Figure 2
Scatter plots showing the E2 mobility (mean absolute E2 angle change between diastole and systole) for all subjects at the two imaged cardiac phases. A) Global mean E2A values. B) Global controls vs HCM cohort with the myocardium divided into three different regions: regions with hypertrophy and LGE (H+LG+), regions with hypertrophy but no LGE (H+LG-), and regions with no hypertrophy or LGE (H-LG-). In all plots the median and interquartile range are shown. Of note, it shows the most abnormal orientations, inclined steeply inward from the wall plane with low mobility, in the hypertrophic regions, whether not there is LGE evidence of fibrosis. *P-value multiplied by 2 for Bonferroni correction for 2 tests. †P-value multiplied by 3 for Bonferroni correction for 3 tests.