Background
Link between pulmonary capillary hypertension and the clinical syndrome of congestive HF: insights from hemodynamic evidence
Reliability of spectral tissue Doppler echocardiography as a noninvasive surrogate for LV diastolic pressures
Reference | Population study | Number of patients | r-value | LV ejection fraction |
---|---|---|---|---|
Sundereswan (1998)48
| Heart transplants | 50 | 0.8 (L) | 56 ± 12% |
Nagueh (1998)49
| ICU/Catheterism | 49 | 0.72 (L) | > 45% |
Nagueh (1999)50
| HCM | 35 | 0.76 (L) | > 50% |
Sohn (1999)51
| Atrial fibrillation | 27 | 0.79 (S) | 53 ± 11% |
Ommen (2000)45
| Catheterism | 64 | 0.47 (S) | > 50% |
Kim (2000)52
| Catheterism | 167 | 0.74 (S) | > 50% |
Gonzalez (2002)53
| ICU | 32 | 0.54 (L) | > 50% |
Rivas-Gotz (2003)54
| ICU/Catheterism | 55 | 0.7 (L) | > 50% |
Bruch (2004)57
| Aortic stenosis | 23 | 0.75 (S) | 59 ± 11% |
Bruch (2005)58
| Diastolic HF | 28 | 0.56 (A) | > 45% |
Hadano (2005)59
| Catheterism | 65 | 0.54 (L) | > 50% |
Paelinck (2005)60
| Chronic hypertension | 18 | 0.85 (S) | 58 ± 7% |
Usefulness of spectral tissue Doppler echocardiography in predicting HFPSF in the setting of exercise intolerance
Reference | Population study | Number of patients | Relation with PVo2 | Spectral tissue Doppler index measured at rest |
---|---|---|---|---|
Matsumura79
| HCM | 85 | -0.42* (p < 0.001) | Lateral E/E' ratio |
McMahon80
| HCM in children | 80 | -0.74* (p < 0.001) | Septal E/E' ratio |
Ha81
| HCM | 29 | -0.47* (p = 0.01) | Septal E/E' ratio |
Smart82
| Chronic systolic HF | 95 | -0.31* (p = 0.001) | Average E/E' ratio |
Lee83
| Permanent atrial fibrillation | 73 | -0.35† (p = 0.03) | Septal E/E' ratio |
Hadano84
| Chronic LV systolic dysfunction | 53 | -0.68* (p < 0.001) | Lateral E/E' ratio |
Van de Veire85
| CAD and preserved LV systolic function | 142 | p = 0.005‡
| Septal E/E' ratio |
Reference
|
Population study
|
Number of patients
|
Relation with METs
|
Spectral tissue Doppler index measured at rest
|
Skaluba86
| Clinically indicated treadmill exercise | 121 | -0.68* (p < 0.001) | Septal E/E' ratio |
Burgess78
| Clinically indicated treadmill exercise | 166 | -0.37* (p < 0.001) | Septal E/E' ratio |
Reference
|
Population study
|
Number of patients
|
Relation with METs
|
Post-exercise spectral tissue Doppler index
|
Burgess78
| Clinically indicated treadmill exercise | 166 | -0.44* (p < 0.001) | Septal E/E' ratio |
2-dimensional and M-mode echocardiography* |
-Mildly decreased left ventricular ejection fraction (45–54%) at 2D methods |
-Abnormal left ventricular remodeling |
-Left ventricular segmental wall motion abnormalities |
-Increased left atrial size |
Doppler echocardiography
|
-Doppler indexes suggestive of abnormal left ventricular relaxation: mitral inflow E/A ratio < 0.75; spectral tissue Doppler-derived lateral Ea velocity < 8 cm/s; color M-mode-derived Vp velocity < 45 cm/s |
-Index of myocardial performance > 0.60 |
-Increased pulmonary artery pressure |
Usefulness of bedside spectral tissue Doppler echocardiography in the emergency diagnosis of acute HFPSF
Reference | Population study | Number of patients | Sensitivity-Specificity | Threshold value for E/E' |
---|---|---|---|---|
Dokainish97
| NYHA II to IV LVEF < 50% | 76 | 92% – 72% | Average E/E' > 15 |
Dokainish97
| NYHA II to IV LVEF > 50% | 46 | 79% – 93% | Average E/E' > 15 |
Arques98
| Acute dyspnea at rest LVEF > 45% | 70 | 80% – 94.3% 76.7% – 91.4% | Average E/E' > 11.5 Septal E/E' > 13 |
Arques99
| Acute dyspnea at rest LVEF > 50%, BNP 100–400 pg/ml | 34 | 88.2% – 76.5% 76.5% – 88.2% | Average E/E' > 10.1 Septal E/E' > 13 |
Arques100
| Acute dyspnea at rest, elderly LVEF > 50%, atrial fibrillation | 41 | 81.8% – 89.5% | Septal E/E' > 13 |
Arques104
| Acute dyspnea LVEF > 50%, hypertension | 40 | 77.8% – 100% | Lateral E/E' > 11 |
Huang105
| Acute dyspnea LVEF < 50% | -* | 70.8% – 100% | Average E/E' > 16 |
Huang105
| Acute dyspnea LVEF > 50% | -* | 88.9% – 82.9% | Average E/E' > 11 |