Introduction
Patients and methods
Statistical analysis
Results
Patient characteristics |
Total
|
---|---|
Number of Patients | 96 |
Male/Female ratio | 42/54 |
Age (mean/Standard deviation) | 48.8 (±1.49) |
Education | |
Not a high school graduate | 12 (12.5%) |
High school graduate | 44 (46.8%) |
College graduate | 38 (40.4%) |
Marital Status | |
Married | 76 (79.9) |
Divorced | 4 (4.2) |
Widowed | 6 (4.3) |
Single | 10 (10.4) |
Occupational Status | |
Full-time Job | 54 (56.3) |
Part-time Job | 10 (10.4) |
Retired | 6 (6.3) |
Unemployed | 26 (27) |
Subscalestotal (n = 96) |
Mean scores (± SE)
|
---|---|
EORTC QLQ-C30
| |
Functional Scales
| |
Physical Function | 70.9 (± 2.2) |
Role Function | 68.4 (± 2.6) |
Emotional Function | 56.9 (± 2.7) |
Cognitive Function | 68.7 (±2.6) |
Social Function | 64.2 (± 3.3) |
Symptom Scales
| |
Fatigue | 45.1 (±2.6) |
Pain | 33 (± 3.0) |
Nausea & Vomiting | 10.06 (± 1.9) |
Single Items
| |
Dyspnea | 10.4 (± 2.2) |
Insomnia | 33.3 (± 3.4) |
Appetite Loss | 19.4 (± 2.5) |
Constipation | 15.9 (±2.4) |
Diarrhea | 18.7 (± 2.6) |
EORTC QLQ-CR38
| |
Functional Scales
| |
Body Image | 63.2 (± 3.1) |
Future perspective | 50.3 (± 4.02) |
Sexual functioning | 56.5 (± 3.9) |
Sexual Enjoyment | 24.1 (± 3.0) |
Symptom Scales
| |
Radiation-Induced effects on micturition | 26.9 (±2.5) |
Chemotherapy side effects | 19.4 (±2.1) |
General Gastrointestinal Symptoms | 35.1 (±2.5) |
Stoma -related Problems | 52.3 (± 2.7) |
Sexual Dysfunction of Men | 20±5.07 |
Sexual Dysfunction of Women | 25±4.2 |
Weight Loss | 23.7 (±3.1) |
Gender differences and QoL
EORTC QLQ-C30 | Male | Female | P Value |
---|---|---|---|
Functional Scales
| |||
Physical Function | 76.5±3.3 | 66.6±2.8 | 0.02* |
Role Function | 72.2±3.6 | 65.4±3.7 | 0.2 |
Emotional Function | 60.7±4.0 | 54.0±3.7 | 0.2 |
Cognitive Function | 73.0±4.0 | 65.4±3.4 | 0.1 |
Social Function | 66.6±4.3 | 62.3±4.8 | 0.5 |
Symptom Scales
| |||
Fatigue | 41.7±3.7 | 47.7±3.6 | 0.2 |
Pain | 32.5±4.7 | 33.9±3.8 | 0.8 |
Nausea & Vomiting | 11.9±3.5 | 8.6±2.0 | 0.3 |
Single Items
| |||
Dyspnea | 11.1±3.3 | 9.8±3.0 | 0.7 |
Insomnia | 30.1±4.7 | 35.8±4.8 | 0.4 |
Appetite Loss | 22.2±4.0 | 17.2±3.1 | 0.3 |
Constipation | 19.0±4.4 | 13.5±2.5 | 0.2 |
Diarrhea | 17.4±3.8 | 19.7±3.5 | 0.6 |
EORTC QLQ-CR38 | Male | Female | P Value |
---|---|---|---|
Functional Scales
| |||
Body Image | 75.1±3.4 | 52.7±4.7 | 0.00* |
Future perspective | 57.1±5.3 | 44.8±5.7 | 0.1 |
Sexual functioning | 72.5±6.0 | 42.7±4.3 | 0.00* |
Sexual Enjoyment | 40.3±4.5 | 9.5±2.3 | 0.00* |
Symptom Scales
| |||
Radiation-Induced effects on micturition | 33.3±3.7 | 21.2±3.2 | 0.01* |
Chemotherapy side effects | 13.2±2.1 | 25.1±3.4 | 0.005* |
General Gastrointestinal Symptoms | 29.5±3.0 | 40.2±3.8 | 0.03* |
Stoma-related Problems | 41.8±2.8 | 60.4±4.0 | 0.00* |
Sexual Dysfunction of Men | 20±5.07 | - | - |
Sexual Dysfunction of Women | - | 25±4.2 | - |
Weight Loss | 30.1±5.5 | 18.0±3.1 | 0.06 |
Age difference in sexuality and QoL
Subscales
| Females | Males | ||||
---|---|---|---|---|---|---|
< 44.5 years old (n = 26)
|
≥44.5 years old (n = 26)
|
P Value
|
< 53 years old (n = 22)
|
≥53 years old (n = 20)
|
P Value
| |
EORTC QLQ-C30
| ||||||
Functional Scales
| ||||||
Physical Function | 64.6±4.5 | 68.7±3.9 | 0.4 | 78.1±4.7 | 74.6±4.7 | 0.6 |
Role Function | 58.9±5.7 | 76.9±2.7 | 0.00* | 69.6±4.6 | 75±5.7 | 0.4 |
Emotional Function | 44.8±5.2 | 62.1±5.4 | 0.02* | 70.4±4.5 | 50.0±6.2 | 0.01* |
Cognitive Function | 61.5±5.4 | 66.6±4.1 | 0.4 | 75.7±6.2 | 70.0±5.0 | 0.4 |
Social Function | 58.9±7.1 | 67.9±7.0 | 0.3 | 60.6±6.4 | 73.3±5.4 | 0.1 |
Symptom Scales
| ||||||
Fatigue | 54.7±4.4 | 40.1±5.8 | 0.05 | 37.3±4.5 | 46.6±6.1 | 0.2 |
Pain | 35.8±4.3 | 32.0±6.8 | 0.6 | 33.3±5.8 | 0.8 | |
Nausea & Vomiting | 8.9±2.8 | 7.6±3.0 | 0.7 | 10.6±2.8 | 13.3±6.7 | 0.7 |
Single Items
| ||||||
Dyspnea | 5.1±2.4 | 15.3±5.6 | 0.1 | 9.0±4.4 | 13.3±5.0 | 0.5 |
Insomnia | 38.4±6.3 | 35.8±7.6 | 0.7 | 21.2±4.6 | 40.0±8.2 | 0.05 |
Appetite Loss | 25.6±4.6 | 10.2±4.0 | 0.01* | 21.2±4.6 | 23.3±6.8 | 0.8 |
Constipation | 12.8±4.1 | 12.8±3.2 | 0.9 | 27.2±6.8 | 10.0±4.8 | 0.05 |
Diarrhea | 20.5±6.1 | 17.9±4.2 | 0.7 | 15.1±3.6 | 20.0± | 0.5 |
EORTC QLQ-CR38
| ||||||
Functional Scales
| ||||||
Body Image | 45.2±6.5 | 61.6±30.0 | 0.08 | 80.8±3.2 | 68.8±6.1 | 0.09 |
Future perspective | 33.3±7.3 | 56.4±8.4 | 0.04* | 57.5±6.2 | 56.6±9.0 | 0.9 |
Sexual functioning | 46.6±5.8 | 39.7±6.3 | 0.4 | 81.8±6.8 | 61.1±10.0 | 0.08 |
Sexual Enjoyment | 16.6±3.8 | 3.0±2.0 | 0.00* | 51.5±5.6 | 25.0±5.6 | 0.00* |
Symptom Scales
| ||||||
Radiation-Induced effects on micturition | 23.2±5.6 | 19.6±3.6 | 0.5 | 32.2±5.7 | 34.4±4.8 | 0.7 |
Chemotherapy side-effects | 27.2±5.4 | 23.1±4.3 | 0.5 | 14.1±3.1 | 12.2±3.1 | 0.6 |
General Gastrointestinal Symptoms | 50.3±5.5 | 31.1±4.6 | 0.01* | 29.6±4.3 | 29.3±4.2 | 0.9 |
Stoma -related Problems | 78.0±3.8 | 47.6±5.2 | 0.00* | 41.9±3.8 | 41.6±4.2 | 0.9 |
Sexual Dysfunction | 37.5±9.0 | 16.6±3.1 | 0.04* | 28.5±9.7 | 12.5±3.5 | 0.1 |
Weight Loss | 15.1±4.7 | 20.5±4.1 | 0.4 | 33.3±8.2 | 26.6±7.4 | 0.5 |