Original ArticlesOutcome of ventricular septal defect repair in a developing country☆
Section snippets
Study design
The clinical records of 100 consecutive infants (age, ≤12 months) who underwent VSD closure at our institute between July 1998 and June 2000 were retrospectively reviewed.
Setting
The study was conducted in the setting of a tertiary care referral hospital serving a population of approximately 30 million people in the state of Kerala in southern India. Approval for retrospective chart review was obtained from the hospital's medical records division.
Patients
Consecutive infants at our institution who underwent
Results
The average age at the time of surgery was 7.4 ± 3.3 months (range, 1-12 months) (Table I); 44 patients were ≤6 months of age.Age (mo)* 7.4 ± 3.3 (1-12) Sex Male 58%, female 42% Weight at surgery (kg)* 5.2 ± 1.3 (2.5-9.0) Z score weight* −2.8 ± 1.3 (−5.6-3.3) Length at surgery (cm)* 64 ± 6.5 (49-94) Z score length* −1.9 ± 2.0 (−6.7-3.2) Associated syndromes Trisomy 21: 6%, others: 4% VSD number Single 94%, multiple 6% Restrictive VSD (VSD gradient >30
Discussion
There is little published information on the impact of preoperative conditions such as poor nutritional status and lung infection on postoperative outcome after open heart surgery in infants. The purpose of this retrospective study, conducted in a tertiary referral center in south India, was to determine whether severe malnutrition, recent lung infection, or younger age increased the morbidity and/or mortality rates of infants undergoing reparative surgery for large VSD(s).
The preoperative
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Reprint requests: R. Krishna Kumar, MD, Consultant Pediatric Cardiologist, Amrita Institute of Medical Sciences and Research Center, Kochi 682026, Kerala, India.