Background
Methods
Study population
Imaging
Image assessment
Treatment
Statistical analysis
Results
PT regression speed after RT and survival
Prognostic value of PT regression speed at the end of RT
Endpoint | Variable | Estimate | HR†
| 95% CI* |
P value‡
|
---|---|---|---|---|---|
OS | Regression speed | 0.778 | 2.177 | 1.480-3.203 | < 0.001 |
FFS | Regression speed | 0.764 | 2.148 | 1.384-3.333 | 0.001 |
DMFS | Regression speed | 0.812 | 2.252 | 1.296-3.912 | 0.004 |
LRFS | Regression speed | 0.681 | 1.975 | 0.976-3.995 | 0.058 |
Prognosis comparison of patients with CRPT during RT and patients with CRPT only at the end of RT
Variable | CRPT during RT (N = 41) | CRPT at the end of RT (N = 35) | HR †(95% CI*) |
P
‡
|
---|---|---|---|---|
5-yr OS rate | 79.9% | 88.6% | 0.590 (0.177-1.962) | 0.383 |
5-yr FFS rate | 80.2% | 97.1% | 0.144 (0.018-1.151) | 0.033 |
5-yr DMFS rate | 87.1% | 97.1% | 0.233 (0.027-1.992) | 0.146 |
5-yr LRFS rate | 92.4% | 100% | 0.018 (0.000-206.004) | 0.113 |
Value of boost irradiation in patients with persistent PT at the end of RT
Variable | Without boost irradiation (N = 27) | With boost irradiation (N = 85) | HR †(95% CI*) |
P
‡
|
---|---|---|---|---|
5-yr OS rate | 65.5% | 63.9% | 1.308 (0.622-2.748) | 0.477 |
5-yr FFS rate | 73.1% | 67.7% | 1.267 (0.547-2.934) | 0.579 |
5-yr DMFS rate | 84.4% | 79.2% | 1.350 (0.451-4.039) | 0.589 |
5-yr LRFS rate | 87.1% | 84.6% | 1.170 (0.322-4.252) | 0.812 |