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Erschienen in: Journal of NeuroEngineering and Rehabilitation 1/2013

Open Access 01.12.2013 | Erratum

Erratum to: Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional near-infrared spectroscopy (fNIRS)

verfasst von: Lisa Holper, Thomas Muehlemann, Felix Scholkmann, Kynan Eng, Daniel Kiper, Martin Wolf

Erschienen in: Journal of NeuroEngineering and Rehabilitation | Ausgabe 1/2013

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Electronic supplementary material

The online version of this article (doi:10.​1186/​1743-0003-10-16) contains supplementary material, which is available to authorized users.
The online version of the original article can be found at 10.​1186/​1743-0003-7-57

Correction

Following publication of our article [1], we realised that some of the statistical tests used were not appropriate. We have now conducted the appropriate statistical tests, and updated the relevant tables, figures five and six (Figures 1 and 2 here, respectively) and conclusions accordingly.
For both the unilateral and the bilateral groups, analyses were recalculated.
Intra-condition differences:
  • original publication [1]: paired t-test using means per trial for unilateral and bilateral group
  • update: one-way repeated measures ANOVA using means per subject for unilateral and bilateral group
Inter-condition differences:
  • original publication [1]: one-way ANOVA using means per trial for unilateral and bilateral group
  • update: one-way repeated measures ANOVA using means per subject for unilateral and bilateral group

Conclusions

For the unilateral group (Table 1 and Figure 1), no changes in significance levels were found in Δ[O2Hb] signals. For the bilateral group (Table 2 and Figure 2), the main differences compared to the original publication are that the intra-condition differences ([O2Hb]rest versus [O2Hb]stim) for the two conditions ‘Observation Right’ (O_R, p = 0.077) and ‘Observation Left’ (O_L, p = 0.080) recorded over the ipsilateral hemisphere do not reach significant level any more. Hence, the paragraphs discussing the intra-condition significances in those two conditions (sections Observation, imagery and imitation and Bilateral oxygenation of the Discussion) are only applicable for the contralateral hemisphere. Further, in both groups changes in significance levels were found for Δ[HHb]. However, since the Discussion and Conclusion of the originally published article only focuses on the concentration changes found in Δ[O2Hb], this aspect does not change these sections.
Table 1
Unilateral group
Unilateral group [N = 15]
Observation
Motor imagery
Observation & motor imagery
Imitation
Left hemisphere (contralateral) (μmol/ l ± SD)
Mean ∆ [O2Hb]
0.06953 ± 0.1800
0.0833 ± 0.1404
0.0460 ± 0.2218
0.2309 ± 0.3212
Mean ∆ [HHb]
−0.0051 ± 0.03855
0.0356 ± 0.0771
−0.0089 ± 0.0963
0.0079 ± 0.0832
Intra-condition, ANOVA, repeated measures
   
[O2Hb] rest-stim
p = 0.157
p = 0.037*
p = 0.435
p = 0.015*
[HHb] rest-stim
p = 0.612
p = 0.097
p = 0.727
p = 0.717
Inter-condition ANOVA, repeated measures, post-hoc-tests, Bonferroni 0.05
[HHb]
[O 2 Hb]
 
 
O – MI
p = 0.347
p = 1.000
 
 
O – O&MI
p = 1.000
p = 1.000
 
 
O – IM
p = 1.000
p = 0.286
 
 
MI – O&MI
p = 0.132
p = 1.000
 
 
MI – IM
p = 1.000
p = 0.622
 
 
O&MI – IM
p = 1.000
p = 0.321
 
Main effect on condition
p = 0.253
p = 0.062
 
(Top) Mean signal amplitudes (μmol/l ± SD) of channels with significant concentration changes. Separate calculations for increases in [O2Hb], decreases in [HHb] in response to the four conditions for each group. Numbers were rounded to four decimal places. (Middle) Intra-condition statistical significance of the mean changes between [O2Hb]rest and [O2Hb]stim and [HHb]rest and [HHb]stim repeated measures ANOVA. (Bottom) Inter-condition statistical significance of mean changes of ∆ [O2Hb] and ∆ [HHb] between the four conditions using repeated measures ANOVA. Shown are post-hoc tests (with Bonferroni correction); significant values (p ≤ 0.05) are highlighted by * (observation = O, motor imagery = MI, observation & motor imagery = O & MI, imitation = IM).
Table 2
Bilateral group
Bilateral group [N = 8]
Observation right
Observation left
Imitation right
Imitation left
Left hemisphere (contralateral) (μmol/ l ± SD)
Mean ∆ [O2Hb]
0.1231 ± 0.1506
0.1231 ± 0.1507
0.3941 ± 0.4598
0.3715 ± 0.4289
Mean ∆ [HHb]
−0.0056 ± 0.0676
−0.0408 ± 0.0915
0.0371 ± 0.1131
0.0474 ± 0.0665
Intra-condition, ANOVA, repeated measures
[O2Hb] rest-stim
p = 0.044*
p = 0.047*
p = 0.025*
p = 0.038*
[HHb] rest-stim
p = 0.821
p = 0.247
p = 0.384
p = 0.084
Inter-condition, ANOVA, repeated measures, post-hoc-tests, Bonferroni 0.05
[HHb]
[O 2 Hb]
 
 
O_R – O_L
p = 1.000
p = 1.000
 
 
O_R – IM_R
p = 1.000
p = 0.519
 
 
O_R – IM_L
p = 1.000
p = 0.862
 
 
OL_ – IM_R
p = 0.227
p = 0.486
 
 
O_L – IM_L
p = 0.223
p = 0.777
 
 
IM_R – IM_L
p = 1.000
p = 1.000
 
Main effect on condition
p = 0.072
p = 0.119
 
Right hemisphere (ipsilateral) (μmol/ l ± SD)
Mean ∆ [O2Hb]
0.1541 ± 0.0735
0.1957 ± 0.1957
0.4036 ± 0.2097
1.3728 ± 1.6143
Mean ∆ [HHb]
−0.0113 ± 0.0334
0.0068 ± 0.0274
0.0235 ± 0.0402
0.7016 ± 1.9167
Intra-condition, ANOVA, repeated measures
   
[O2Hb] rest-stim
p = 0.077
p = 0.080
p = 0.002*
p = 0.032*
[HHb] rest-stim
p = 0.367
p = 0.502
p = 0.142
p = 0.335
Inter-condition, ANOVA, repeated measures, post-hoc-tests, Bonferroni 0.05
[HHb]
[O 2 Hb]
 
 
O_R – O_L
p = 1.000
p = 1.000
 
 
O_R – IM_R
p = 0.445
p = 0.014*
 
 
O_R – IM_L
p = 1.000
p = 0.324
 
 
OL_ – IM_R
p = 1.000
p = 0.015*
 
 
O_L – IM_L
p = 1.000
p = 0.231
 
 
IM_R – IM_L
p = 1.000
p = 0.710
 
Main effect on condition
p = 0.384
p = 0.008*
 
(Top) Mean signal amplitudes (μmol/l ± SD) of channels with significant concentration changes. Separate calculations for increases in [O2Hb], decreases in [HHb] in response to the four conditions for each group. Numbers were rounded to four decimal places. (Middle) Intra-condition statistical significance of the mean change between [O2Hb]rest and [O2Hb]stim and [HHb]rest and [HHb]stim using repeated measures ANOVA. (Bottom) Inter-condition statistical significance of mean changes of ∆ [O2Hb] and ∆ [HHb] between the four conditions using repeated measures ANOVA. Shown are post-hoc tests (with Bonferroni correction); significant values (p ≤ 0.05) are highlighted by * (observation left = O_L, observation right = O_R, imitation left = IM_L, imitation right = IM_R).
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://​creativecommons.​org/​licenses/​by/​2.​0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Literatur
1.
Zurück zum Zitat Holper L, et al: Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional near-infrared spectroscopy (fNIRS). J Neuroeng Rehabil. 2012, 7: 57-CrossRef Holper L, et al: Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional near-infrared spectroscopy (fNIRS). J Neuroeng Rehabil. 2012, 7: 57-CrossRef
Metadaten
Titel
Erratum to: Testing the potential of a virtual reality neurorehabilitation system during performance of observation, imagery and imitation of motor actions recorded by wireless functional near-infrared spectroscopy (fNIRS)
verfasst von
Lisa Holper
Thomas Muehlemann
Felix Scholkmann
Kynan Eng
Daniel Kiper
Martin Wolf
Publikationsdatum
01.12.2013
Verlag
BioMed Central
Erschienen in
Journal of NeuroEngineering and Rehabilitation / Ausgabe 1/2013
Elektronische ISSN: 1743-0003
DOI
https://doi.org/10.1186/1743-0003-10-16

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