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Laser heating of biological tissue with blood vessels: Modeling and clinical trials

  • Geometrical and Applied Optics
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Abstract

The spatial distribution of the energy absorbed by a unit volume of a laser-irradiated biological tissue is calculated by the Monte Carlo method. Based on these calculations, the temperature fields in biological tissues subjected to laser radiation at 810 nm are modeled. The temperature fields in subcutaneous blood vessels are modeled separately taking into account the inhomogeneous volumetric distribution of heat sources inside the vessels. The results of the modeling showed that laser heating can be efficiently used both for small-diameter and large vessels. Experimental clinical trials of therapy of vascular skin changes by pulsed diode laser radiation (at 810 nm) confirmed these results.

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Authors and Affiliations

  1. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, 220072, Belarus

    L. G. Astafyeva & G. P. Ledneva

  2. Institut für Physikalische Chemie, Universität Jena, D-07743, Jena, Germany

    R. Gade

  3. Gesellschaft für Medizin, Biologie und Umwelttechnologie e.V. Jena, D-07745, Jena, Germany

    W. -D. Schmidt & D. Fassler

  4. Department of Dermatology, Academic Teaching Hospital Dresden-Friedrichstadt, D-01067, Dresden, Germany

    U. Wollina

Authors
  1. L. G. Astafyeva
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  2. R. Gade
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  3. W. -D. Schmidt
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  4. G. P. Ledneva
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  5. U. Wollina
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  6. D. Fassler
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Original Russian Text © L.G. Astafyeva, R. Gade, W.-D. Schmidt, G.P. Ledneva, U. Wollina, D. Fassler, 2006, published in Optika i Spektroskopiya, 2006, Vol. 100, No. 5, pp. 855–863.

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Astafyeva, L.G., Gade, R., Schmidt, W.D. et al. Laser heating of biological tissue with blood vessels: Modeling and clinical trials. Opt. Spectrosc. 100, 789–796 (2006). https://doi.org/10.1134/S0030400X06050213

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  • DOI: https://doi.org/10.1134/S0030400X06050213

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