High reproducibility of histological diagnosis of human papillomavirus-related intraepithelial lesions of the anal canal
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Cited by (13)
HPV-associated disease of the anal canal: A pathology primer
2017, Seminars in Colon and Rectal SurgeryCitation Excerpt :Thus, improved interobserver agreement for the diagnosis of HSIL is seen with the conjunctive use of p16 immunostains with H&E morphology.32 LAST׳s recommendations for p16 use lead to improved accuracy and reproducibility of histologic diagnoses of precancer.33–35 In essence, the use of p16 immunostaining helps “polish the histologic gold standard” that informs patient management.36
Prevalence and risk factors associated with high-grade anal squamous intraepithelial lesions (HSIL)-AIN2 and HSIL-AIN3 in homosexual men
2016, Papillomavirus ResearchCitation Excerpt :In addition, biopsy reporting was performed in accordance with the LAST Project [13], limiting potential misclassification of histological HSIL. Also, there was a very high degree of inter-rater reliability and intra-rater repeatability in histological diagnosis in the study [35]. Finally, the limited sensitivity of anal cytology and HRA to detect HSIL was addressed by using a composite cytology-histology endpoint.
Diagnostic Pathology: Gastrointestinal
2015, Diagnostic Pathology: GastrointestinalClassifying Anal Intraepithelial Neoplasia 2 Based on LAST Recommendations
2021, American Journal of Clinical PathologyThe Natural History of Anal High-grade Squamous Intraepithelial Lesions in Gay and Bisexual Men
2021, Clinical Infectious Diseases