Erschienen in:
Open Access
01.12.2015 | Meeting abstract
Efficacy of SGLT2 inhibitors in glycemic control, weight loss and blood pressure reduction: a systematic review and meta-analysis
verfasst von:
Lana Catani Pinto, Dimitris Varvaki Rados, Luciana Reck Remonti, Caroline Kaercher Kramer, Cristiane Bauermann Leitao, Jorge Luiz Gross
Erschienen in:
Diabetology & Metabolic Syndrome
|
Sonderheft 1/2015
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Excerpt
Sodium–glucose cotransporter 2 inhibitors (SGLT2i) are a novel antidiabetic class that inhibits glucose reabsorption and produce glycosuria. These medications are being increasingly used as dual therapy with metformin for type 2 diabetes (T2D) treatment, due to their beneficial effect on weight and blood pressure. Three agents are approved for clinical use and they may differ on potency due to inhibition of only renal or both renal and bowel glucose transportation. …