Journal of the American Academy of Child & Adolescent Psychiatry
ORIGINAL ARTICLESubstance Abuse Prevalence and Comorbidity with Other Psychiatric Disorders among Adolescents with Severe Emotional Disturbances
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Principal component analysis of early alcohol, drug and tobacco use with major depressive disorder in US adults
2018, Journal of Psychiatric ResearchCitation Excerpt :The present results further added that the prevalence of MDD decreased with age (9.2%, 7.4%, 7.1% and 2.8% for age groups 18–25, 26–49, 50–64 and 65+, respectively), which are similar to the results that the 12-month MDD from adults aged 55 years and older were 4.1% (2.1% for 65–74 and 5.5% for 75+) (Aranda et al., 2012). Being consistent with the findings in the previous studies, our results (Table 5) showed the adjusted OR of illicit drug or alcohol abuse or dependence with MDD was 2.32 (95% CI = 2.05–2.63), suggesting that alcohol use disorder or illicit drug dependence was associated with depression (Greenbaum et al., 1991; Grant and Harford, 1995; Brooner et al., 1997; Merikangas et al., 1998; Gilman and Abraham, 2001; Hasin and Grant, 2002; Sullivan et al., 2005; Miguel-Hidalgo et al., 2010; Boden and Fergusson, 2011; Grant et al., 2016; Han et al., 2017). For example, 12-month DSM-V drug use disorder (DUD) was found to be significantly associated with MDD (OR = 1.3; 95% CI = 1.09–1.64)(Grant et al., 2016).
Violent conflict and opiate use in low and middle-income countries: A systematic review
2014, International Journal of Drug PolicyThe moderating effect of family involvement on substance use risk factors in adolescents with severe emotional and behavioral challenges
2013, Addictive BehaviorsCitation Excerpt :Moreover, approximately 7.3% of 12- to 17-year-olds are diagnosed with substance use disorders (SAMHSA, 2012), indicating that a substantial percentage of adolescents are also experiencing serious problems as a result of their substance use. Research indicates that children and adolescents with severe emotional and behavioral challenges (SEB) are at greater risk for problematic substance use and receiving a substance use disorder diagnosis (e.g., Greenbaum, Prange, Friedman, & Silver, 1991). Further, rates of comorbid psychiatric disorders among adolescents with a substance use disorder are as high as 60% (Armstrong & Costello, 2002).
Are early-onset cannabis smokers at an increased risk of depression spells?
2012, Journal of Affective DisordersCitation Excerpt :Depression is a complex disorder, with many possible component causes. One avenue of research has focused on substance use disorders, which have been found to be co-morbid with depression in clinical and epidemiological samples (Brooner et al., 1997; Grant, 1995; Greenbaum et al., 1991; Merikangas et al., 1998). Inquiry into a connection between depression and specific psychoactive drug compounds has focused largely on tobacco (Breslau et al., 1991; Glassman et al., 1990; Kendler et al., 1993) and alcohol (Boden and Fergusson, 2011; Gilman and Abraham, 2001; Hasin and Grant, 2002), with cannabis to a much lesser extent (see review by Degenhardt et al., 2003).
Genetic and environmental influences on externalizing behavior and alcohol problems in adolescence: A female twin study
2009, Pharmacology Biochemistry and BehaviorIllicit drug-related psychopharmacological violence: The current understanding within a causal context
2009, Aggression and Violent BehaviorCitation Excerpt :This study is particularly important for purposes of the present research because it suggests genetic influences between early aggressiveness, antisocial personality disorder (which has been linked to violence), and later substance abuse. Other research has documented relationships between alcohol or marijuana abuse and conduct disorder and depression, controlling for a number of demographic variables, although the subjects were severely emotionally disturbed youth (Greenbaum, Prange, Friedman, & Starr, 1991). It is also well known that certain regions in the brain, that are stimulated by many different drugs, also control emotional responses which include impulsiveness, aggressiveness, fear or fearlessness, anxiety, and sensation-seeking, each of which has been linked to aggression (see Fishbein, 1991 for a lengthy discussion).
Supported by Grant H133B90004-01 from the National Institute on Disability and Rehabilitation Research and the National Institute of Mental Health. The authors thank Eric C. Brown for assistance in data analysis and Sharon P. Lardieri, Mike Bevill, Aaron Brie, AI Duchnowski, Maria Duchnowski, Marvin Eisen, Kelly Enzor-Kise, Sue Greer, Bob Haas, Jini Hanjian, Holly Hons, Krista Kutash, and Bradley Sickles for assistance in data collection.