Introduction
Methods and materials
Patient data and manual contouring
Automatic contouring
Time/speed evaluation
Quantitative evaluation of automated and manually corrected contours
Results
Time/speed evaluation
Anatomical sites | Manual contouring time (SD) | Software | Automatic contouring time (SD) | Manual corrections time (SD) | Automatic+corrections |
---|---|---|---|---|---|
PROSTATE | 1.18.37 (0.09.23) | ABAS | 0.14.51 (0.00.39) | 0.32.42 (0.06.37) * ° | * § = |
MIM | 0.02.34 (0.00.12) | 0.20.31 (0.05.12) * # + | * % = | ||
VELOCITY AI | 0.08.23 (0.00.16) | 0.28.35 (0.05.40) * ° | * % § | ||
HEAD & NECK | 2.43.12 (0.48.21) | ABAS | 0.10.58 (0.02.21) | 1.09.15 (0.13.49) * ° + | * § = |
MIM | 0.03.46 (0.00.35) | 1.35.30 (0.17.11) * # | * % | ||
VELOCITY AI | 0.06.21 (0.00.37) | 1.52.30 (0.5.46) * # | * % | ||
MESOTHELIOMA | 1.21.02 (0.05.00) | ABAS | 0.08.32 (0.00.17) | 0.50.24 (0.03.35) * ° # | * = |
MIM | 0.02.35 (0.00.17) | 0.56.00 (0.02.21) * # | * | ||
VELOCITY AI | 0.06.47 (0.00.22) | 0.59.36 (0.09.04) * # | * % |
Contour evaluation
AA | MA | VA | AM | MM | VM | p value | |
---|---|---|---|---|---|---|---|
CTV1
| |||||||
DSC, (SD) | 0.86 (0.08) | 0.79 (0.05) | 0.76 (0.14) | 0.88 (0.09) | 0.81 (0.04) | 0.82 (0.02) | |
Sensitivity, (SD) | 0.82 (0.11) | 0.72 (0.11) | 0.70 (0.20) | 0.85 (0.11) | 0.76 (0.09) | 0.82 (0.07) | |
IncI, (SD) | 0.92 (0.05) | 0.89 (0.07) | 0.85 (0.06) | 0.91 (0.06) | 0.88 (0.03) | 0.84 (0.07) | * |
ΔV (%), (SD) | −11.48 (7.83) | −17.83 (17.60) | −17.70 (23.61) | −7.73 (6.32) | −13.15 (12.11) | −1.30 (15.18) | ° |
Δx (mm), (SD) | 0.45 (0.33) | 0.35 (0.24) | 0.38 (0.52) | 0.35 (0.24) | 0.55 (0.40) | 0.85 (0.58) | |
Δy (mm), (SD) | 0.60 (0.64) | 0.93 (0.56) | 0.68 (0.56) | 1.03 (1.01) | 0.83 (0.50) | 0.88 (0.90) | |
Δz (mm), (SD) | 1.25 (1.44) | 3.18 (2.39) | 1.88 (1.25) | 1.28 (1.02) | 2.23 (1.19) | 2.20 (0.60) | |
CTV2
| |||||||
DSC, (SD) | 0.77 (0.06) | 0.86 (0.01) | 0.83 (0.02) | 0.87 (0.08) | 0.87 (0.01) | 0.84 (0.01) | * ° = |
Sensitivity, (SD) | 0.67 (0.12) | 0.87 (0.02) | 0.84 (0.03) | 0.86 (0.09) | 0.87 (0.03) | 0.85 (0.03) | * ° = |
IncI, (SD) | 0.93 (0.06) | 0.85 (0.02) | 0.82 (0.04) | 0.88 (0.08) | 0.86 (0.03) | 0.84 (0.02) | * # |
ΔV (%), (SD) | −27.46 (17.74) | 2.54 (4.98) | 2.78 (8.47) | −1.44 (8.11) | 1.88 (7.6) | 2.12 (6.31) | * # |
Δx (mm), (SD) | 1.63 (1.37) | 0.45 (0.41) | 0.35 (0.47) | 0.98 (1.13) | 0.48 (0.41) | 0.58 (0.22) | |
Δy (mm), (SD) | 3.54 (1.28) | 2.58 (0.92) | 2.55 (1.30) | 2.23 (2.62) | 2.85 (0.93) | 2.68 (1.03) | |
Δz (mm), (SD) | 1.28 (1.79) | 1.28 (1.79) | 1.90 (1.62) | 1.58 (1.90) | 2.23 (1.85) | 1.90 (1.63) | |
Rectum
| |||||||
DSC, (SD) | 0.77 (0.07) | 0.75 (0.09) | 0.75 (0.04) | 0.90 (0.07) | 0.87 (0.05) | 0.86 (0.05) | |
Sensitivity, (SD) | 0.88 (0.06) | 0.70 (0.17) | 0.72 (0.13) | 0.92 (0.08) | 0.89 (0.05) | 0.87 (0.07) | * # ^ |
IncI , (SD) | 0.69 (0.11) | 0.84 (0.06) | 0.79 (0.08) | 0.88 (0.07) | 0.86 (0.09) | 0.86 (0.09) | |
ΔV (%), (SD) | 30.2 (24.30) | −15.38 (24.1) | −7.06 (23.65) | 4.7 (10.10) | 5.2 (13.88) | 2.34 (16.64) | * ° |
Δx (mm), (SD) | 2.00 (1.78) | 2.14 (1.46) | 3.36 (1.70) | 1.30 (2.11) | 0.720 (0.71) | 1.92 (1.70) | |
Δy (mm), (SD) | 2.74 (1.81) | 1.36 (0.85) | 1.50 (1.71) | 1.44 (1.15) | 0.90 (0.30) | 1.16 (0.76) | |
Δz (mm), (SD) | 6.54 (5.33) | 6.02 (5.25) | 6.04 (4.16) | 3.78 (4.05) | 6.8 (3.71) | 7.28 (5.11) | ^ |
Bladder
| |||||||
DSC, (SD) | 0.93 (0.03) | 0.88 (0.07) | 0.72 (0.15) | 0.95 (0.04) | 0.93 (0.02) | 0.93 (0.02) | # ° |
Sensitivity, (SD) | 0.93 (0.03) | 0.88 (0.12) | 0.67 (0.25) | 0.96 (0.03) | 0.96 (0.03) | 0.93 (0.05) | = |
IncI, (SD) | 0.92 (0.06) | 0.89 (0.04) | 0.89 (0.13) | 0.94 (0.04) | 0.91 (0.03) | 0.93 (0.05) | + |
ΔV (%), (SD) | 1.88 (8.29) | −1.70 (14.87) | −20.24 (43.21) | 2.40 (3.90) | 6.12 (5.89) | 0.20 (8.79) | = |
Δx (mm), (SD) | 1.10 (0.16) | 0.46 (0.46) | 0.90 (0.67) | 0.66 (0.53) | 0.46 (0.46) | 0.86 (1.01) | |
Δy (mm), (SD) | 1.32 (1.53) | 3.42 (3.98) | 3.44 (4.06) | 0.52 (0.56) | 0.72 (0.57) | 0.76 (0.34) | |
Δz (mm), (SD) | 1.80 (0.66) | 2.02 (1.12) | 5.02 (2.92) | 2.02 (2.28) | 1.80 (1.19) | 2.02 (1.43) | ^ |
Bowel
| |||||||
DSC, (SD) | 0.83 (0.10) | 0.85 (0.09) | 0.88 (0.03) | 0.89 (0.12) | 0.92 (0.02) | 0.87 (0.09) | = |
Sensitivity, (SD) | 0.79 (0.15) | 0.82 (0.14) | 0.88 (0.03) | 0.88 (0.18) | 0.94 (0.02) | 0.84 (0.15) | = |
IncI, (SD) | 0.89 (0.08) | 0.90 (0.04) | 0.88 (0.05) | 0.91 (0.05) | 0.91 (0.03) | 0.91 (0.01) | |
ΔV (%), (SD) | −10.78 (17.74) | −9.12 (14.13) | −0.10 (6.50) | −3.38 (18.54) | 2.36 (2.98) | −7.82 (15.27) | |
Δx (mm), (SD) | 3.44 (2.63) | 2.58 (1.84) | 3.32 (3.06) | 2.16 (1.79) | 2.98 (1.40) | 3.46 (3.36) | |
Δy (mm), (SD) | 8.42 (3.68) | 6.88 (3.90) | 5.34 (3.72) | 4.20 (5.56) | 7.48 (3.82) | 4.78 (5.87) | |
Δz (mm), (SD) | 9.78 (10.21) | 9.78 (12.15) | 6.28 (4.43) | 6.02 (11.39) | 0.26 (0.58) | 5.00 (11.18) | |
Femoral head right
| |||||||
DSC, (SD) | 0.94 (0.04) | 0.94 (0.02) | 0.92 (0.03) | 0.94 (0.04) | 0.94 (0.01) | 0.93 (0.02) | # ° = |
Sensitivity, (SD) | 0.94 (0.05) | 0.96 (0.02) | 0.94 (0.03) | 0.94 (0.05) | 0.95 (0.02) | 0.95 (0.03) | ° |
IncI , (SD) | 0.94 (0.04) | 0.93 (0.03) | 0.90 (0.04) | 0.95 (0.04) | 0.93 (0.03) | 0.91 (0.03) | * # ° + ^ = |
ΔV (%), (SD) | 0.12 (4.98) | 2.92 (4.63) | 4.82 (4.53) | −0.18 (4.92) | 2.76 (4.98) | 4.22 (5.08) | ° |
Δx (mm), (SD) | 0.16 (0.36) | 0.36 (0.21) | 0.46 (0.49) | 0.16 (0.36) | 0.36 (0.21) | 0.64 (0.31) | |
Δy (mm), (SD) | 0.18 (0.25) | 0.36 (0.38) | 0.74 (0.51) | 0.26 (0.24) | 0.36 (0.38) | 0.92 (0.67) | |
Δz (mm), (SD) | 1.76 (1.11) | 1.76 (1.70) | 1.76 (2.09) | 1.78 (1.43) | 2.02 (0.66) | 2.04 (1.11) | |
Femoral head left
| |||||||
DSC, (SD) | 0.94 (0.04) | 0.94 (0.03) | 0.92 (0.02) | 0.94 (0.04) | 0.94 (0.02) | 0.92 (0.03) | * # ^ |
Sensitivity, (SD) | 0.95 (0.04) | 0.96 (0.02) | 0.94 (0.02) | 0.95 (0.04) | 0.96 (0.02) | 0.95 (0.03) | ° = |
IncI , (SD) | 0.93 (0.05) | 0.92 (0.05) | 0.90 (0.04) | 0.94 (0.05) | 0.92 (0.04) | 0.90 (0.05) | # ^ |
ΔV (%), (SD) | 2.30 (5.73) | 4.92 (6.06) | 5.42 (6.47) | 1.24 (6.01) | 4.94 (5.70) | 4.94 (7.35) | * # + ^ |
Δx (mm), (SD) | 0.62 (0.91) | 0.68 (0.67) | 0.66 (0.49) | 0.62 (0.91) | 0.68 (0.67) | 0.76 (0.44) | |
Δy (mm), (SD) | 0.16 (0.36) | 0.36 (0.38) | 0.64 (0.31) | 0.16 (0.36) | 0.36 (0.38) | 0.76 (0.51) | |
Δz (mm), (SD) | 3.28 (1.91) | 2.26 (1.85) | 2.02 (1.92) | 2.02 (1.43) | 1.52 (1.04) | 2.30 (1.37) |
AA | MA | VA | AM | MM | VM | p value | |
---|---|---|---|---|---|---|---|
CTV1
| |||||||
DSC, (SD) | 0.68 (0.19) | 0.67 (0.17) | 0.66 (0.18) | 0.72 (0.15) | 0.76 (0.11) | 0.71 (0.09) | # |
Sensitivity, (SD) | 0.73 (0.23) | 0.76 (0.19) | 0.74 (0.22) | 0.79 (0.18) | 0.85 (0.10) | 0.81 (0.16) | |
IncI, (SD) | 0.64 (0.17) | 0.61 (0.18) | 0.60 (0.17) | 0.67 (0.13) | 0.69 (0.13) | 0.65 (0.09) | * # |
ΔV (%), (SD) | 14.10 (25.99) | 25.92 (21.18) | 23.28 (28.44) | 17.72 (22.19) | 24.94 (26.01) | 27.40 (32.49) | |
Δx (mm), (SD) | 2.62 (2.02) | 2.92 (1.76) | 2.44 (1.58) | 2.12 (1.45) | 2.70 (1.03) | 2.88 (2.42) | |
Δy (mm), (SD) | 2.58 (2.70) | 2.66 (2.72) | 2.86 (2.37) | 2.60 (2.47) | 2.74 (2.47) | 5.30 (3.32) | |
Δz (mm), (SD) | 5.40 (7.98) | 5.70 (5.65) | 5.10 (5.77) | 5.40 (7.98) | 3.60 (5.67) | 4.80 (5.02) | |
CTV2
| |||||||
DSC, (SD) | 0.84 (0.03) | 0.83 (0.03) | 0.81 (0.02) | 0.85 (0.03) | 0.84 (0.03) | 0.82 (0.03) | |
Sensitivity, (SD) | 0.85 (0.04) | 0.86 (0.05) | 0.85 (0.05) | 0.86 (0.04) | 0.88 (0.04) | 0.86 (0.04) | |
IncI, (SD) | 0.83 (0.06) | 0.81 (0.06) | 0.78 (0.05) | 0.83 (0.06) | 0.81 (0.06) | 0.78 (0.06) | |
ΔV (%), (SD) | 3.50 (11.31) | 7.40 (13.33) | 10.00 (12.34) | 4.45 (10.20) | 8.38 (11.57) | 10.68 (12.51) | |
Δx (mm), (SD) | 2.95 (2.30) | 2.85 (1.85) | 3.08 (1.81) | 2.48 (2.56) | 2.95 (1.80) | 3.38 (1.37) | |
Δy (mm), (SD) | 2.38 (0.69) | 3.73 (2.50) | 2.53 (1.94) | 2.23 (0.95) | 3.60 (2.54) | 2.90 (1.51) | |
Δz (mm), (SD) | 1.50 (1.23) | 1.50 (2.12) | 1.88 (2.25) | 1.50 (1.23) | 1.88 (1.44) | 2.63 (1.44) | |
Larynx
| |||||||
DSC, (SD) | 0.86 (0.04) | 0.87 (0.01) | 0.82 (0.04) | 0.90 (0.03) | 0.89 (0.02) | 0.86 (0.05) | |
Sensitivity, (SD) | 0.87 (0.06) | 0.88 (0.03) | 0.85 (0.06) | 0.92 (0.04) | 0.93 (0.01) | 0.91 (0.02) | |
IncI, (SD) | 0.86 (0.03) | 0.85 (0.03) | 0.80 (0.05) | 0.87 (0.02) | 0.85 (0.02) | 0.82 (0.08) | |
ΔV (%), (SD) | 1.43 (5.92) | 3.85 (6.75) | 5.83 (9.59) | 5.15 (3.37) | 8.55 (1.93) | 11.20 (11.32) | |
Δx (mm), (SD) | 0.65 (0.51) | 0.38 (0.48) | 0.88 (0.48) | 0.90 (0.52) | 0.53 (0.61) | 0.50 (0.00) | |
Δy (mm), (SD) | 0.38 (0.25) | 0.75 (0.65) | 0.40 (0.80) | 0.38 (0.25) | 0.50 (0.58) | 0.90 (0.52) | |
Δz (mm), (SD) | 5.63 (3.75) | 9.75 (5.81) | 3.75 (4.50) | 0.75 (0.87) | 1.50 (1.23) | 0.75 (1.50) | |
Sup. Pharynx
| |||||||
DSC, (SD) | 0.36 (0.22) | 0.35 (0.12) | 0.33 (0.13) | 0.57 (0.05) | 0.50 (0.14) | 0.52 (0.11) | |
Sensitivity, (SD) | 0.49 (0.38) | 0.51 (0.35) | 0.47 (0.32) | 0.74 (0.10) | 0.80 (0.11) | 0.76 (0.11) | |
IncI, (SD) | 0.42 (0.14) | 0.42 (0.26) | 0.40 (0.23) | 0.49 (0.13) | 0.40 (0.20) | 0.42 (0.19) | |
ΔV (%), (SD) | 27.70 (90.39) | 67.50 (125.10) | 57.25 (112.28) | 61.63 (48.64) | 146.60 (134.73) | 107.58 (96.01) | |
Δx (mm), (SD) | 1.18 (1.41) | 1.43 (1.27) | 1.73 (2.45) | 0.98 (0.95) | 0.75 (0.50) | 1.03 (0.82) | |
Δy (mm), (SD) | 1.88 (1.38) | 1.90 (1.04) | 3.23 (3.78) | 1.13 (0.90) | 1.48 (1.63) | 1.88 (1.74) | |
Δz (mm), (SD) | 6.00 (3.24) | 6.75 (3.12) | 4.88 (3.75) | 3.00 (1.73) | 4.50 (2.12) | 3.38 (3.09) | |
Mid. Pharynx
| |||||||
DSC, (SD) | 0.57 (0.10) | 0.56 (0.13) | 0.43 (0.19) | 0.61 (0.09) | 0.60 (0.12) | 0.62 (0.12) | |
Sensitivity, (SD) | 0.52 (0.12) | 0.57 (0.17) | 0.44 (0.19) | 0.59 (0.12) | 0.68 (0.15) | 0.64 (0.13) | ° |
IncI, (SD) | 0.65 (0.13) | 0.56 (0.12) | 0.44 (0.21) | 0.64 (0.10) | 0.55 (0.13) | 0.61 (0.11) | * # |
ΔV (%), (SD) | −18.94 (18.43) | 4.62 (27.73) | 4.12 (37.64) | −7.48 (16.77) | 27.38 (34.84) | 4.66 (9.21) | * + |
Δx (mm), (SD) | 0.60 (0.82) | 0.80 (0.45) | 1.20 (1.11) | 0.90 (0.82) | 0.80 (0.45) | 0.70 (0.57) | |
Δy (mm), (SD) | 3.32 2.64() | 2.78 (1.08) | 2.64 (2.256) | 3.02 (2.78) | 2.76 (2.32) | 1.68 (1.29) | |
Δz (mm), (SD) | 4.20 (4.55) | 3.90 (4.70) | 4.80 (5.13) | 4.20 (4.42) | 5.40 (4.81) | 5.10 (5.37) | |
Inf. Pharynx
| |||||||
DSC, (SD) | 0.65 (0.07) | 0.66 (0.05) | 0.63 (0.07) | 0.71 (0.04) | 0.72 (0.03) | 0.72 (0.04) | |
Sensitivity, (SD) | 0.59 (0.08) | 0.65 (0.08) | 0.60 (0.09) | 0.67 (0.04) | 0.72 (0.10) | 0.73 (0.07) | * |
IncI, (SD) | 0.75 (0.11) | 0.69 (0.07) | 0.66 (0.09) | 0.75 (0.10) | 0.72 (0.05) | 0.72 (0.09) | # ^ |
ΔV (%), (SD) | −20.04 (15.57) | −5.58 (17.12) | −7.46 (16.01) | −9.96 (14.02) | 1.62 (19.64) | 3.22 (18.60) | * # |
Δx (mm), (SD) | 1.12 (0.44) | 0.72 (0.47) | 0.90 (0.65) | 0.60 (0.55) | 0.50 (0.50) | 0.70 (0.48) | |
Δy (mm), (SD) | 2.06 (2.28) | 1.62 (1.63) | 1.38 (1.43) | 1.90 (2.12) | 1.52 (0.61) | 1.28 (2.07) | |
Δz (mm), (SD) | 3.90 (3.29) | 2.70 (1.26) | 3.00 (3.82) | 4.50 (3.52) | 4.20 (2.47) | 2.70 (3.25) | |
Thyroid
| |||||||
DSC, (SD) | 0.73 (0.11) | 0.77 (0.06) | 0.73 (0.07) | 0.81 (0.05) | 0.82 (0.06) | 0.82 (0.05) | ^ |
Sensitivity, (SD) | 0.79 (0.15) | 0.81 (0.10) | 0.79 (0.08) | 0.86 (0.08) | 0.84 (0.05) | 0.84 (0.04) | |
IncI, (SD) | 0.69 (0.11) | 0.75 (0.10) | 0.70 (0.11) | 0.78 (0.10) | 0.81 (0.10) | 0.80 (0.07) | ° |
ΔV (%), (SD) | 14.86 (23.01) | 10.34 (28.54) | 15.70 (26.54) | 14.00 (25.25) | 5.72 (17.65) | 5.98 (9.27) | ° |
Δx (mm), (SD) | 0.98 (0.82) | 1.26 (1.51) | 1.48 (1.37) | 0.50 (0.00) | 0.70 (0.98) | 1.56 (1.93) | |
Δy (mm), (SD) | 1.18 (1.06) | 0.98 (0.90) | 1.68 (2.12) | 0.70 (0.45) | 0.40 (0.42) | 0.60 (0.55) | |
Δz (mm), (SD) | 3.00 (2.37) | 2.10 (2.28) | 1.50 (1.50) | 2.70 (2.47) | 1.20 (1.96) | 2.10 (1.34) | |
Masticator space right
| |||||||
DSC, (SD) | 0.80 (0.04) | 0.82 (0.03) | 0.80 (0.03) | 0.85 (0.02) | 0.84 (0.04) | 0.84 (0.02) | ° |
Sensitivity, (SD) | 0.79 (0.07) | 0.84 (0.03) | 0.80 (0.06) | 0.83 (0.07) | 0.91 (0.02) | 0.86 (0.03) | ° + = |
IncI, (SD) | 0.84 (0.10) | 0.80 (0.03) | 0.80 (0.02) | 0.86 (0.05) | 0.79 (0.07) | 0.82 (0.02) | + ^ |
ΔV (%), (SD) | −3.52 (21.72) | 4.74 (3.43) | −0.62 (6.99) | −3.16 (12.28) | 16.28 (12.24) | 5.14 (2.48) | ° = |
Δx (mm), (SD) | 0.82 (0.58) | 1.00 (0.5) | 0.82 (0.58) | 0.50 (0.71) | 0.90 (0.82) | 0.82 (0.30) | |
Δy (mm), (SD) | 1.12 (0.69) | 1.20 (0.99) | 1.20 (1.29) | 1.02 (0.36) | 1.78 (1.85) | 1.30 (1.19) | |
Δz (mm), (SD) | 3.30 (1.64) | 4.80 (5.13) | 5.40 (4.70) | 2.70 (0.67) | 3.00 (3.52) | 2.70 (1.64) | |
Masticator Space left
| |||||||
DSC, (SD) | 0.79 (0.05) | 0.81 (0.05) | 0.77 (0.05) | 0.86 (0.02) | 0.86 (0.03) | 0.85 (0.02) | * # ° |
Sensitivity, (SD) | 0.72 (0.08) | 0.79 (0.08) | 0.73 (0.09) | 0.82 (0.05) | 0.89 (0.03) | 0.86 (0.04) | * ° + ^ |
IncI, (SD) | 0.89 (0.05) | 0.85 (0.01) | 0.82 (0.01) | 0.90 (0.02) | 0.83 (0.07) | 0.84 (0.03) | ° + ^ |
ΔV (%), (SD) | −18.64 (12.32) | −7.02 (10.16) | −10.58 (12.18) | −8.30 (5.83) | 8.26 (10.51) | 3.00 (5.82) | ° + ^ |
Δx (mm), (SD) | 0.84 (1.34) | 1.02 (0.65) | 1.02 (0.82) | 1.040 (0.96) | 0.92 (0.58) | 0.62 (0.69) | |
Δy (mm), (SD) | 2.26 (1.85) | 1.76 (1.27) | 2.12 (0.80) | 1.820 (1.08) | 2.52 (2.76) | 1.94 (1.37) | |
Δz (mm), (SD) | 3.00 (2.60) | 6.00 (5.09) | 6.00 (5.91) | 2.40 (0.82) | 3.00 (4.37) | 2.40 (1.34) | |
Mandible
| |||||||
DSC, (SD) | 0.89 (0.02) | 0.86 (0.02) | 0.84 (0.02) | 0.90 (0.02) | 0.89 (0.02) | 0.89 (0.02) | * |
Sensitivity, (SD) | 0.87 (0.05) | 0.86 (0.04) | 0.82 (0.04) | 0.88 (0.04) | 0.92 (0.03) | 0.92 (0.03) | + ^ |
IncI, (SD) | 0.92 (0.02) | 0.86 (0.05) | 0.86 (0.06) | 0.92 (0.02) | 0.86 (0.05) | 0.87 (0.05) | * # + ^ |
ΔV (%), (SD) | −4.76 (7.12) | −0.48 (9.51) | −3.60 (12.00) | −3.88 (6.02) | 7.06 (9.05) | 7.02 (8.78) | |
Δx (mm), (SD) | 0.30 (0.27) | 0.60 (0.42) | 0.50 (0.35) | 0.30 (0.27) | 0.70 (0.57) | 0.30 (0.27) | |
Δy (mm), (SD) | 0.30 (0.27) | 0.40 (0.22) | 0.50 (0.35) | 0.30 (0.27) | 0.30 (0.27) | 0.20 (0.27) | |
Δz (mm), (SD) | 0.60 (0.82) | 0.30 (0.67) | 1.20 (1.26) | 0.90 (0.82) | 0.60 (0.82) | 0.60 (0.82) | |
Spinal cord
| |||||||
DSC, (SD) | 0.70 (0.10) | 0.81 (0.05) | 0.78 (0.06) | 0.84 (0.02) | 0.87 (0.01) | 0.86 (0.01) | * |
Sensitivity, (SD) | 0.60 (0.14) | 0.78 (0.10) | 0.75 (0.08) | 0.78 (0.05) | 0.87 (0.03) | 0.88 (0.04) | * # |
IncI, (SD) | 0.89 (0.07) | 0.86 (0.07) | 0.83 (0.08) | 0.91 (0.05) | 0.87 (0.02) | 0.84 (0.03) | |
ΔV (%), (SD) | −32.46 (19.30) | −9.00 (16.93) | −8.40 (14.92) | −13.18 (9.26) | 0.66 (4.55) | 5.52 (8.34) | * # + ^ |
Δx (mm), (SD) | 0.80 (0.45) | 0.60 (0.22) | 0.92 (0.66) | 1.00 (0.80) | 0.90 (0.42) | 0.30 (0.27) | |
Δy (mm), (SD) | 3.62 (6.98) | 4.88 (7.20) | 2.78 (3.96) | 0.92 (0.43) | 0.32 (0.72) | 0.62 (0.59) | |
Δz (mm), (SD) | 7.80 (11.74) | 7.20 (12.79) | 6.00 (10.92) | 0.60 (0.82) | 0.30 (0.67) | 0.00 (0.00) | |
Parotid gland right
| |||||||
DSC, (SD) | 0.78 (0.08) | 0.79 (0.07) | 0.73 (0.08) | 0.80 (0.06) | 0.82 (0.05) | 0.80 (0.05) | # ° = |
Sensitivity, (SD) | 0.79 (0.13) | 0.82 (0.12) | 0.79 (0.16) | 0.82 (0.12) | 0.86 (0.10) | 0.84 (0.10) | + |
IncI, (SD) | 0.80 (0.11) | 0.77 (0.09) | 0.71 (0.08) | 0.80 (0.09) | 0.79 (0.07) | 0.79 (0.10) | # |
ΔV (%), (SD) | −1.06 (21.92) | 8.96 (21.67) | 13.02 (29.54) | 4.40 (22.94) | 10.40 (18.23) | 9.14 (23.61) | * |
Δx (mm), (SD) | 1.50 (1.00) | 1.62 (1.24) | 2.02 (1.06) | 1.96 (1.79) | 1.62 (1.24) | 1.94 (1.19) | |
Δy (mm), (SD) | 6.46 (7.06) | 5.64 (5.66) | 6.58 (6.25) | 6.4 (7.11) | 4.32 (6.34) | 5.76 (7.04) | |
Δz (mm), (SD) | 2.40 (0.82) | 2.40 (0.82) | 3.60 (2.51) | 1.80 (1.26) | 1.50 (1.06) | 1.20 (1.64) | |
Parotid gland left
| |||||||
DSC, (SD) | 0.79 (0.07) | 0.78 (0.08) | 0.73 (0.04) | 0.80 (0.07) | 0.81 (0.06) | 0.81 (0.05) | ° |
Sensitivity, (SD) | 0.77 (0.11) | 0.79 (0.11) | 0.77 (0.05) | 0.79 (0.11) | 0.83 (0.09) | 0.85 (0.07) | ^ |
IncI, (SD) | 0.82 (0.07) | 0.77 (0.11) | 0.69 (0.04) | 0.82 (0.09) | 0.80 (0.11) | 0.78 (0.08) | # |
ΔV (%), (SD) | −5.84 (17.41) | 4.44 (20.36) | 12.96 (4.75) | −1.88 (21.29) | 6.54 (21.64) | 9.78 (14.61) | * |
Δx (mm), (SD) | 2.00 (1.46) | 2.46 (1.23) | 2.12 (1.43) | 2.12 (1.62) | 2.08 (1.46) | 3.08 (1.75) | ^ |
Δy (mm), (SD) | 1.68 (2.21) | 2.60 (1.37) | 2.12 (1.76) | 1.38 (1.60) | 0.78 (1.21) | 1.38 (2.00) | |
Δz (mm), (SD) | 3.60 (2.73) | 3.30 (2.68) | 4.50 (1.50) | 2.70 (1.96) | 3.60 (2.73) | 2.70 (2.23) | |
Cochlea right
| |||||||
DSC, (SD) | 0.63 (0.13) | 0.63 (0.17) | 0.46 (0.16) | 0.80 (0.03) | 0.77 (0.10) | 0.69 (0.07) | # ° ^ |
Sensitivity, (SD) | 0.59 (0.17) | 0.68 (0.24) | 0.42 (0.13) | 0.77 (0.09) | 0.84 (0.11) | 0.80 (0.10) | # ° |
IncI, (SD) | 0.71 (0.17) | 0.64 (0.23) | 0.55 (0.25) | 0.88 (0.09) | 0.72 (0.07) | 0.64 (0.14) | # + ^ |
ΔV (%), (SD) | −5.28 (6.84) | 16.94 (54.41) | −15.74 (23.04) | −7.36 (17.40) | 17.9 (21.82) | 33.98 (49.56) | + |
Δx (mm), (SD) | 0.90 (0.42) | 0.72 (0.47) | 1.28 (1.11) | 0.42 (0.24) | 0.62 (0.69) | 0.72 (0.88) | |
Δy (mm), (SD) | 1.38 (1.77) | 1.38 (1.20) | 1.60 (1.90) | 0.40 (0.42) | 0.30 (0.27) | 0.72 (0.30) | |
Δz (mm), (SD) | 0.50 (0.71) | 0.90 (0.82) | 2.40 (2.01) | 0.40 (0.65) | 0.30 (0.67) | 0.90 (0.82) | |
Cochlea left
| |||||||
DSC, (SD) | 0.52 (0.16) | 0.69 (0.10) | 0.59 (0.07) | 0.78 (0.07) | 0.78 (0.04) | 0.72 (0.07) | ° |
Sensitivity, (SD) | 0.45 (0.22) | 0.69 (0.13) | 0.58 (0.07) | 0.69 (0.09) | 0.81 (0.05) | 0.75 (0.08) | * + |
IncI, (SD) | 0.87 (0.10) | 0.70 (0.15) | 0.63 (0.13) | 0.92 (0.05) | 0.76 (0.09) | 0.72 (0.16) | * # + ^ |
ΔV (%), (SD) | −51.04 (29.55) | 6.06 (30.04) | −5.40 (13.70) | −23.32 (10.44) | 10.24 (12.62) | 11.50 (34.88) | * + ^ |
Δx (mm), (SD) | 1.00 (0.50) | 0.60 (0.42) | 1.00 (0.71) | 0.30 (0.27) | 0.40 (0.22) | 0.50 (0.50) | |
Δy (mm), (SD) | 0.40 (0.42) | 0.40 (0.42) | 0.90 (0.55) | 0.60 (0.55) | 0.20 (0.45) | 1.00 (0.50) | = |
Δz (mm), (SD) | 0.90 (0.82) | 1.00 (1.28) | 1.00 (1.28) | 0.30 (0.67) | 1.20 (1.26) | 0.40 (0.65) | |
Brain stem
| |||||||
DSC, (SD) | 0.80 (0.07) | 0.81 (0.11) | 0.77 (0.15) | 0.88 (0.02) | 0.88 (0.03) | 0.89 (0.03) | |
Sensitivity, (SD) | 0.74 (0.09) | 0.76 (0.17) | 0.73 (0.22) | 0.86 (0.04) | 0.86 (0.08) | 0.89 (0.03) | |
IncI, (SD) | 0.89 (0.06) | 0.89 (0.03) | 0.85 (0.03) | 0.90 (0.02) | 0.90 (0.03) | 0.88 (0.04) | |
ΔV (%), (SD) | −17.50 (8.23) | −14.36 (19.96) | −13.68 (26.28) | −4.54 (6.22) | −4.00 (10.88) | 1.44 (1.75) | ^ |
Δx (mm), (SD) | 0.70 (0.57) | 1.32 (0.78) | 1.12 (0.69) | 0.60 (0.22) | 0.92 (0.86) | 1.04 (1.02) | |
Δy (mm), (SD) | 1.40 (0.82) | 1.76 (0.80) | 1.88 (0.74) | 0.68 (0.82) | 0.90 (1.34) | 1.10 (0.67) | |
Δz (mm), (SD) | 2.40 (3.29) | 3.00 (3.82) | 4.20 (4.67) | 0.90 (0.82) | 0.90 (1.34) | 0.30 () | |
Esophagus
| |||||||
DSC, (SD) | 0.63 (0.10) | 0.65 (0.15) | 0.64 (0.13) | 0.83 (0.05) | 0.84 (0.06) | 0.83 (0.06) | |
Sensitivity, (SD) | 0.57 (0.15) | 0.57 (0.19) | 0.63 (0.17) | 0.85 (0.06) | 0.87 (0.04) | 0.88 (0.02) | |
IncI, (SD) | 0.76 (0.12) | 0.79 (0.09) | 0.67 (0.11) | 0.82 (0.10) | 0.82 (0.11) | 0.79 (0.10) | ° |
ΔV (%), (SD) | −21.68 (29.94) | −27.04 (26.22) | −5.92 (23.75) | 5.62 (18.34) | 8.26 (18.26) | 12.04 (12.37) | |
Δx (mm), (SD) | 1.12 (0.42) | 1.38 (1.05) | 1.54 (0.86) | 0.60 (0.65) | 0.80 (0.57) | 1.00 (0.79) | |
Δy (mm), (SD) | 3.84 (5.83) | 4.54 (6.48) | 3.66 (3.77) | 0.82 (0.84) | 1.12 (0.76) | 0.72 (0.79) | |
Δz (mm), (SD) | 7.80 (11.64) | 7.50 (12.68) | 6.60 (10.64) | 1.50 (1.06) | 1.20 (1.26) | 1.20 (1.26) |
AA | MA | VA | AM | MM | VM | p value | |
---|---|---|---|---|---|---|---|
CTV
| |||||||
DSC, (SD) | 0.85 (0.02) | 0.86 (0.02) | 0.85 (0.02) | 0.85 (0.02) | 0.94 (0.04) | 0.91 (0.02) | + ^ |
Sensitivity. (SD) | 0.92 (0.03) | 0.90 (0.02) | 0.91 (0.02) | 0.92 (0.03) | 0.93 (0.03) | 0.94 (0.03) | * ° ^ |
IncI. (SD) | 0.79 (0.02) | 0.82 (0.02) | 0.80 (0.02) | 0.80 (0.02) | 0.95 (0.06) | 0.87 (0.02) | * ° + ^ = |
ΔV (%). (SD) | 15.54 (1.53) | 9.26 (2.06) | 13.48 (2.45) | 14.90 (1.45) | −1.78 (4.95) | 8.10 (3.04) | * ° + ^ = |
Δx (mm). (SD) | 3.42 (4.20) | 3.42 (2.79) | 4.10 (2.24) | 4.20 (4.24) | 0.98 (1.24) | 3.40 (2.51) | = |
Δy (mm). (SD) | 3.82 (3.60) | 3.92 (3.61) | 3.52 (3.90) | 3.54 (3.69) | 1.78 (1.56) | 2.36 (1.51) | |
Δz (mm). (SD) | 4.00 (4.87) | 4.00 (4.87) | 4.50 (4.80) | 4.00 (3.35) | 0.50 (1.12) | 0.00 (0.00) | ^ |
Contra lateral lung
| |||||||
DSC. (SD) | 0.95 (0.03) | 0.94 (0.03) | 0.94 (0.02) | 0.97 (0.01) | 0.98 (0.01) | 0.99 (0.01) | ^ = |
Sensitivity. (SD) | 0.93 (0.05) | 0.90 (0.06) | 0.92 (0.04) | 0.97 (0.01) | 0.97 (0.01) | 0.99 (0.01) | ° ^ = |
IncI. (SD) | 0.97 (0.02) | 0.99 (0.01) | 0.96 (0.020) | 0.97 (0.02) | 0.98 (0.03) | 0.99 (0.01) | * ° |
ΔV (%). (SD) | −4.66 (5.16) | −8.68 (6.59) | −4.16 (5.43) | 0.14 (3.36) | −1.24 (3.51) | −0.52 (0.98) | * ° |
Δx (mm). (SD) | 0.70 (0.67) | 0.40 (0.55) | 0.88 (1.43) | 1.48 (2.22) | 0.60 (0.42) | 0.00 (0.00) | |
Δy (mm). (SD) | 2.46 (2.59) | 2.46 (2.59) | 2.24 (2.50) | 1.30 (0.67) | 0.90 (0.96) | 0.00 (0.00) | ^ |
Δz (mm). (SD) | 7.50 (7.07) | 7.50 (7.07) | 10.00 (7.91) | 1.88 (3.75) | 1.88 (3.75) | 0.00 (0.00) | |
Esophagus
| |||||||
DSC. (SD) | 0.68 (0.08) | 0.67 (0.08) | 0.62 (0.03) | 0.69 (0.08) | 0.83 (0.12) | 0.76 (0.02) | # ° |
Sensitivity. (SD) | 0.78 (0.08) | 0.69 (0.10) | 0.73 (0.09) | 0.79 (0.08) | 0.80 (0.13) | 0.84 (0.07) | * # |
IncI. (SD) | 0.61 (0.13) | 0.67 (0.13) | 0.54 (0.07) | 0.62 (0.13) | 0.86 (0.12) | 0.70 (0.06) | * ° + = |
ΔV (%). (SD) | 32.92 (31.51) | 6.80 (25.74) | 37.98 (28.67) | 33.46 (32.52) | −5.98 (11.80) | 21.22 (17.13) | * ° + = |
Δx (mm). (SD) | 3.82 (2.46) | 2.36 (1.84) | 2.92 (2.49) | 3.34 (1.87) | 1.30 (0.76) | 1.40 (0.55) | ^ |
Δy (mm). (SD) | 2.74 (2.78) | 2.54 (2.84) | 2.26 (2.33) | 2.74 (2.77) | 1.18 (1.81) | 2.16 (2.92) | |
Δz (mm). (SD) | 7.50 (7.29) | 8.00 (6.94) | 7.00 (6.47) | 7.50 (7.29) | 5.00 (7.32) | 5.50 (7.37) | + |
Heart
| |||||||
DSC. (SD) | 0.88 (0.03) | 0.87 (0.05) | 0.88 (0.05) | 0.90 (0.01) | 0.94 (0.01) | 0.95 (0.01) | + ^ |
Sensitivity. (SD) | 0.86 (0.09) | 0.82 (0.10) | 0.86 (0.10) | 0.89 (0.06) | 0.93 (0.03) | 0.94 (0.02) | * ° ^ |
IncI. (SD) | 0.91 (0.04) | 0.93 (0.04) | 0.90 (0.03) | 0.91 (0.05) | 0.96 (0.04) | 0.96 (0.02) | * ^ |
ΔV (%). (SD) | −4.48 (14.19) | −11.40 (13.81) | −4.58 (14.07) | −1.50 (11.80) | −2.30 (6.80) | −2.02 (4.08) | * ° |
Δx (mm). (SD) | 1.26 (1.04) | 1.18 (0.80) | 1.20 (0.45) | 1.38 (0.99) | 0.80 (0.45) | 1.58 (0.93) | |
Δy (mm). (SD) | 1.78 (1.22) | 1.58 (1.26) | 1.76 (1.48) | 1.86 (1.25) | 1.08 (1.10) | 1.28 (0.72) | |
Δz (mm). (SD) | 2.50 (1.77) | 3.50 (2.85) | 3.50 (2.24) | 3.00 (2.09) | 1.50 (1.37) | 2.00 (2.09) | |
Intestine
| |||||||
DSC. (SD) | 0.77 (0.13) | 0.74 (0.15) | 0.77 (0.13) | 0.87 (0.03) | 0.93 (0.04) | 0.93 (0.02) | + ^ |
Sensitivity. (SD) | 0.75 (0.21) | 0.68 (0.21) | 0.74 (0.21) | 0.90 (0.05) | 0.90 (0.06) | 0.95 (0.01) | * ° ^ |
IncI. (SD) | 0.85 (0.09) | 0.86 (0.08) | 0.84 (0.10) | 0.86 (0.07) | 0.97 (0.03) | 0.92 (0.04) | * ° + ^ = |
ΔV (%). (SD) | −9.54 (30.30) | −19.36 (29.33) | −9.7 (31.47) | 5.46 (14.22) | −7.48 (5.73) | 2.98 (5.13) | * ° + = |
Δx (mm). (SD) | 2.94 (1.36) | 4.90 (4.77) | 4.52 (5.51) | 2.08 (1.21) | 1.58 (1.05) | 1.08 (1.10) | ^ |
Δy (mm). (SD) | 4.12 (4.23) | 4.20 (4.05) | 4.70 (3.83) | 1.86 (1.55) | 1.48 (0.67) | 1.86 (2.54) | |
Δz (mm). (SD) | 11.50 (8.40) | 12.00 (7.37) | 12.00 (7.16) | 3.00 (4.11) | 0.00 (0.00) | 1.00 (1.37) | |
Liver
| |||||||
DSC. (SD) | 0.93 (0.02) | 0.93 (0.03) | 0.90 (0.01) | 0.93 (0.03) | 0.97 (0.02) | 0.95 (0.02) | # ° + |
Sensitivity. (SD) | 0.92 (0.02) | 0.90 (0.03) | 0.92 (0.03) | 0.93 (0.03) | 0.95 (0.03) | 0.96 (0.02) | ^ |
IncI. (SD) | 0.93 (0.03) | 0.95 (0.04) | 0.88 (0.02) | 0.93 (0.03) | 0.98 (0.02) | 0.94 (0.03) | * # ° + = |
ΔV (%). (SD) | −0.80 (2.10) | −5.08 (2.16) | 5.44 (4.93) | 0.00 (2.29) | −2.96 (2.41) | 2.26 (4.28) | * ° + = |
Δx (mm). (SD) | 3.24 (2.53) | 2.64 (1.81) | 3.80 (2.26) | 2.16 (1.90) | 0.60 (0.65) | 0.70 (0.45) | |
Δy (mm). (SD) | 1.28 (1.11) | 1.56 (1.09) | 1.38 (0.70) | 1.18 (1.27) | 0.60 (0.55) | 1.00 (0.70) | |
Δz (mm). (SD) | 1.50 (2.24) | 3.50 (2.85) | 4.50 (3.26) | 2.50 (1.77) | 1.00 (1.37) | 1.00 (1.37) | |
Kidney left
| |||||||
DSC. (SD) | 0.89 (0.02) | 0.87 (0.03) | 0.81 (0.06) | 0.91 (0.01) | 0.95 (0.02) | 0.92 (0.02) | * # ° = |
Sensitivity. (SD) | 0.88 (0.05) | 0.84 (0.06) | 0.81 (0.12) | 0.93 (0.02) | 0.92 (0.03) | 0.91 (0.02) | * # |
IncI. (SD) | 0.89 (0.02) | 0.90 (0.03) | 0.82 (0.04) | 0.88 (0.02) | 0.98 (0.03) | 0.93 (0.04) | * # ° + = |
ΔV (%). (SD) | −0.98 (7.21) | −7.40 (8.71) | −1.40 (15.64) | 4.90 (4.36) | −6.08 (3.41) | −1.10 (5.61) | * + |
Δx (mm). (SD) | 0.90 (0.74) | 1.10 (0.65) | 1.30 (0.57) | 0.80 (0.57) | 0.50 (0.50) | 1.00 (0.79) | |
Δy (mm). (SD) | 0.60 (0.42) | 0.70 (0.84) | 1.18 (1.11) | 0.40 (0.22) | 0.20 (0.27) | 0.50 (0.36) | |
Δz (mm). (SD) | 2.00 (1.12) | 4.00 (2.85) | 6.50 (5.18) | 1.50 (1.37) | 0.00 (0.00) | 0.00 (0.00) | |
Kidney right
| |||||||
DSC. (SD) | 0.89 (0.02) | 0.86 (0.04) | 0.83 (0.05) | 0.91 (0.02) | 0.95 (0.02) | 0.93 (0.01) | # |
Sensitivity. (SD) | 0.88 (0.04) | 0.83 (0.06) | 0.81 (0.10) | 0.93 (0.03) | 0.91 (0.03) | 0.92 (0.02) | # |
IncI. (SD) | 0.90 (0.05) | 0.91 (0.05) | 0.86 (0.09) | 0.89 (0.05) | 0.99 (0.02) | 0.94 (0.02) | # ° + ^ = |
ΔV (%). (SD) | −1.92 (9.47) | −8.68 (8.81) | −4.30 (17.24) | 4.28 (7.74) | −7.72 (1.43) | −2.46 (3.08) | + ^ = |
Δx (mm). (SD) | 1.46 (1.13) | 1.06 (1.24) | 1.10 (0.74) | 0.80 (0.76) | 0.60 (0.42) | 0.50 (0.71) | |
Δy (mm). (SD) | 0.60 (0.55) | 0.70 (0.45) | 1.08 (1.70) | 0.60 (0.55) | 0.50 (0.35) | 0.80 (0.57) | |
Δz (mm). (SD) | 3.50 (2.85) | 3.00 (4.11) | 5.00 (6.37) | 1.00 (1.37) | 0.50 (1.12) | 0.50 (1.12) | |
Spinal cord
| |||||||
DSC. (SD) | 0.71 (0.07) | 0.69 (0.08) | 0.74 (0.06) | 0.73 (0.04) | 0.83 (0.02) | 0.86 (0.05) | # ° ^ |
Sensitivity. (SD) | 0.65 (0.15) | 0.61 (0.16) | 0.74 (0.16) | 0.69 (0.12) | 0.72 (0.18) | 0.85 (0.11) | * # ° ^ |
IncI. (SD) | 0.82 (0.15) | 0.85 (0.13) | 0.78 (0.12) | 0.83 (0.14) | 1.00 (0.00) | 0.88 (0.06) | * # ° + = |
ΔV (%). (SD) | −15.72 (32.61) | −24.9 (31.50) | −0.72 (34.59) | −12.86 (31.11) | −27.76 (18.01) | −3.02 (16.70) | * # ° = |
Δx (mm). (SD) | 1.00 (0.61) | 0.80 (0.27) | 0.40 (0.42) | 1.00 (0.61) | 0.30 (0.45) | 0.40 (0.65) | |
Δy (mm). (SD) | 4.70 (5.93) | 4.40 (4.90) | 4.02 (4.06) | 4.70 (5.93) | 0.80 (0.67) | 0.2 (0.27) | |
Δz (mm). (SD) | 22.00 (23.21) | 22.00 (22.87) | 21.50 (21.84) | 9.00 (8.94) | 3.00 (4.11) | 1.00 (2.24) | |
Spleen
| |||||||
DSC. (SD) | 0.92 (0.01) | 0.90 (0.03) | 0.84 (0.04) | 0.93 (0.01) | 0.95 (0.02) | 0.94 (0.01) | # ° = |
Sensitivity. (SD) | 0.90 (0.00) | 0.86 (0.03) | 0.88 (0.02) | 0.92 (0.01) | 0.92 (0.02) | 0.94 (0.01) | ^ |
IncI. (SD) | 0.93 (0.02) | 0.96 (0.03) | 0.80 (0.06) | 0.94 (0.01) | 0.99 (0.02) | 0.93(0.03) | * # ° + |
ΔV (%). (SD) | −3.85 (2.04) | −10.38 (2.89) | 9.90 (10.45) | −3.00 (1.12) | −6.73 (1.16) | 1.18 (4.04) | * + |
Δx (mm). (SD) | 0.75 (0.65) | 0.88 (0.48) | 1.00 (0.41) | 1.48 (0.78) | 0.50 (0.00) | 0.75 (0.64) | |
Δy (mm). (SD) | 2.58 (2.89) | 2.95 (2.61) | 3.58 (3.49) | 1.73 (1.51) | 1.00 (0.58) | 1.75 (0.29) | |
Δz (mm). (SD) | 2.50 (2.04) | 1.88 (2.93) | 3.75 (2.23) | 1.25 (1.44) | 0.00 (0.00) | 1.88 (2.39) |