Official Communication of the SSC and supporting review
Definition of post-thrombotic syndrome of the leg for use in clinical investigations: a recommendation for standardization

https://doi.org/10.1111/j.1538-7836.2009.03294.xGet rights and content
Under an Elsevier user license
open archive

Summary

The post-thrombotic syndrome (PTS) is increasingly recognized to be a common and important complication of deep venous thrombosis (DVT). Because there is no ‘gold standard’ objective test to establish its presence, PTS is diagnosed primarily on the basis of the presence of typical symptoms and clinical signs in a limb that was affected by DVT. As a wide variety of definitions of PTS have been used by researchers, it is difficult to compare data across studies and to formally combine data in meta-analyses. In a step towards standardization of the measurement of PTS in clinical studies, available scales and evidence to support their utility to diagnose PTS and to classify its severity were reviewed and discussed at the Control of Anticoagulation Subcommittee of the International Society on Thrombosis and Haemostasis (Vienna, July 2008).

Keywords

clinical diagnosis
clinical trials
deep venous thrombosis
definition
post-thrombotic syndrome
venous thromboembolism

Cited by (0)