Background
Methods
The population
The HUNT 2 study
Headache diagnoses
Chronic musculoskeletal complaints (CMSCs)
The definition of insomnia-free in HUNT 2
The HUNT 3 study
Insomnia diagnosis
Headache
Study population
Ethics
Statistics
Results
Variables | |
---|---|
Number of participants | 19,271 |
Age (mean [SD], missing = 0) | 45.8 [12.7] |
Gender (% women, missing = 0) | 54.7 |
Married (%, missing = 12) | 69.4 |
Education ≥ 13 years (%, missing = 275) | 35.6 |
Paid work (%, missing = 167) | 73.6 |
High level of physical activity2 (%, missing = 4150) | 9.7 |
BMI (mean [SD], missing = 35) | 26.0 [3.8] |
Systolic BP (mean [SD], missing = 46) | 133.3 [18.4] |
Daily use of tobacco (%, missing = 1857) | 27.2 |
Alcohol overuse (cage score ≥ 1) (%, missing = 2287) | 16.2 |
Total HADS-score (mean [SD], missing = 1978) | 6.6 [4.7] |
GI-complaints3 (%, missing 517) | 48.5 |
Headache
Both gender
1
| Women
2
| Men
2
| |||||
---|---|---|---|---|---|---|---|
Insomnia
3
| Insomnia
3
| Insomnia
3
| |||||
n, total = 14,639 | n = 3069 | OR (95% CI) | n = 2020 | OR (95% CI) | n = 1049 | OR (95% CI) | |
No headache or CMSCs
|
7263
|
1080
|
1.0 (ref)
|
581
|
1.0 (ref)
|
499
|
1.0 (ref)
|
Headache4
| 7376 | 1989 | 1.7 (1.6 – 1.9) | 1439 | 1.8 (1.6 – 2.0) | 550 | 1.7 (1.4 – 1.9) |
< 7 days / month | 6202 | 1589 | 1.7 (1.5 – 1.8) | 1142 | 1.7 (1.5 – 1.9) | 447 | 1.6 (1.4 – 1.8) |
≥ 7 days / month | 1174 | 400 | 2.2 (1.9 – 2.6) | 297 | 2.2 (1.8 – 2.7) | 103 | 2.2 (1.7 – 2.8) |
p-trend | <0.001 | <0.001 | <0.001 | ||||
Non migraineous headache | 4963 | 1278 | 1.7 (1.5 – 1.8) | 884 | 1.7 (1.5 – 1.9) | 394 | 1.6 (1.4 – 1.9) |
< 7 days / month | 4279 | 1049 | 1.6 (1.4 – 1.8) | 726 | 1.6 (1.4 – 1.8) | 323 | 1.6 (1.3 – 1.8) |
≥ 7 days / month | 684 | 229 | 2.2 (1.8 – 2.7) | 158 | 2.2 (1.7 – 2.8) | 71 | 2.3 (1.6 – 3.1) |
p-trend | <0.001 | <0.001 | <0.001 | ||||
Migraine | 2413 | 711 | 1.9 (1.7 – 2.1) | 555 | 2.0 (1.7 – 2.3) | 156 | 1.7 (1.4 – 2.1) |
< 7 days / month | 1923 | 540 | 1.8 (1.6 – 2.1) | 416 | 1.9 (1.6 – 2.2) | 124 | 1.6 (1.3 – 2.1) |
≥ 7 days / month | 490 | 171 | 2.2 (1.7 – 2.7) | 139 | 2.2 (1.7 – 2.9) | 32 | 2.0 (1.3 – 3.1) |
p –trend | <0.001 | <0.001 | <0.001 |
Chronic musculoskeletal complaints
Both gender
1
| Women
2
| Men
2
| |||||
---|---|---|---|---|---|---|---|
Insomnia
3
| Insomnia
3
| Insomnia
3
| |||||
n, total = 15,604 | n = 3372 | OR (95% CI) | n = 2025 | OR (95% CI) | n = 1347 | ||
No headache or CMSCs
|
7263
|
1080
|
1.0 (ref)
|
581
|
1.0 (ref)
|
499
|
1.0 (ref)
|
CMSCs4
| 8341 | 2292 | 1.8 (1.6 – 1.9) | 1444 | 1.9 (1.6 – 2.1) | 848 | 1.7 (1.5 – 1.9) |
Non widespread CMSC | 4219 | 992 | 1.6 (1.4 – 1.7) | 584 | 1.6 (1.4 – 1.9) | 408 | 1.5 (1.3 – 1.8) |
Widespread5 CMSC | 4122 | 1300 | 2.0 (1.8 – 2.2) | 860 | 2.1 (1.8 – 2.4) | 440 | 1.9 (1.6 – 2.2) |
Combined headache and chronic musculoskeletal complaints
Pure headache (no CMSCs) | Coexisting headache and CMSCs | |||||
---|---|---|---|---|---|---|
Insomnia
1
|
Insomnia
1
| |||||
total, n = 10,775 | n = 1896 | OR (95% CI) | total, n = 11,127 | n = 2283 | OR (95% CI) | |
No headache or CMSCs
|
7263
|
1080
|
1.0 (ref)
|
7263
|
1080
|
1.0 (ref)
|
Headache | 3512 | 786 | 1.5 (1.3 – 1.6) | 3864 | 1203 | 2.0 (1.8 – 2.2)* |
< 7 days / month | 3141 | 669 | 1.4 (1.2 – 1.6) | 3061 | 920 | 1.9 (1.7 – 2.2)* |
≥ 7 days / month | 371 | 117 | 2.1 (1.7 – 2.7) | 803 | 283 | 2.2 (1.9 – 2.7) |
p-trend | <0.001 | <0.001 | ||||
Non migraineous headache | 2437 | 512 | 1.4 (1.2 – 1.5) | 2526 | 766 | 2.0 (1.7 – 2.2)* |
< 7 days / month | 2221 | 443 | 1.3 (1.1 – 1.5) | 2058 | 606 | 1.9 (1.6 – 2.2)* |
≥ 7 days / month | 216 | 69 | 2.2 (1.6 – 3.0) | 468 | 160 | 2.2 (1.8 – 2.8) |
p-trend | <0.001 | <0.001 | ||||
Migraine | 1075 | 274 | 1.7 (1.5 – 2.0) | 1338 | 437 | 2.0 (1.7 – 2.3) |
< 7 days / month | 920 | 226 | 1.7 (1.4 – 2.0) | 1003 | 314 | 1.9 (1.7 – 2.3) |
≥ 7 days / month | 155 | 48 | 2.1 (1.5 – 3.0) | 335 | 123 | 2.2 (1.7 – 2.8) |
p –trend | <0.001 | <0.001 |
Pure CMSCs (no headache) | CMSCs & headache < 7d / month | CMSCs & headache ≥7d / month | |||||||
---|---|---|---|---|---|---|---|---|---|
Insomnia
1
|
Insomnia
1
|
Insomnia
1
| |||||||
N, total = 11,558 | N, total = 2109 | OR (95% CI) | N, total = 10,324 | N, total = 2000 | OR (95% CI) | N, total = 8066 | OR (95% CI) | ||
No headache or CMSCs
|
7263
|
1080
|
1.0 (ref)
|
7263
|
1080
|
1.0 (ref)
|
7263
|
1080
|
1.0 (ref)
|
CMSCs2
| 4295 | 1029 | 1.6 (1.4 – 1.7) | 3061 | 920 | 1.9 (1.7 – 2.2) | 803 | 283 | 2.2 (1.9 – 2.6)* |
Non-widespread CMSCs | 2513 | 540 | 1.4 (1.3 – 1.6) | 1357 | 339 | 1.6 (1.4 – 1.9) | 262 | 86 | 2.2 (1.7 – 3.0)* |
Widespread3 CMSCs | 1782 | 489 | 1.8 (1.5 – 2.0) | 1704 | 581 | 2.2 (1.9 – 2.5) | 541 | 197 | 2.2 (1.8 – 2.7) |