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Semin Musculoskelet Radiol 2001; 05(2): 167-170
DOI: 10.1055/s-2001-15675
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Muscular Sarcoidosis

Shoichiro Otake1 , Takeo Ishigaki2
  • 1Department of Radiology, Toki Municipal General Hospital, Toki
  • 2Department of Radiology, Nagoya University School of Medicine, Nagoya, Japan
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Publication History

Publication Date:
31 December 2001 (online)

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ABSTRACT

There are four types of muscular sarcoidosis: nodular, chronic myopathy, acute myositis, and asymptomatic. The nodular type is important because it may be confused with a soft tissue tumor. Magnetic resonance (MR) imaging provides specific findings. A star-shaped central structure of decreased signal intensity, a ``dark star'' sign, is seen on the axial images. A long nodule with an inner stripe of decreased signal intensity and outer stripes of increased signal intensity, a ``three stripes'' sign, is seen on the coronal and sagittal images. In the chronic myopathy type, the role of MR imaging is limited. Gallium scintigraphy, which reflects activity of inflammation, may show increased uptake. In the acute myositis type, MR imaging shows increased signal intensity, and gallium scintigraphy shows increased uptake; however, these findings are nonspecific.

KEYWORD

Muscular sarcoidosis - magnetic resonance imaging - gallium scintigraphy

REFERENCES

  • 1 Zisman D A, Biermann J S, Martinez F J, Devaney K O, Lynch III P J. Sarcoidosis presenting as a tumorlike muscular lesion. Case report and review of the literature.  Medicine . 1999;  78 112-122
    CrossrefPubMedGoogle Scholar
  • 2 Silverstein A, Siltzbach L E. Muscle involvement in sarcoidosis. Asymptomatic, myositis, and myopathy.  Arch Neurol . 1969;  21 235-241
    PubMedGoogle Scholar
  • 3 Otake S. Sarcoidosis involving skeletal muscle: imaging findings and relative value of imaging procedures.  Am J Roentgenol . 1994;  162 369-375
    PubMedGoogle Scholar
  • 4 Otake S, Banno T, Ohba S, Noda M, Yamamoto M. Muscular sarcoidosis: findings at MR imaging.  Radiology . 1990;  176 145-148
    PubMedGoogle Scholar
  • 5 Vanhoenacker P, Brijs S, Geusens E. MR imaging of primary muscular sarcoidosis. Case report.  Fortschr Roetgenstr . 1994;  161 570-571
    PubMedGoogle Scholar
  • 6 Matsuo M, Ehara S, Tamakawa Y. Muscular sarcoidosis.  Skeletal Radiol . 1995;  24 535-537
    PubMedGoogle Scholar
  • 7 Garcia O M, Sarma D. Gallium scanning in a patient with sarcoidosis.  Clin Nucl Med . 1983;  8 557
    PubMedGoogle Scholar
  • 8 Rohatgi P K, Singh R, Vieras F. Extrapulmonary localization of gallium in sarcoidosis.  Clin Nucl Med . 1987;  12 9-16
    PubMedGoogle Scholar
  • 9 Otake S, Imagumbai N, Suzuki M, Ohba S. MR imaging of muscular sarcoidosis after steroid therapy.  Eur Radiol . 1998;  8 1651-1653
    CrossrefPubMedGoogle Scholar
  • 10 Edan G, Bourguet P, Delaval P, Herry J Y. Gallium-67 imaging in muscular sarcoidosis.  J Nucl Med . 1984;  25 776-778
    PubMedGoogle Scholar
  • 11 Patel N, Krasnow A, Sebastian J L. Isolated muscular sarcoidosis causing fever of unknown origin: the value of gallium-67 imaging.  J Nucl Med . 1991;  32 319-321
    PubMedGoogle Scholar
  • 12 Liem I H, Drent M, Antevska E, Lamers R JS, Heidendal G AK. Intense muscle uptake of gallium-67 in a patient with sarcoidosis.  J Nucl Med . 1998;  39 1605-1607
    PubMedGoogle Scholar
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