Background
Materials and methods
Patients and protocol
Variable | Patients without LVDD n = 78 Mean | Patients with LVDD n = 75 Mean | p value |
---|---|---|---|
Age | 50 ± 12 | 59 ± 10 | < 0.001 |
Sex (% male) | 51 | 49 | 0,1 |
SBP (mmHg) | 134 ± 16 | 141 ± 16 | 0.006 |
DBP (mmHg) | 79 ± 9.0 | 80 ± 8.0 | 0.6 |
HT (%) | 36 | 58 | 0.009 |
Crea ((μmol/L) | 73 ± 19 | 81 ± 42 | 0.1 |
GFR (ml/min) | 137 ± 52 | 116 ± 41 | 0.005 |
Dyslipidemia (%) | 51 | 49 | 0,3 |
lnAER ( g/min) | 2.1 ± 1.3 | 2.3 ± 1.7 | 0.4 |
lnBNP (pmol/L) | 1.1 ± 1.0 | 1.6 ± 1.1 | 0.01 |
HbA1c (%) | 7.0 ± 2.0 | 6.5 ± 1.4 | 0.04 |
fP-glucose (mmol/L) | 9.3 ± 3.8 | 8.9 ± 3.0 | 0.5 |
DM duration (years) | 4,7 ± 6,6 | 8.0 ± 7.6 | 0.005 |
Smoking (%) | 15 | 9 | 0.2 |
BMI (kg/m2) | 30 ± 6.1 | 31 ± 5.2 | 0.3 |
TG (mmol/L) | 1.8 ± 1.1 | 1.8 ± 1.0 | 1.0 |
HDL (mmol/L) | 1.1 ± 0.3 | 1.2 ± 0.4 | 0.3 |
LDL (mmol/L) | 2.9 ± 0.8 | 2.7 ± 1.0 | 0.2 |
BSA (m2) | 2.0 ± 0.24 | 2.0 ± 0.20 | 0.5 |
Variable | Patients without LVDD n = 78 Mean | Patients with LVDD n = 75 Mean | p value |
---|---|---|---|
EF (%) | 60 ± 6.2 | 56 ± 10 | 0.03 |
E (cm/s) | 78 ± 15 | 79 ± 18 | 0.8 |
A (cm/s) | 68 ± 15 | 97 ± 57 | 0.001 |
Edt (s) | 0.2 ± 0.06 | 0.2 ± 0.05 | 0.2 |
Pulmonary vein flow | 1.4 ± 0.7 | 1.2 ± 0.6 | 0.2 |
RA diameter (mm/m2) | 24 ± 4,5 | 25 ± 4.4 | 0.3 |
IVSDd (mm/m2) | 5.8 ± 1.0 | 6.0 ± 0.8 | 0.3 |
LVIDd (mm/m2) | 24 ± 2.5 | 24 ± 2.6 | 0.5 |
RVIDd (mm/m2) | 14 ± 1.9 | 15 ± 2.2 | 0.2 |
PWDd (mm/m2) | 4.6 ± 0.7 | 4.5 ± 0.7 | 0.6 |
PSVsept (cm/s) | 9.2 ± 6.8 | 7.7 ± 1.6 | 0.1 |
Èsept (cm/s) | 10 ± 6.7 | 6.7 ± 1.8 | 0.001 |
Ásept (cm/s) | 9.3 ± 2.0 | 10 ± 2.6 | 0.06 |
PSVlat (cm/s) | 8.9 ± 2.4 | 8.4 ± 2.0 | 0.2 |
Élat (cm/s) | 11 ± 3.2 | 9.1 ± 2.3 | < 0.001 |
Álat (cm/s) | 10 ± 3.6 | 11 ± 3.1 | 0.2 |
LA diameter (mm/m2) | 20 ± 2.3 | 20 ± 1.9 | 0.7 |
LVM (g/m2) | 87 ± 22 | 88 ± 25 | 0.9 |