Timely topic: premalignant lesions associated with adenocarcinoma of the upper gastrointestinal tract
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Temporal trends of esophageal disorders by age in the Cerner Health Facts database
2016, Annals of EpidemiologyCitation Excerpt :Esophageal adenocarcinoma (EA) incidence has increased approximately 600% over the last 4 decades in the United States [2,3]. Gastroesophageal reflux disease (GERD) is characterized by reflux of gastric contents into the esophagus [4]. It is a common condition that is estimated to affect 10%–20% of adults in Western countries and can cause loss of the native squamous epithelium, followed by the development of Barrett's epithelium (BE) [5].
Dietary flavonoid intake and Barrett's esophagus in western Washington State
2015, Annals of EpidemiologyCitation Excerpt :However, because all existing studies conducted among BE patients have relied on an FFQ [12,38,39], a cohort study would be required, with employment of multiple alternative dietary assessment methods repeatedly over time, to overcome the limitations of existing studies. Such an alternative study design would be inefficient because only 10%–15% of symptomatic GERD patients develop BE in their lifetime [40]. Our study FFQ did not assess dietary supplement use.
HMGA1 is induced by Wnt/β-catenin pathway and maintains cell proliferation in gastric cancer
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2002, Current Problems in CancermiR-375-3p/YWHAZ/β-catenin axis regulates migration, invasion, EMT in gastric cancer cells
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