Background
Methods
Case definitions
Search strategy
Inclusion criteria | Exclusion criteria |
---|---|
Meets the pre-determined case definitions of major depression and IHD | Cross-sectional study design |
Longitudinal case–control or cohort study design | Clinical samples, for example, studies using hospital data |
Sampling is from the general population | |
Demographic characteristics of sample represent populations at risk | |
Estimate of risk and associated uncertainty/error is reported, or sufficient data is reported to allow calculations of these | |
Where multiple papers draw on the same sample, the most comprehensive or recent publication is preferred | |
Subjects with clinical manifestations of IHD at baseline should be excluded or, at the very least, controlled or stratified for in the analysis |
Meta-analysis
Attributable burden estimation
Results
Systematic search and meta-analysis
Burden of disease
Region | Disability-adjusted life years | Years of life lost | Years lived with a disability |
---|---|---|---|
Asia Pacific, High Income | 39,982 (19,701 to 66,462) | 33,769 (16,218 to 56,464) | 6,212 (2,413 to 12,936) |
Asia, Central | 112,925 (57,161 to 177,173) | 108,331 (54,721 to 170,514) | 4,593 (1,983 to 8,725) |
Asia, East | 386,610 (186,346 to 616,455) | 347,277 (164,890 to 550,414) | 39,332 (17,416 to 70,703) |
Asia, South | 863,351 (429,292 to 1,375,835) | 829,281 (411,750 to 1,325,451) | 34,069 (15,321 to 60,095) |
Asia, Southeast | 263,285 (135,382 to 421,193) | 245,258 (125,893 to 395,411) | 18,026 (7,955 to 32,258) |
Australasia | 9,622 (4,870 to 15,408) | 8,541 (4,344 to 13,721) | 1,081 (421 to 2,028) |
Caribbean | 29,484 (14,661 to 46,004) | 27,773 (13,791 to 43,647) | 1,710 (728 to 3,224) |
Europe, Central | 137,495 (69,706 to 214,634) | 129,873 (65,902 to 202,094) | 7,621 (3,384 to 14,119) |
Europe, Eastern | 664,145 (321,237 to 1,063,148) | 639,605 (308,328 to 1,023,931) | 24,540 (10,754 to 43,824) |
Europe, Western | 284,320 (144,755 to 435,735) | 252,487 (127,659 to 387,169) | 31,833 (13,996 to 56,870) |
Latin America, Andean | 12,761 (6,305 to 20,517) | 11,495 (5,747 to 18,348) | 1,266 (529 to 2,470) |
Latin America, Central | 84,115(43,308 to 132,587) | 77,860 (39,465 to 122,414) | 6,255 (2,652 to 12,031) |
Latin America, Southern | 31,373 (15,066 to 53,307) | 28,547 (13,876 to 47,362) | 2,825 (1,140 to 5,412) |
Latin America, Tropical | 127,581 (65,215 to 208,633) | 115,548 (58,951 to 191,580) | 12,032 (5,224 to 21,858) |
North Africa/Middle East | 363,828 (183,937 to 571,914) | 342,820 (171,720 to 533,404) | 21,008 (9,630 to 37,854) |
North America, High Income | 244,716 (125,676 to 394,058) | 223,728 (114,409 to 358,292) | 20,987 (9,588 to 38,059) |
Oceania | 3,628 (1,751 to 6,339) | 3,355 (1,623 to 5,891) | 272 (107 to 507) |
SubSaharan Africa, Central | 28,336 (13,710 to 47,204) | 26,682 (12,849 to 44,673) | 1,653 (667 to 3,421) |
SubSaharan Africa, East | 62,438 (31,898 to 99,496) | 55,098 (28,007 to 88,043) | 7,340 (3,205 to 13,455) |
SubSaharan Africa, Southern | 18,385 (9,071 to 30,166) | 16,567 (8,175 to 27,355) | 1,817 (771 to 3,341) |
SubSaharan Africa, West | 54,615 (27,511 to 86,304) | 48,864 (24,879 to 76,381) | 5,750 (2,483 to 11,008) |
Global | 3,823,004 (1,942,771 to 5,778, 350) | 3,572,770 (1,791,433 to 5,411,987) | 250,233 (114,845 to 444,063) |