The popularity of immediate loading implants has increased considerably among patients and dentists [
1]. The advantages of immediate loading are to reduce the number of interventions and time of prosthetic [
2]. Furthermore, the success of immediate loading is related to the primary implant stability and loading control [
3]. In fact, primary stability has always been considered fundamental to osseointegration. To facilitate the immediate loading protocol, the stability of the implant at the time of placement is essential [
4], and implant surface modifications have a significant role in measuring the success of osseointegration. The primary implant stability at placement is the mechanical phenomenon related to the quality and quantity of the bone at the recipient site, the type and design of the implant used. These parameters can be better controlled with a one-pieiece implant [
4]. In fact, although two-piece implants have shown great success for a long time, the two stages of surgical procedures, the infiltration of bacteria in the microgap between abutment and implant, and the screw fracture after loading, are considered complications that could be overcome by the use of one-piece implants [
5]. In addition, the one-piece implant allows a minimally invasive flapless surgery which is very well accepted by patients [
6]. The immediate prosthetic of a one-piece system allows for better tissue healing [
7], better adhesion of the gingival mucosa to form a collar which is healthy and adherent to the implant, and avoiding a second surgical procedure [
8]. The prosthetic procedure of a one-piece implant enables the physiology of the natural tooth. The one-piece implant enables a borderline preparation following the contour of the gingival margin leading to a better preservation of mucous seal [
9]. One-piece immediate loading implants have a survival rate similar to delayed loading implants [
10]. Since immediate loading of one-piece implants has become a widely used procedure for rehabilitation of partially edentulous patients, we decided to perform a retrospective study on one-piece implants inserted in partially edentulous mandibles.