Regular Research ArticlesPassive Body Heating Ameliorates Sleep Disturbances in Patients With Vascular Dementia Without Circadian Phase-Shifting
Section snippets
Participants
Subjects of the present study were 2 men and 11 women over age 70 (mean age, 76.9 years). Informed consent to participate was obtained from each subject or his/her family. All subjects had been residents of the same facility for elderly patients for at least 3 months before participating in the study. They all met DSM-IV criteria for vascular dementia. All subjects underwent brain magnetic resonance imaging; all subjects exhibited multiple lacunes, mainly occurring in basal ganglia, and deep
Effects of PBH on Sleep Quality
Properties of sleep quality in the baseline and PBH periods are shown in Table 1. PBH for 2 consecutive days induced a significant reduction in SL compared with the corresponding values in the baseline period. Changes in TST, SE, and WASO did not reach statistically significant levels. However, when sleep parameters were analyzed separately for the first and second halves of sleep time, repeated-measures ANOVA showed that PBH induced a significant increase in SE (F[2, 36] = 4.42; p = 0.020) and
DISCUSSION
This study provides data indicating that PBH exhibited therapeutic effects on both difficulty in sleep-initiation and decreased sleep-maintenance ability in our study subjects. Despite the shortcoming that this was an open study, the present findings support the notion that PBH could be an effective tool for sleep disturbance in elderly persons with mild vascular dementia, as it was shown to be in elderly IPs without dementia.3 PBH induced an acute and transient cBT elevation of approximately
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This study was supported by Special Coordination Funds of the Ministry of Education, Culture, Sports, and Technology, and a Grant-in-Aid for Cooperative Research from the Ministry of Health, Labor, and Welfare of Japan.