Oral and Maxillofacial Surgery
Survey of congenital anomalies associated with cleft lip and/or palate in 701,181 Japanese people

https://doi.org/10.1067/moe.2001.112948Get rights and content

Abstract

There have been many reports on congenital anomalies associated with cleft lip and/or palate (CL/CLP) in Japan. However, these reports included data only on patients who came to hospitals; thus the real situation regarding these anomalies remains unclear. Therefore, we surveyed newborns at all delivery facilities in the central area of Japan for the presence of these anomalies, following their progress for 12 consecutive years; at the end of that time, questionnaires were collected and analyzed. In this article, we describe our results. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:157-61)

Section snippets

Method

Each delivery facility in the Tokai area informed us annually of its number of births, from which we conducted a survey of babies born with CL/CLP. This survey recorded the month of birth, sex, birth weight, and associated congenital anomalies of every baby with CL/CLP. The survey period was 12 years and covered 701,181 births, which accounted for 53.7% of the 1,305,030 births in this area. The main subjects of this survey were 1063 newborns with CL/CLP. Some birth weight records or details

Results

Table I provides an incidence order of the congenital anomalies.

Discussion

Although cases of congenital anomalies associated with CL/CLP have been reported by many hospitals, the data differ among hospitals. For example, many cases were from general hospitals that have neonatal intensive care units, whereas few patients with associated anomalies are introduced to the dental hospitals attached to universities like ours. Therefore, we investigated associated congenital anomalies in Japan by surveying child-delivery facilities. Although this method is effective for

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Reprint requests: Nagato Natsume, DDS, DMedSc, PhD, Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University, 1-22, Suemori-dori, Chikusa-ku, Nagoya, Japan 464-8651, [email protected]

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