Journal of Biological Chemistry
PROTEIN STRUCTURE AND FOLDINGDecreased Metallation and Activity in Subsets of Mutant Superoxide Dismutases Associated with Familial Amyotrophic Lateral Sclerosis*210
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Published, JBC Papers in Press, February 19, 2002, DOI 10.1074/jbc.M112087200
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This work was supported by grants from the ALS Association (to L. J. H., J. S. V., and D. E. C.); National Institutes of Health Grants GM28222 (to J. S. V.) and PO1NS31248 and PO1NS37912 (to R. H. B.); the Angel Fund; the Al Athel Research Program; ProjectALS; the deBourgknecht ALS Fund; and the Cecil B. Day Neuromuscular Research Laboratory (to R. H. B.). Pulse radiolysis studies were conducted at Brookhaven National Laboratory under Contract DEAC02-98CH108816 with the United States Department of Energy, Division of Chemical Sciences, Office of Basic Energy Sciences.The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
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The on-line version of this article (available athttp://www.jbc.org) contains rotation animations for Fig. 1,A and B.