Interventionelle Therapie von Lebermetastasen

 

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Zusammenfassung

Für die Behandlung von Lebermetastasen bietet die interventionelle Radiologie sowohl lokale wie lokoregionäre Therapiekonzepte an. Während lokale Konzepte als bildgeführte interstitielle Techniken eingesetzt werden, ist für die lokoregionäre Verteilung von antitumorösen Wirkstoffen der vaskuläre Zugang ideal. In diesem Artikel werden von den derzeit interstitiell eingesetzten Ablationsmethoden die Radiofrequenz, die laserinduzierte Thermotherapie und die CT-gesteuerte Brachytherapie anhand der verfügbaren Literatur bewertet. Aus dem Bereich der lokoregionär vaskulären Techniken finden sich Analysen der intraarteriellen Chemotherapie über minimalinvasiv implantierte Portsysteme sowie die transarterielle Chemoembolisation.

Abstract

Interventional radiology offers not only local but also loco-regional therapeutic concepts for the treatment of liver metastases. While the local concepts are employed as image-guided, interstitial techniques, a vascular access is ideal for the loco-regional distribution of anti-tumour drugs. In the present article interstitial employed ablation methods such as radiofrequency ablation, laser-induced thermotherapy and CT-guided brachytherapy are evaluated on the basis of the available literature. The field of loco-regional vascular techniques contributes analyses of intra-arterial chemotherapy via minimally invasively implanted port systems as well as transarterial chemoembolisation.

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Prof. Dr. J. Ricke

Klinik für Strahlenheilkunde, Charité Virchow-Klinikum

Augustenburger Platz 1

13353 Berlin

Phone: ++ 49/30/4 50 55 70 01

Fax: ++ 49/30/4 50 55 79 01

Email: jens.ricke@charite.de