Alterations of Lipid Metabolism in Men with Hypotestosteronemia

Melita Hromadová; T. Háčik; E. Malatinský; I. Riečanský

doi:10.1055/s-2007-1003708

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Horm Metab Res 1991; 23(8): 392-394
DOI: 10.1055/s-2007-1003708

Clinical

Alterations of Lipid Metabolism in Men with Hypotestosteronemia

Melita Hromadová¹ , T. Háčik¹ , E. Malatinský² , I. Riečanský³

¹Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava
²Clinical of Urology, University School of Medicine, Comenius University, Bratislava
³Institute of Cardiovascular Diseases, Bratislava, Czechoslovakia

Further Information

Publication History

1990

1991

Publication Date:
14 March 2008 (online)

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Summary

Studied relationship in serum concentration of testosterone and lipids in 35 men with a positive coronarographic finding and 30 sterile men, in comparison with a control group. From lipid parameters we determined serum concentration of cholesterol, triacylglycerols and apolipoprotein B, and lipid distribution in lipoprotein fractions.

Serum testosterone concentration was found decreased in both the group as against the controls. As to lipid parameters, cholesterol concentration was depressed in the high-density lipoprotein (HDL) fraction of both the clinical groups. As increased apolipoprotein B level was seen in men with the positive coronarographic finding.

The results point to a negative effect of lowered testosterone concentrations on lipid metabolism.

Key words

Oligospermia - Coronarosclerosis - Lipoproteins (VLDL, LDL, HDL, Cholesterol) - Triacylglycerols - Apolipoprotein-B - Testosterone

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