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Arthritis Research & Therapy

Erschienen in:

01.04.2006 | Review

Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow

verfasst von: Jean-Pierre Pelletier, Johanne Martel-Pelletier, Jean-Pierre Raynauld

Erschienen in: Arthritis Research & Therapy | Ausgabe 2/2006

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Abstract

Osteoarthritis (OA), the most common of all arthritic conditions, is a social and financial burden to all nations. The most recent research has significantly advanced our understanding of the cause of OA and risk factors associated with it. These findings have provided useful information that has helped in the daily management of patients with OA. Some preventative measures and a number of therapeutic agents and drugs are available, which may help to reduce the progression of OA in certain patients. Moreover, the most recent progress in research has significantly enhanced our knowledge of the factors involved in the development of the disease and of the mechanisms responsible for its progression. This has allowed identification of several new therapeutic targets in a number of pathophysiological pathways. Consequently, the field is opening up to a new era in which drugs and agents that can specifically block important mechanisms responsible for the structural changes that occur in OA can be brought into development and eventually into clinical trials.

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Titel: Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow
verfasst von: Jean-Pierre Pelletier
Johanne Martel-Pelletier
Jean-Pierre Raynauld
Publikationsdatum: 01.04.2006
Verlag: BioMed Central
Erschienen in: Arthritis Research & Therapy / Ausgabe 2/2006
Elektronische ISSN: 1478-6362
DOI: https://doi.org/10.1186/ar1932

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