Endoscopy 2016; 48(05): 440-447
DOI: 10.1055/s-0042-101406
Original article
© Georg Thieme Verlag KG Stuttgart · New York

Long-term outcomes of covered self-expandable metal stents for treating benign biliary strictures

Jin-Seok Park
1   Digestive Disease Center, Department of Internal Medicine, Inha University School of Medicine, Incheon, Republic of Korea
,
Sang Soo Lee
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
,
Tae Jun Song
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
,
Do Hyun Park
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
,
Dong-Wan Seo
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
,
Sung Koo Lee
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
,
Seungbong Han
3   Department of Applied Statistics, Gachon University, Seongnam, Republic of Korea
,
Myung-Hwan Kim
2   Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea
› Author Affiliations
Further Information

Publication History

submitted 03 June 2015

accepted after revision 01 December 2015

Publication Date:
26 February 2016 (online)

Background and study aim: Fully covered, self-expandable metal stents (FCSEMSs) are acceptable tools for treating benign biliary stricture (BBS). However, little is known about the long-term outcomes of this technique. The aim of the present study was to evaluate the procedural and long-term outcomes of FCSEMSs for treating BBSs.

Patients and methods: A total of 134 consecutive patients (median age 56 years; range 21 – 83) with BBS were retrospectively reviewed. The main outcomes were technical and clinical success, stricture resolution, recurrence, and adverse events. Outcomes were analyzed by reviewing patient medical records.

Results: The success rates of FCSEMS placement and removal were 99.3 % and 98.2 %, respectively. Stricture resolution occurred in 103/132 (78.0 %) of the patients (median stent duration, 93 days; range 1 – 489). The associated factors for stricture resolution were longer stent indwelling period (≥ 120 days) and absence of stent migration. Stricture recurrence was seen in 26/103 patients (25.2 %; 95 % confidence interval [CI] 0.17 – 0.34) within a median of 390 days (range 4 – 903 days). Chronic pancreatitis was associated with stricture recurrence (hazard ratio [HR] 2.59, 95 %CI 1.20 – 5.61; P = 0.02). Stent migration occurred in 41/132 patients (31.1 %; 95 %CI 0.23 – 0.39). The FCSEMS with anchoring flaps appeared to protect against stent migration (HR 0.22, 95 %CI 0.08 – 0.63; P < 0.01).

Conclusion: FCSEMSs had a high success rate for BBS resolution. Longer indwelling periods and the absence of stent migration might be important factors for stricture resolution.

 
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