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Am J Perinatol 1992; 9(4): 254-257
DOI: 10.1055/s-2007-994783
ORIGINAL ARTICLE

© 1992 by Thieme Medical Publishers, Inc.

Treatment of Neonatal Renovascular Hypertension with Intravenous Enalapril

Tom Mason, Mark J. Polak, Lee Pyles, Martha Mullett, Clare Swanke
  • Departments of Pediatrics, West Virginia School of Medicine, and the Department of Clinical Pharmacy, West Virginia University Children's Hospital, Morgantown, West Virginia
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Publication History

Publication Date:
04 March 2008 (online)

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ABSTRACT

Hypertension in the neonate is commonly related to renal disease. More specifically, renovascular hypertension in neonates is often associated with the placement of a umbilical artery catheter. Many medications, including angiotensin-converting enzyme (ACE) inhibitors, have been used in the treatment of neonatal hypertension. Captopril, an ACE inhibitor, is an oral agent that is effective in renovascular hypertension. We describe the use of intravenous enalapril, another ACE inhibitor, in successfully treating severe renovascular hypertension refractory to standard medical therapy in two term neonates.

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