Background
Patients and methods
Patients
Quality of life and operative risk stratification
Risk | Risk factor |
---|---|
Patient-related | |
Age | |
Female gender | |
Chronic pulmonary disease | |
Extracardiac arteriopathy | |
Neurological dysfunction | |
Previous cardiac surgery | |
Serum creatinine | |
Active endocarditis | |
Critical preoperative state | |
Cardiac-related | |
Unstable angina | |
Left ventricular dysfunction | |
Recent myocardial infarction | |
Pulmonary hypertension | |
Operation-related | |
Emergency | |
Other than isolated coronary artery bypass grafting | |
Surgery on thoracic aorta | |
Postinfarct septal rupture |
Follow-up
Method
Statistical analysis
Study endpoints
Results
<30thpercentile, N | ≥30thN ≤ 70th | > 70thpercentile, N | |
---|---|---|---|
Age (years) | < 62, N:499 | N = 676 | >73, N = 500 |
EQ-5D | <0.72, N = 480 | N = 549 | >0.84, N = 646 |
EQ-VAS | <50, N = 311 | N = 787 | >75, N = 577 |
EuroSCORE risk | < 1.8, N = 500 | N = 681 | >4.6, N = 494 |
Studied correlation | Pearson’s r | p-value |
---|---|---|
Age and postoperative EQ-VAS | −0.082 | 0.003 |
Age and postoperative EQ-5D | −0.030 | 0.277 |
EuroSCORE and postoperative EQ-VAS | −0.137 | 0.001 |
EuroSCORE and postoperative EQ-5D | −0.064 | 0.021 |
Preoperative and postoperative EQ-VAS | 0.285 | 0.001 |
Preoperative and postoperative EQ-5D | 0.368 | 0.001 |
Variable | Drop outs | Complete | p-value |
---|---|---|---|
N = 372 | N = 1303 | ||
Age | 68.7 ± 11.1 (18–86) | 66.1 ± 10.0 (25–93) | 0.001 |
EuroSCORE | 4.1 ± 5.4 (0.88-42.5) | 3.8 ± 3.9 (0.88-51.1) | 0.001 |
EQ-VAS | 59.5 ± 20.7 (0–100) | 64.3 ± 21.1 (0–100) | 0.001 |
EQ-5D | 0.65 ± 0.30 (−0.26-1.00) | 0.74 ± 0.24 (−0.30-1.00) | 0.001 |
Total | Drop out | Complete | p-value | |
---|---|---|---|---|
N = 1675 | N = 372 (%) | N = 1303 (%) | ||
Age (years) | 0.001 | |||
<62 | 499 | 89 (17,8) | 410 (82.2) | |
≥ 62 and ≤73 | 676 | 136 (20.1) | 540 (79.9) | |
>73 | 500 | 147 (29.4) | 353 (70.6) | |
EuroSCORE | 0.001 | |||
< 1.8 | 500 | 63 (12.6) | 437 (87.4) | |
≥ 1.8 and ≤4.6 | 681 | 145 (21.3) | 536 (78.7) | |
>4.6 | 494 | 164 (33.2) | 330 (66.8) | |
EQ-VAS | 0.003 | |||
<50 | 311 | 86 (27.7) | 225 (72.3) | |
≥ 50 and ≤75 | 787 | 182 (23.1) | 605 (76.9) | |
>75 | 577 | 104 (18.0) | 473 (82.0) | |
EQ-5D | 0.001 | |||
<0.72 | 480 | 141 (29.4) | 339 (70.6) | |
≥ 0.72 and ≤0.84 | 549 | 111 (20.2) | 438 (79.8) | |
>0.84 | 646 | 120 (18.6) | 526 (81.4) |