Purpose: To examine the effect of immediate irrigation on ocular alkali burn. Methods: Information on the injury, immediate irrigation, and ocular findings was retrospectively obtained from each patient’s record. Results: 36 patients (49 eyes) irrigated their eyes with tap water (the irrigation group) and 17 patients (29 eyes) did not (no irrigation group). The mean age of patients in the irrigation and no irrigation groups was 30 and 53 years, respectively. According to Hugher’s classification, 76% of eyes in the irrigation group had grade 1 injury, while 86% of eyes in the no irrigation group had grade 2 injuries. Mean time from the injury until healing was 8 days in the irrigation group and 29 days in the no irrigation group, respectively. Conclusion: Immediate copious irrigation with tap water reduced the severity in alkali burns of the eye and shortened the healing time.

1.
Hughes WF: Alkali burns of the cornea. I. Review of the literature and summary of present knowledge. Arch Ophthalmol 1946;35:423–426.
2.
Hughes WF Jr: Alkali burns of the eye. II. Clinical and pathologic course. Arch Ophthalmol 1946;36:189–214.
3.
Roper-Hall MJ: Thermal and chemical burns. Trans Ophthalmol Soc UK 1965;85:631–653.
4.
Klein R, Lobes LA Jr: Ocular alkali burns in a large urban area. Ann Ophthalmol 1976;8:1185–1189.
5.
Thoft RA: Chemical and thermal injury. Int Ophthalmol Clin 1979;95:243–256.
6.
Pfister RR: Chemical injuries of the eye. Ophthalmology 1983;90:1246–1253.
7.
Morgan SJ: Chemical burns of the eye: causes and management. Br J Ophthalmol 1987;71:854–857.
8.
Beare JD: Eye injuries from assault with chemicals. Br J Ophthalmol 1990;74:514–518.
9.
Saini JS, Sharma A: Ocular chemical burns: clinical and demographic profile. Burns 1993;19:67–69.
10.
Kuckelkorn R, Luft I, Kottek AA, Schrage NF, Makropoulos W, Reim M: Chemical and thermal eye burns in the residential area of the RWTH Aachen. Klin Monatsbl Augenheilkd 1993;203:34–42.
11.
Kuckelkorn R, Makropoulos W, Kottek A, Reim M: Retrospective study of severe alkali burns of the eye. Klin Monatsbl Augenheilkd 1993;203:397–402.
12.
Wagoner MD, Kenyon KR: Chemical injuries of the eye; in Albert DM, Jacobiec FA (eds): Principles and Practice of Ophthalmology. Philadelphia, Saunders, pp 234–245.
13.
Kuckelkorn R, Kottek A, Schrage N, Reim M: Poor prognosis of severe chemical and thermal eye burns: the need for adequate emergency care and primary prevention. Int Arch Occup Environ Health 1995;67:281–284.
14.
Wagoner MD: Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol 1997;41:275–313.
15.
Schrage NF, Langefeld S, Zschocke J, Kuckelkorn R, Redbrake C, Reim M: Eye burns: an emergency and continuing problem. Burns 2000;26:689–699.
16.
Burns FR, Paterson CA: Prompt irrigation of chemical eye injuries may avert severe damage. Occup Health Safety 1989;58:33–36.
17.
Goldberg MF, Bron AJ: Limbal palisades of Vogt. Trans Am Ophthalmol Soc 1982;80:155–171.
18.
Kurome H, Hayasaka S, Yamada Y, Setogawa T: A case of corneal alkali burn by ammonia solution for treatment of acid burn of the face and neck (in Japanese). Ganka Rinsho Iho 1994;88:741–742.
19.
Herr RD, White GL Jr, Bernhisel K, Mamalis N, Swanson E: Clinical comparison of ocular irrigation fluids following chemical injury. Am J Emerg Med 1991;9:228–231.
20.
Pfister RR, Haddox JL, Yuille-Barr D: The combined effect of citrate/ascorbate treatment in alkali-injured rabbit eyes. Cornea 1991;10:100–104.
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