Clinical Investigations: Interventional CardiologyPrevalence, predictors, and consequences of unrecognized diabetes mellitus in 3266 patients scheduled for coronary angiography☆,☆☆,★,★★
Section snippets
Methods
The Ludwigshafen Risk and Cardiovascular Health Study (LURIC)20 enrolled 3316 consecutive patients admitted for coronary angiography at the Ludwigshafen Heart Center between 1997 and 1999 to investigate traditional and new cardiovascular risk factors including various gene polymorphisms. Patients were enrolled after written informed consent. The study was approved by the ethics committee of the federal state of Rheinland Pfalz physicians' board (Landesärztekammer Rheinland-Pfalz).
After
Results
A total of 3266 patients fulfilled inclusion criteria of the LURIC study.
Discussion
In consecutive patients scheduled for coronary angiography, we observed as many patients with undiagnosed diabetes as patients with known diabetes, raising the proportion of patients with diabetes to about one third. Newly diagnosed diabetes is characterized by an intermediate coronary pathology and a borderline association with myocardial infarction. Screening for diabetes at this stage provides a unique opportunity for starting preventive efforts against the further diabetes-associated
Acknowledgements
The authors are indebted to B. Ksoll, S. Veth, N. Leonhardt, and A. Bilir for invaluable technical assistance.
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Supported in part by grants from the Deutsche Forschungsgemeinschaft (SFB 518) and the Deutsche Diabetesgesellschaft.
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Reprint requests: Gunnar Taubert, MD, Herzzentrum Ludwigshafen, Bremserstr. 79, 67063 Ludwigshafen, Germany.
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E-mail: [email protected]
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0002-8703/2003/$30.00 + 0