Case ReportsFulminant Stenotrophomonas maltophilia Soft Tissue Infection in Immunocompromised Patients: An Outbreak Transmitted via Tap Water
Section snippets
Case 1
A 31-year-old woman was admitted with fever, fatigue, and perianal pain of 1 week’s duration. Physical examination revealed a markedly pale patient without dyspnea or jaundice. Her temperature was 38°C, her blood pressure normal, and her heart rate was 110 beats/min. Her physical examination was normal except for hemorrhoids. Laboratory studies revealed leucocytosis of 35,300/mm3 with 89% blasts and 3% neutrophiles, hemoglobin of 8.4 g/dL, and platelet count of 351,000/mm3. Bone marrow biopsy and
Discussion
S maltophilia is increasingly recognized as an important pathogen causing nosocomial infections. A number of nosocomial outbreaks had been reported in the last years.6., 8., 9., 30., 31. Khardori et al6 reported an increased rate of isolation of S maltophilia in patients with cancer. From December 1985 to May 1986, 52 isolates of the organism were recovered from cultures of clinical specimens from 38 patients; case records were available for 35 of the 38 patients. Of these, 18 patients had a
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Cited by (67)
Waterborne infections in haemato-oncology units – a narrative review
2023, Journal of Hospital InfectionStenotrophomonas maltophilia outbreak originating from a pull-out faucet in a pediatric intensive care unit in Turkey: Insights from clinical records and molecular typing
2023, American Journal of Infection ControlStenotrophomonas maltophilia infections: Clinical characteristics in a military trauma population
2020, Diagnostic Microbiology and Infectious DiseaseCitation Excerpt :Despite this, serial isolation was a rare event, potentially due to surgical management. Being ubiquitous in the environment (Denton and Kerr 1998; Brooke 2012), this organism has been linked to nosocomial transmission via water sources, disinfectant solutions, and other healthcare-related modes of transmission (Khardori et al. 1990; Sakhnini et al. 2002; Mukhopadhyay et al. 2003), raising the suspicion that infections occur primarily through a common contaminated source. Nevertheless, our analysis showed no evidence for clonal spread, suggesting that trauma patients are acquiring unique healthcare-associated infections selected through antimicrobial pressure, again emphasizing the role for antimicrobial stewardship in these critically ill patients.
Physicochemical characterization and antimicrobial evaluation of gentamicin-loaded CaCO<inf>3</inf> nanoparticles prepared via microemulsion method
2016, Journal of Drug Delivery Science and TechnologyCitation Excerpt :Gentamicin sulfate, an aminoglycoside antibiotic, is used to treat many types of bacterial infections caused by Gram-negative Pseudomonas, Proteus and Serratia as well as the Gram-positive Staphylococcus [19–21]. It is administered for the treatment of bacterial infections in bone, respiratory and urinary tract, skin, soft tissue, stomach, blood, and heart [22–24]. Gentamicin is also useful against Yersinia pestis, its relatives, and Francisella tularensis [19–21].