Download PDF
Am J Perinatol 1999; 16(4): 189-191
DOI: 10.1055/s-2007-993856
ORIGINAL ARTICLE

© 1999 by Thieme Medical Publishers, Inc.

Pregnancy and Renal Tubular Acidosis

Thomas E. Rowe1 , Kevin Magee2 , F. Gary Cunningham3
  • 1The University of Texas Medical Branch at Galveston, Department of Obstetrics and Gynecology, Galveston, Texas
  • 2Baylor University Medical Center, Department of Obstetrics and Gynecology
  • 3The University of Texas Southwestern Medical Center at Dallas, Department of Obstetrics and Gynecology, Dallas, Texas
Further Information

Publication History

Publication Date:
04 March 2008 (online)

    Permissions and Reprints

ABSTRACT

Renal tubular acidosis (RTA) is uncommonly encountered in pregnancy. The risk for these women to develop pregnancy-induced hypertension has not been previously described. The renal defect noted in these women, aggravated by the normal hyperv-olemia of pregnancy, may predispose to hypertension. Three pregnancies in two women with RTA type 1 developed persistent diastolic hypertension in the third trimester. Mild renal insufficiency was noted in each woman as defined by serum creati-nine of 0.9-1.1 and 1.4-1.6 mg/dL, respectively. Vaginal delivery was achieved in each without complications. Blood pressures returned to normal following each pregnancy. Pregnancy-induced hypertension developed in each of three pregnancies in two patients with RTA type 1. The risk for these women to develop pregnancy-induced hypertension may be associated with the higher reported risk in women with underlying renal disease.

Keywords

Renal tubular acidosis (RTA) - pregnancy

      >