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Psychosis related to methadone withdrawal

Published online by Cambridge University Press:  24 June 2014

Jesús Cobo ,
María Mar Ramos ,
Trinidad Peláez ,
Gemma García  and
Frederik Marsal
Jesús Cobo*
Affiliation:
Psychiatric Adults Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain
María Mar Ramos
Affiliation:
Psychiatric Adults Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain
Trinidad Peláez
Affiliation:
Psychiatric Adults Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain
Gemma García
Affiliation:
Psychiatric Adults Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain
Frederik Marsal
Affiliation:
Psychiatric Adults Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain
*
Dr Jesús Cobo, Psychiatric Adults and Detoxification Unit, Corporació Hospitalària Parc Taulí, Parc Taulí s.n., 08208 Sabadell, Barcelona, Spain. Tel: +34 93 7458350; Fax: +34 93 7458349; E-mail: jcobo@cspt.es
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Abstract

We present two cases of typical psychosis related to methadone withdrawal. The two cases, appearing in the adult age, are not related to previous personal or familiar psychiatric illness and do not show the classical symptoms of methadone withdrawal. The appearance of this type of case is an experience repeated in different groups of researchers. In the line of previous investigators, we propose an alteration of neuromodulation in central opiate-dopamine system.

Keywords

psychosismethadone withdrawalopiate-dopamine system
Type
Case Report
Information
Acta Neuropsychiatrica , Volume 18 , Issue 1 , February 2006 , pp. 50 - 51
Copyright
Copyright © 2006 Blackwell Munksgaard

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