Background
Methods
Setting
Sampling and recruitment
Study instruments
Ethical consideration
Statistical analysis
Results
Characteristics of the study sample
Characteristic | No. | % |
---|---|---|
Age n = 239
| ||
≤50 year
|
137
|
57.3
|
>50 years
|
102
|
42.7
|
Time since diagnosis n = 239
| ||
Early diagnosed
|
35
|
14.6
|
Transitional period
|
128
|
53.6
|
Long term survivors
|
76
|
31.8
|
Educational level n = 236
| ||
Illiterate
|
60
|
25.4
|
Primary
|
30
|
12.7
|
Intermediate
|
23
|
9.7
|
High school/diploma
|
81
|
34.4
|
College graduate
|
42
|
17.8
|
Employment n = 236
| ||
Yes
|
50
|
21.2
|
No
|
146
|
61.9
|
Retired
|
40
|
16.9
|
Monthly income n = 235
<500
|
132
|
56.2
|
500–1000
|
57
|
24.3
|
> 1000
|
46
|
19.5
|
Menopausal status n = 236
| ||
Premenopause
|
110
|
46.6
|
Perimenopause
|
36
|
15.3
|
Postmenopause
|
90
|
38.1
|
Pathological staging n = 134
| ||
Stage 0 and I
|
40
|
29.9
|
Stage II
|
60
|
44.8
|
Stage III and IV
|
34
|
25.3
|
Distant metastasis n = 236
| ||
Yes
|
17
|
7.2
|
No
|
219
|
92.8
|
Treatment modality n = 236
| ||
Lumpectomy
|
121
|
51.3
|
Mastectomy
|
118
|
50.0
|
Lymph node dissection
|
200
|
85.1
|
Chemotherapy
|
190
|
80.5
|
Radiotherapy
|
198
|
83.9
|
Hormonal therapy
|
164
|
69.8
|
Profile of quality of life scale scores
Variables | N | No. of items | Mean (SD) | 95% CI | N (%) scoring <33.3)a
| N (%) scoring ≥66.7)a
|
---|---|---|---|---|---|---|
QLQ-C30
| ||||||
Global health status/QoL
|
238
|
2
|
63.93(21.34)
|
61.21-66.66
|
13(5.4)
|
92(38.5)
|
Functional scales
b
| ||||||
Physical functioning
|
239
|
5
|
74.92(21.69)
|
72.15-77.68
|
9(3.8)
|
154(64.4)
|
Role functioning
|
237
|
2
|
68.84(35.96)
|
64.24-73.44
|
33(13.8)
|
132(55.2)
|
Emotional functioning
|
236
|
4
|
63.41(33.46)
|
59.12-67.71
|
52(21.8)
|
118(49.4)
|
Cognitive functioning
|
238
|
2
|
73.38(29.87)
|
69.57-77.20
|
24(10.0)
|
140(58.6)
|
Social functioning
|
238
|
2
|
77.52(30.27)
|
73.65-81.38
|
21(8.8)
|
152(63.6)
|
Symptom scales
c
| ||||||
Fatigue
|
239
|
3
|
35.28(30.62)
|
31.38-39.18
|
117(49.0)
|
39(16.3)
|
Nausea and vomiting
|
238
|
2
|
10.29(30.77)
|
6.36-14.22
|
208(87.0)
|
9(3.8)
|
Pain
|
238
|
2
|
29.97(31.23)
|
25.98-33.96
|
135(56.5)
|
31(13.0)
|
Dyspnoea
|
239
|
1
|
20.22(30.32)
|
16.35-24.08
|
149(62.3)
|
15(6.3)
|
Sleep disturbance
|
239
|
1
|
30.12(39.29)
|
25.11-35.13
|
136(56.9)
|
42(17.6)
|
Appetite loss
|
239
|
1
|
13.38(27.62)
|
9.86-16.90
|
185(77.4)
|
11(4.6)
|
Constipation
|
239
|
1
|
17.99(30.66)
|
14.08-21.89
|
163(68.2)
|
18(7.5)
|
Diarrhea
|
239
|
1
|
6.83(18.95)
|
4.41-9.24
|
205(85.8)
|
4(1.7)
|
Financial impact
|
239
|
1
|
34.58(42.26)
|
29.20-39.97
|
130(54.4)
|
57(23.8)
|
QLQ-BR23
| ||||||
Functional scales
b
| ||||||
Body image
|
234
|
4
|
75.64(29.86)
|
71.79-79.48
|
24(10.0)
|
160(66.9)
|
Sexual functioning
|
234
|
2
|
25.92(29.77)
|
70.23-77.90
|
10(4.2)
|
129(54.0)
|
Sexual enjoyment
|
116
|
1
|
48.56(32.12)
|
45.52-57.34
|
16(6.7)
|
23(9.6)
|
Future perspective
|
236
|
1
|
61.29(39.37)
|
56.25-66.34
|
43(18.0)
|
105(43.9)
|
Symptom scales
c
| ||||||
Systemic side effect
|
236
|
7
|
19.27(17.76)
|
16.98-21.55
|
187(78.2)
|
4(1.7)
|
Breast symptoms
|
236
|
4
|
13.66(18.06)
|
11.34-15.98
|
195(81.6)
|
4(1.7)
|
Arm symptoms
|
236
|
3
|
36.58(31.76)
|
32.50-40.65
|
113(47.3)
|
34(14.2)
|
Upset by hair loss
|
100
|
1
|
46.33(42.87)
|
37.82-54.84
|
38(15.9)
|
32(13.4)
|
Factors associated with QoL scale scores
Global health and Functional scale in QLO-C30
Characteristic | Global health /QoL Mean(SD) | Functional scales in QLQ-C30b
| ||||
---|---|---|---|---|---|---|
Physical functioning Mean(SD) | Role functioning Mean (SD) | Emotional functioning Mean (SD) | Cognitive functioning Mean (SD) | Social functioning Mean (SD) | ||
Age | ||||||
≤50 year | 67.7(20.04) | 77.37(20.47) | 69.97(37.06) | 60.30(33.32) | 70.31(30.42) | 76.03(32.89) |
>50 years | 58.90(22.07) | 71.63(22.91) | 67.32(34.55) | 67.57(33.37) | 77.55(28.71) | 79.53(26.33) |
P-value | 0.147 | 0.271 | 0.176 | 0.710 | 0.412 | 0.005 |
Time since diagnosis | ||||||
Early diagnosed | 61.66(27.20) | 74.09(24.02) | 58.82(40.04) | 55.00(38.57) | 70.95(32.92) | 70.47(39.41) |
Transitional period | 62.76(20.99) | 73.69(21.30) | 66.66(36.06) | 64.37(33.02) | 74.93(29.76) | 76.37(28.90) |
Long term survivors | 67.00(18.65) | 77.36(21.30) | 76.97(32.54) | 65.76(31.44) | 71.92(28.83) | 82.67(27.14) |
P-value | 0.478 | 0.400 | 0.034 | 0.461 | 0.574 | 0.179 |
Marital status | ||||||
Single | 68.11(18.05) | 73.91(23.69) | 61.59(40.95) | 59.78(39.22) | 69.56(31.24) | 66.66(41.43) |
Married | 65.56(19.97) | 77.83(17.98) | 70.96(34.17) | 63.95(32.00) | 74.84(28.92) | 81.04(25.86) |
Divorced | 58.33(27.34) | 62.85(29.31) | 50.00(44.61) | 55.95(38.31) | 57.14(34.41) | 70.23(37.65) |
Widowed | 56.04(24.45) | 67.50(28.08) | 69.58(36.57) | 66.04(35.37) | 75.41(30.65) | 71.79(35.28) |
P-value | 0.041 | 0.123 | 0.216 | 0.780 | 0.205 | 0.371 |
Educational level | ||||||
Illiterate | 61.25(24.29) | 73.11(21.85) | 67.77(33.59) | 75.00(30.66) | 78.24(28.74) | 77.40(24.32) |
Primary | 54.16(25.21) | 60.66(27.14) | 57.77(42.82) | 54.72(32.65) | 75.55(30.86) | 77.22(30.47) |
Intermediate | 68.56(23.13) | 78.55(23.09) | 64.39(42.81) | 65.94(36.31) | 71.73(33.87) | 71.01(38.34) |
High school | 66.87(17.12) | 79.17(18.63) | 73.04(33.18) | 59.77(34.25) | 71.19(29.46) | 79.21(33.17) |
College graduate | 65.27(65.27) | 76.34(76.34) | 70.73(70.73) | 58.33(58.33) | 69.44(69.44) | 77.38(77.38) |
P -value | 0.059 | 0.009 | 0.548 | 0.009 | 0.284 | 0.535 |
Employment | ||||||
Yes | 67.83(15.88) | 76.53(21.81) | 73.00(36.24) | 60.20(32.46) | 72.00(29.82) | 78.00(31.66) |
No | 62.47(23.53) | 73.51(21.89) | 65.52(36.75) | 64.00(33.58) | 73.44(30.26) | 74.48(30.68) |
Retired | 62.91(18.58) | 76.83(21.08) | 74.12(32.58) | 64.37(35.45) | 74.16(29.46) | 87.08(26.00) |
P-value | 0.428 | 0.516 | 0.196 | 0.559 | 0.924 | 0.024 |
Monthly income | ||||||
<500 | 60.55(23.06) | 71.46(23.62) | 63.61(36.96) | 62.05(34.81) | 72.39(30.22) | 71.75(32.61) |
500–999 | 67.10(17.35) | 78.59(18.88) | 69.34(37.16) | 65.02(32.54) | 75.73(29.22) | 79.82(30.00) |
>1000 | 68.47(19.79) | 79.13(17.92) | 82.60(27.65) | 64.13(32.00) | 72.82(30.70) | 90.94(17.46) |
P-value | 0.036 | 0.087 | 0.005 | 0.974 | 0.818 | 0.001 |
Menopausal status | ||||||
Premenopause | 67.20(20.32) | 76.84(20.34) | 67.43(37.60) | 59.49(34.30) | 69.54(31.75) | 74.24(33.45) |
Perimenopause | 67.82(16.07) | 77.77(20.15) | 71.75(35.37) | 62.96(33.65) | 69.90(30.03) | 83.79(28.86) |
Postmenopause | 57.77(23.19) | 70.88(23.51) | 68.51(34.74) | 67.97(32.41) | 79.21(26.74) | 78.65(26.58) |
P-value | 0.016 | 0.142 | 0.831 | 0.123 | 0.057 | 0.268 |
Pathological staging | ||||||
Stage 0 and I | 66.87(17.65) | 74.33(22.26) | 66.66(36.98) | 59.58(31.72) | 69.58(32.66) | 82.08(28.59) |
Stage II | 65.55(23.14) | 74.55(23.43) | 69.49(35.17) | 64.58(32.92) | 77.50(28.59) | 72.31(30.88) |
Stage III and IV | 58. 08 (26.47) | 68.23(23.60) | 50.98(41.83) | 53.67 (37.67) | 67.15 (28.86) | 65.68(34.55) |
P-value | 0.295 | 0.411 | 0.072 | 0.313 | 0.151 | 0.054 |
Metastases | ||||||
Yes | 52.45(19.93) | 55.29(24.69) | 26.47(38.66) | 42.64(37.71) | 55.88(36.29) | 57.29(37.00) |
No | 64.56(21.25) | 76.22(20.76) | 71.81(33.79) | 64.89(32.77) | 74.61(29.03) | 78.84(29.41) |
P value | 0.016 | 0.001 | 0.000 | 0.016 | 0.024 | 0.009 |
Mastectomy | ||||||
Yes | 60.47(22.93) | 71.86(22.81)777.57(20.22) | 64.22(37.31) | 61.49(34.97) | 74.64(28.91) | 73.50(30.57) |
No | 66.87(19.22) | 72.74(34.43) | 65.02(32.18) | 71.89(30.94) | 81.21(29.84) | |
P-value | 0.026 | 0.053 | 0.053 | 0.536 | 0.613 | 0.010 |
Lumpectomy | ||||||
Yes | 67.08(19.26) | 77.68(20.36) | 72.86(34.16) | 65.48(31.92) | 71.90(30.58) | 81.40(29.59) |
No | 60.14(22.88) | 71.59(22.70) | 63.86(37.59) | 60.91(35.23) | 74.70(29.26) | 73.09(30.76) |
P-value | 0.017 | 0.033 | 0.048 | 0.435 | 0.514 | 0.007 |
Lymph node dissection | ||||||
Yes | 63.44(21.19) | 75.50(21.28) | 67.92(36.40) | 62.64(33.70) | 73.11(29.94) | 77.47(30.50) |
No | 65.00(22.75) | 70.47(24.10) | 70.95(34.61) | 65.71(33.07) | 73.33(30.30) | 77.14(30.54) |
P-value | 0.771 | 0.255 | 0.753 | 0.545 | 0.937 | 0.776 |
Chemotherapy | ||||||
Yes | 64.41(20.95) | 76.00(20.73) | 67.28(37.02) | 61.31(34.19) | 73.54(29.26) | 77.16(30.70) |
No | 60.68(22.88) | 69.42(24.88) | 73.55(31.73) | 71.19(30.00) | 72.10(32.78) | 78.26(29.36) |
P-value | 0.358 | 0.122 | 0.472 | 0.080 | 0.828 | 0.895 |
Radiotherapy | ||||||
Yes | 64.25(21.06) | 75.82(21.94) | 69.72(36.11 | 63.77(33.12) | 73.40(29.60) | 79.10(29.48) |
No | 60.74(22.83) | 68.94(19.68) | 62.28(35.65) | 60.58(36.25) | 72.52(31.96) | 68.42(33.73) |
P-value | 0.538 | 0.024 | 0.172 | 0.779 | 0.992 | 0.043 |
Symptom scales in QLQ-C30
Functional and symptom scales in QLQ-BR 23
Functional scales in BR 23b
| Symptom scale in BR 23c
| |||||||
---|---|---|---|---|---|---|---|---|
Characteristic | Body Image | Sexual functioning | Sexual enjoyment | Future perspective | Systemic therapy side effect | Breast symptoms | Arm symptoms | Upset by hair loss |
Age | ||||||||
≤50 year | 72.53(31.24) | 29.25(29.88) | 48.91(34.02) | 55.55(39.69) | 20.07(18.66) | 16.35(19.75) | 39.09(31.74) | 51.41(43.47) |
>50 years | 79.88(27.45) | 21.38(29.16) | 47.86(28.40) | 68.97(37.78) | 18.19(16.52) | 10.06(14.87) | 33.22(31.64) | 39.02(41.43) |
P-value | 0.134 | 0.744 | 0.103 | 0.257 | 0.453 | 0.034 | 0.983 | 0.257 |
Time since diagnosis | ||||||||
Early diagnosed | 65.47(37.33) | 18.09(27.52) | 55.55(35.76) | 44.76(44.23) | 25.85(19.77) | 20.95(22.17) | 43.80(32.44) | 70.83(34.15) |
Transitional period | 75.67(30.32) | 23.65(27.71) | 44.44(27.89) | 63.22(39.06) | 17.83(17.28) | 11.11(14.45) | 32.18(29.57) | 41.49(42.23) |
Long term survivors | 80.33(23.83) | 33.33(32.76) | 52.27(36.22) | 65.77(35.92) | 18.59(17.10) | 14.55(20.50) | 40.59(34.19) | 41.90(44.53) |
P-value | 0.292 | 0.027 | 0.338 | 0.037 | 0.065 | 0.044 | 0.093 | 0.035 |
Marital status | ||||||||
Single | 74.63(34.31) | 5.07(16.99) | 66.66(−) | 60.86(44.55) | 25.05(25.32) | 13.40(24.71) | 35.26(29.89) | 33.33(40.20) |
Married | 73.88(29.97) | 37.47(29.33) | 48.83(32.03) | 61.63(38.46) | 16.96(14.81) | 14.30(17.74) | 38.22(31.81) | 43.28(43.03) |
Divorced | 80.95(27.62) | 4.76(12.10) | 0.00(−) | 52.38(46.61) | 30.95(20.09) | 18.45(16.72) | 35.71(31.17) | 86.66(32.20) |
Widowed | 81.25(27.59) | 0.00 (0.00) | - | 63.33(38.34) | 20.95(20.51) | 9.58(15.04) | 31.11(33.30) | 43.33(38.65) |
P-value | 0.446 | 0.000 | 0.288 | 0.877 | 0.060 | 0.046 | 0.484 | 0.020 |
Educational level | ||||||||
Illiterate | 82.32(27.79) | 24.71(31.87) | 52.56(30.07) | 75.00(33.96) | 16.06(14.95) | 9.72(15.65) | 32.03(31.36) | 28.07(40.46) |
Primary | 78.88(25.49) | 11.11(22.46) | 33.33(30.86) | 57.77(40.05) | 21.11(17.58) | 13.61(20.81) | 43.70(34.39) | 71.42(40.49) |
Intermediate | 71.01(33.32) | 28.98(32.26) | 52.77(30.01) | 63.76(44.84) | 17.59(20.47) | 16.30(16.94) | 35.26(34.26) | 75.00(38.83) |
High school/diploma | 75.30(30.46) | 26.95(27.20) | 44.20(34.46) | 55.14(39.84) | 20.92(18.87) | 15.12(18.49) | 36.35(30.73) | 40.47(41.99) |
College | 67.26(31.20) | 34.52(31.96) | 55.55(30.56) | 54.76(38.83) | 20.18(17.90) | 15.07(18.88) | 39.15(31.44) | 55.07(42.17) |
P -value | 0.029 | 0.015 | 0.417 | 0.026 | 0.432 | 0.490 | 0.067 | 0.021 |
Employment | ||||||||
Yes | 76.19(28.31) | 29.25(30.90) | 53.33(34.69) | 50.66(38.82) | 20.47(19.76) | 16.66(20.68) | 38.00(30.12) | 51.38(40.50) |
No | 75.57(30.84) | 24.94(29.14) | 47.29(31.69) | 63.69(38.93) | 18.42(17.08) | 13.47(18.10) | 35.31(32.35) | 42.30(43.34) |
Retired | 75.20(28.77) | 25.41(31.12) | 47.05(31.31) | 65.83(40.28) | 20.83(17.80) | 10.62(13.73) | 39.44(32.11) | 50.72(45.91) |
P-value | 0.885 | 0.697 | 0.756 | 0.070 | 0.683 | 0.425 | 0.610 | 0.558 |
Monthly income | ||||||||
<500 | 75.38(30.40) | 17.30(25.95) | 42.85(30.42) | 60.60(40.52) | 21.51(17.70) | 13.63(18.34) | 35.35(30.44) | 47.27(42.88) |
500–999 | 75.00(29.37) | 35.38(31.82) | 50.00(35.30) | 61.40(40.72) | 17.62(20.91) | 14.91(17.23) | 37.42(33.89) | 43.05(43.38) |
>1000 | 78.62(27.97) | 78.62(30.19) | 55.95(30.16) | 63.76(35.01) | 15.21(12.32) | 10.86(16.18) | 37.68 (32.32) | 48.33(45.20) |
P-value | 0.780 | 0.000 | 0.231 | 0.965 | 0.035 | 0.354 | 0.901 | 0.906 |
Menopausal status | ||||||||
Premenopause | 71.43(31.97) | 30.00(29.93) | 48.48(34.68) | 56.36(39.29) | 19.56(17.73) | 17.27(20.05) | 40.30(31.92) | 48.97(43.08) |
Perimenopause | 77.31(28.28) | 26.85(29.08) | 49.01(26.66) | 56.48(41.26) | 20.50(20.22) | 15.74(19.08) | 34.87(32.00) | 54.76(46.42) |
Postmenopause | 80.20(27.22) | 20.45(29.33) | 48.48(30.15) | 69.25 (37.80) | 18.408(16.88) | 8.42(13.42) | 32.71(31.31) | 39.81(42.02) |
P-value | 0.091 | 0.049 | 0.985 | 0.047 | 0.876 | 0.001 | 0.169 | 0.473 |
Pathological staging | ||||||||
Stage 0 and I | 76.28(28.26) | 22.64(26.34) | 43.75(33.81) | 60.68(41.09) | 19.65(13.69) | 17.09(18.72) | 42.16(32.16) | 56.25(48.25) |
Stage II | 78.67(29.57) | 25.42(28.42) | 47.31(33.08) | 61.58(40.02) | 20.33(19.24) | 14.40(20.63) | 36.34(31.21) | 33.33(36.00) |
Stage III and IV | 61.51(36.17) | 20.09(25.87) | 48.88(27.79) | 52.94(45.03) | 24.36(21.51) | 15.93(19.82) | 36.92(34.46) | 50.00(40.82) |
P-value | 0.052 | 0.761 | 0.884 | 0.609 | 0.691 | 0.560 | 0.363 | 0.225 |
Metastases | ||||||||
Yes | 71.56(35.36) | 14.70(24.21) | 33.33(36.51) | 47.05(39.19) | 36.13(29.26) | 28.43(25.52) | 54.24(35.54) | 43.33(44.58) |
No | 75.96(29.46) | 26.80(30.03) | 49.39(31.84) | 62.40(39.26) | 17.95(15.91) | 12.51(16.90) | 35.21(31.12) | 46.81(43.14) |
P-value | 0.585 | 0.117 | 0.299 | 0.131 | 0.013 | 0.008 | 0.033 | 0.831 |
Mastectomy | ||||||||
Yes | 70.01(33.22) | 26.35(29.13) | 47.77(32.10) | 62.14(40.63) | 19.69(19.06) | 14.33(19.21) | 37.75(31.66) | 46.80(43.21) |
No | 81.26(24.97) | 25.49(30.52) | 49.40(32.40) | 60.45(38.22) | 18.84(16.41) | 12.99(16.89) | 35.40(31.95) | 46.15(43.36) |
P-value | 0.022 | 0.665 | 0.768 | 0.684 | 0.964 | 0.827 | 0.499 | 0.965 |
Lumpectomy | ||||||||
Yes | 80.76(24.91) | 24.58(30.47) | 48.80(33.61) | 60.60(38.49) | 18.80(16.26) | 13.42(17.98) | 35.44(31.76) | 45.28(43.40) |
No | 70.24(33.58) | 27.33(29.09) | 48.33(30.94) | 60.02(40.43) | 19.75(19.26) | 13.98(18.22) | 37.77(31.86) | 47.82(43.12) |
P-value | 0.059 | 0.322 | 0.933 | 0.736 | 0.931 | 0.846 | 0.529 | 0.788 |
Lymph node dissection | ||||||||
Yes | 74.53(30.39) | 25.75(29.59) | 47.81(33.38) | 59.50(39.52) | 19.59(17.60) | 13.12(17.15) | 37.22(31.87) | 48.23(43.18) |
No | 81.42(26.66) | 25.71(30.87) | 52.08(24.24) | 70.47(37.72) | 17.50(19.07) | 15.71(22.11) | 32.06(31.28) | 38.46(42.70) |
P-value | 0.249 | 0.884 | 0.754 | 0.115 | 0.406 | 0.728 | 0.348 | 0.434 |
Chemotherapy | ||||||||
Yes | 73.89(30.73) | 27.03(29.70) | 48.14(33.40) | 60.17(39.97) | 20.10(18.26) | 14.29(18.49) | 37.95(31.22) | 46.89(42.58) |
No | 82.78(25.05) | 21.37(29.95) | 50.98(23.91) | 65.94(36.84) | 15.76(15.15) | 11.05(16.10) | 30.91(33.69) | 43.58(47.88) |
P-value | 0.071 | 0.161 | 0.781 | 0.387 | 0.144 | 0.213 | 0.097 | 0.806 |
Radiotherapy | ||||||||
Yes | 76.56(29.28) | 26.14(30.12) | 50.34(31.83) | 61.11(39.27) | 18.37(16.86) | 13.25(17.79) | 36.64(31.58) | 43.20(42.30) |
No | 70.72(32.78) | 24.77(28.22) | 38.88(32.83) | 62.28(40.39) | 24.06(21.58) | 15.78(19.54) | 36.25(33.15) | 61.11(44.64) |
P-value | 0.335 | 0.970 | 0.193 | 0.837 | 0.220 | 0.389 | 0.869 | 0.117 |
Predictors of quality of life
Global QoL score | Physical functioning | Role functioning | Emotional functioning | Cognitive functioning | Social functioning | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance | Standardized Coefficients Beta | Significance |
Constant | 63.298 | <0.001 | 36.082 | 0.024 | 56 | 0.032 | 77.93 | 0.001 | 71.909 | 0.001 | 41.898 | 0.047 |
Age > 50
| −0.007 | 0.956 | 0.187 | 0.103 | 0.022 | 0.848 | 2.757 | 0.007 | 0.135 | 0.285 | 0 | 0.999 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Married
| 0.116 | 0.231 | 0.129 | 0.168 | 0.076 | 0.434 | 0.837 | 0.404 | 0.11 | 0.288 | 0.35 | <0.001 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Education
| −0.024 | 0.844 | 0.192 | 0.103 | −0.021 | 0.861 | −0.25 | 0.803 | −0.112 | 0.384 | −0.137 | 0.244 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Employment
| −0.018 | 0.853 | −0.109 | 0.252 | −0.078 | 0.429 | −0.863 | 0.39 | 0.036 | 0.732 | −0.054 | 0.571 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
High Income
| 0.109 | 0.29 | 0.086 | 0.391 | 0.171 | 0.098 | 1.612 | 0.11 | 0.101 | 0.361 | 0.25 | 0.014 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Menopause
| −0.259 | 0.031 | −0.128 | 0.269 | 0.068 | 0.565 | −0.621 | 0.536 | −0.01 | 0.934 | 0.034 | 0.769 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Advanced stage
| −0.275 | 0.005 | −0.061 | 0.516 | −0.189 | 0.051 | −0.54 | 0.59 | −0.106 | 0.304 | −0.156 | 0.101 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Late survivors
| −0.105 | 0.263 | −0.021 | 0.819 | 0.071 | 0.447 | 0.861 | 0.391 | −0.067 | 0.506 | −0.015 | 0.873 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Comorbidities
| −0.027 | 0.783 | −0.046 | 0.63 | 0.054 | 0.58 | −2.171 | 0.032 | 0.037 | 0.725 | −0.088 | 0.363 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Metastases
| −0.086 | 0.385 | −0.297 | 0.002 | −0.303 | 0.003 | −1.691 | 0.094 | −0.174 | 0.1 | −0.103 | 0.285 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Lumpectomy
| 0.321 | 0.205 | 0.45 | 0.068 | 0.15 | 0.551 | 0.746 | 0.457 | 0.072 | 0.789 | 0.265 | 0.282 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Mastectomy
| 0.319 | 0.203 | 0.417 | 0.087 | 0.109 | 0.659 | 0.938 | 0.35 | 0.128 | 0.632 | 0.166 | 0.495 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Lymph node dissection
| −0.068 | 0.461 | 0.052 | 0.559 | −0.01 | 0.917 | −1.763 | 0.081 | −0.013 | 0.892 | 0.031 | 0.731 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Chemotherapy
| −0.033 | 0.743 | −0.07 | 0.466 | −0.061 | 0.535 | −2.646 | 0.009 | −0.095 | 0.371 | −0.043 | 0.654 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Radiotherapy
| −0.085 | 0.376 | 0.159 | 0.089 | 0.061 | 0.524 | 0.139 | 0.89 | −0.046 | 0.65 | 0.083 | 0.377 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
Hormonal therapy
| 0.036 | 0.688 | −0.063 | 0.464 | −0.178 | 0.047 | −0.76 | 0.449 | 0.04 | 0.677 | 0.008 | 0.931 |
No = 0 | ||||||||||||
Yes = 1 | ||||||||||||
R squared
| 0.24 | 0.28 | 0.25 | 0.25 | 0.132 | 0.281 | ||||||
P-value
| 0.015 | 0.002 | 0.009 | 0.01 | 0.455 | 0.002 |