Background
The ANA test in health and disease
ANA in healthy populations
ANA in clinic populations-ANA titers
ANA immunofluorescent staining
Practical Concerns about ANA Testing
Referrals for positive ANA titers
Development of rheumatic diseases in ANA positive individuals
ANA and other diseases
Rheumatic | Non-rheumatic |
---|---|
Juvenile rheumatoid arthritis | Infection-(e.g., viral, Lyme) |
Psoriatic arthritis | Malignancy (e.g., ALL) |
Systemic lupus erythematosus | Environmental toxins |
Systemic lupus erythematosus | Drugs |
Juvenile dermatomyositis | |
Mixed Connective Tissue Disease | |
Drug-induced lupus syndrome |
Diseases with ANA positivity | Diseases without ANA positivity |
---|---|
Systemic lupus erythematosus | Systemic onset JIA |
Juvenile idiopathic arthritis (excluding enthesitis-related arthritis) | Rheumatic fever |
Juvenile dermatomyositis | Post-streptococcal arthritis |
Scleroderma-systemic and local | Enthesitis-related arthritis |
Mixed Connective Tissue Disease | Reactive arthritis syndromes |
Henoch-Schönlein purpura | |
Kawasaki disease | |
Other vasculitis syndromes | |
Sarcoidosis |