al. A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis. Health Technol Assess 2013; 17 vi, xi–xiv 1-322
  • 21 Erekosima N, Suarez-Cuervo C, Ramanathan M et al. Effectiveness of subcutaneous immunotherapy for allergic rhinoconjunctivitis and asthma: a systematic review. Laryngoscope 2014; 124: 616-627
  • 22 Grundmann SA, Mosters P, Brehler R. Specific immunotherapy. Hautarzt 2014; 65: 633-645 quiz 646–647
  • 23 Matricardi PM, Kuna P, Panetta V et al. Subcutaneous immunotherapy and pharmacotherapy in seasonal allergic rhinitis: a comparison based on meta-analyses. J Allergy Clin Immunol 2011; 128: 791-799 e796
  • 24 Radulovic S, Wilson D, Calderon M et al. Systematic reviews of sublingual immunotherapy (SLIT). Allergy 2011; 66: 740-752
  • 25 Horak F, Zieglmayer P, Zieglmayer R et al. Early onset of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamber. J Allergy Clin Immunol 2009; 124: 471-477 e471
  • 26 Feng S, Xu Y, Ma R et al. Cluster subcutaneous allergen specific immunotherapy for the treatment of allergic rhinitis: a systematic review and meta-analysis. PloS one 2014; 9: e86529
  • 27 Jose J, Coatesworth AP. Inferior turbinate surgery for nasal obstruction in allergic rhinitis after failed medical treatment. The Cochrane database of systematic reviews 2010;
  • 28 Rudmik L, Mace J, Soler ZM et al. Long-term utility outcomes in patients undergoing endoscopic sinus surgery. Laryngoscope 2014; 124: 19-23
  • 29 Rudmik L, Soler ZM, Mace JC et al. Economic evaluation of endoscopic sinus surgery versus continued medical therapy for refractory chronic rhinosinusitis. Laryngoscope 2015; 125: 25-32
  • 30 Georgalas C, Cornet M, Adriaensen G et al. Evidence-based surgery for chronic rhinosinusitis with and without nasal polyps. Curr Allergy Asthma Rep 2014; 14: 427
  • 31 Hellings PW, Fokkens WJ, Akdis C et al. Uncontrolled allergic rhinitis and chronic rhinosinusitis: where do we stand today?. Allergy 2013; 68: 1-7
  • 32 Veling MC. The role of allergy in pediatric rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 2013; 21: 271-276
  • 33 Stenner M, Rudack C. Diseases of the nose and paranasal sinuses in childhood. Laryngorhinootologie 2014; 93: 24-48
  • 34 Braido F, Sclifo F, Ferrando M et al. New therapies for allergic rhinitis. Curr Allergy Asthma Rep 2014; 14: 422
  • 35 Braido F, Arcadipane F, Marugo F et al. Allergic rhinitis: current options and future perspectives. Curr Opin Allergy Clin Immunol 2014; 14: 168-176
  • 36 Bonini M, Di Maria G, Paggiaro P et al. Potential benefit of omalizumab in respiratory diseases. Ann Allergy Asthma Immunol 2014; 113: 513-519
  • 37 Solelhac G, Charpin D. Management of allergic rhinitis. F1000Prime Rep 2014; 6: 94
  • 38 Bachert C, Van Bruaene N, Toskala E et al. Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis – a GALEN study. Allergy 2009; 64: 520-533
  • 39 Akdis CA, Bachert C, Cingi C et al. Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 2013; 131: 1479-1490
  • 40 Eitenmuller A, Piano L, Bohm M et al. Liposomal Nasal Spray versus Guideline-Recommended Steroid Nasal Spray in Patients with Chronic Rhinosinusitis: A Comparison of Tolerability and Quality of Life. J Allergy (Cairo) 2014; - 2014:146280. DOI: 10.1155/2014/146280. Epub 2014 May 22
  • 41 Moller W, Schuschnig U, Celik G et al. Topical drug delivery in chronic rhinosinusitis patients before and after sinus surgery using pulsating aerosols. PloS one 2013; 8: e74991
  • 42 Bousquet J, Reid J, van Weel C et al. Allergic rhinitis management pocket reference 2008. Allergy 2008; 63: 990-996
  • 43 Mafee MF, Valvassori GE, Becker M. Imaging of the Head and Neck. Stuttgart: Thieme; 2005