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J Reconstr Microsurg 1988; 4(4): 251-255
DOI: 10.1055/s-2007-1006928
ORIGINAL ARTICLE

© 1988 by Thieme Medical Publishers, Inc.

The Effects of Electrical Stimulation on Denervated Muscle Using Implantable Electrodes

Koichi Nemoto, H. Bruce Williams, Keiko Nemoto, John Lough, R. C.-J. Chiu
  • Montreal General Hospital, McGill University, Montreal, Quebec, Canada
Further Information

Publication History

Accepted for publication 1988

Publication Date:
08 March 2008 (online)

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ABSTRACT

This experimental study investigated the effects of continuous electrical stimulation on denervated muscle. The canine peroneal nerve was severed and repaired microsurgically, and the denervated extensor muscle group of the leg was stimulated continuously with an implantable electrode and pulse generator. EMG study muscle force measurement, muscle weight measurement, histology, and histochemistry were performed to study the effect at eight weeks after the operation. Continuous electrical stimulation (pulse frequency 130 pps, burst rate approximately 1 train/min) was effective in decreasing muscle atrophy and in improving muscle force. These findings may have broader clinical applications.

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