Solitary cutaneous myxoma,☆☆

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Abstract

We describe a case of a large pedunculated solitary cutaneous myxoma arising on the thigh of a 47-year-old man without evidence of Carney’s complex, NAME, or LAMB syndromes. The diagnosis was confirmed by hematoxylin and eosin stain, special stains, and immunocytochemistry studies. The tumor was surgically resected with no evidence of recurrence after 6 months. Solitary cutaneous myxoma should be differentiated histologically from myxoid neurofibroma, neurothekeoma, and ossifying and nonossifying fibromyxoid tumor. (J Am Acad Dermatol 2000;43:377-9.)

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Case report

A 47-year-old man complained of a mildly tender thigh mass, slowly enlarging over the past 2 years. The patient had no similar lesions elsewhere, and there was no family history of analogous lesions. Past history was significant for left leg varicose veins, venous insufficiency, and stasis dermatitis. There was no history of any endocrinopathy.

Examination of the left thigh revealed a 7 × 6 × 6 cm firm, pedunculated, skin-colored tumor with a papillomatous surface (Fig 1).

. Firm polypoid tumor on

Discussion

The SCM has been described as a “flesh colored, hairy nodule”2 or as a “soft, lobulated nodule that elevated the overlying skin to varying degrees.”1 Over the years, only a few reports of solitary or multiple cutaneous myxomas without any systemic features have emerged.2, 6

Multiple cutaneous myxomas have been generally ascribed to Carney’s complex,3 NAME,4 or LAMB5 syndromes. The cutaneous myxomas that accompany Carney’s complex generally affect young patients, and are usually less than 1 cm in

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This supplement is made possible through an educational grant from Ortho Dermatological to the American Academy of Dermatology.

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