Journal of Biological Chemistry
Metabolism and BioenergeticsDifferential Metabolomics Reveals Ophthalmic Acid as an Oxidative Stress Biomarker Indicating Hepatic Glutathione Consumption*
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This work was supported in part by a grant from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) (the 21st Century COE Program entitled “Understanding and Control of Life's Function via Systems Biology,” and a grant from Grant-in-aid of Creative Researches and Leading Project for Biosimulation from MEXT in Japan as well as research funds from Yamagata prefectural government and Tsuruoka city. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
The on-line version of this article (available at http://www.jbc.org) contains supplemental data.
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These authors contributed equally to this work.