Background
Methods
Study design
Targeted IRS
Sample size of the epidemiological survey
Intervention | Nonintervention | Buffer areas† | |||
---|---|---|---|---|---|
Valley
|
Uphill
|
Valley
|
Uphill
| ||
Approximate population | 2800 | 8800 | 2200 | 7400 | 10800 |
Mosquito survey: Mean number of houses sampled per survey | 24 | 79 | 29 | 65 | 103 |
Monthly parasite survey: Mean number of children sampled per survey | 45 | 75 | 48 | 134 | 84 |
Cohort study: Mean number of children sampled per survey | 113 | 154 | 112 | 249 | 321 |
Cohort study
Entomological survey
Statistical analysis
Results
Baseline parasitological descriptive statistics
Temporal dynamics of Plasmodium prevalence
Location | Survey period | Intervention | Nonintervention | Adjusted reduction (%)† |
---|---|---|---|---|
P. falciparum prevalence (%) | ||||
Valley | Before intervention | 63.61 [53.63, 73.61] | 39.71 [32.24, 47.18] | |
Valley | After intervention | 16.44 [7.81, 25.11] | 29.62 [23.16, 36.09] | 65.35 |
Uphill | Before intervention | 44.86 [34.87, 54.85] | 25.04 [17.57, 32.51] | |
Uphill | After intervention | 18.53 [9.88, 27.18] | 19.28 [12.81, 25.74] | 46.35 |
An. gambiae density (female/house/night) | ||||
Valley | Before intervention | 3.41 [1.04, 5.76] | 2.06 [0, 5.14] | |
Valley | After intervention | 0.17 [0, 2.28] | 3.18 [0.42, 5.93] | 96.82 |
Uphill | Before intervention | 0.94 [0, 3.31] | 0.61 [0, 4.11] | |
Uphill | After intervention | 0.47 [0, 2.58] | 0.63 [0, 3.05] | 51.6 |
An. funestus density (female/house/night) | ||||
Valley | Before intervention | 0.78 [0.25, 1.31] | 0.23 [0.06, 0.39] | |
Valley | After intervention | 0.06 [0, 0.54] | 0.12 [0, 0.27] | 85.26 |
Uphill | Before intervention | 0.26 [0, 0.79] | 0.08 [0, 0.25] | |
Uphill | After intervention | 0.05 [0, 0.53] | 0.05 [0, 0.19] | 69.23 |