Skip to main content
Erschienen in: Breast Cancer Research 3/2010

01.06.2010 | Editorial

Managing bone mineral density with oral bisphosphonate therapy in women with breast cancer receiving adjuvant aromatase inhibition

verfasst von: Catherine Van Poznak

Erschienen in: Breast Cancer Research | Ausgabe 3/2010

Einloggen, um Zugang zu erhalten

Abstract

The use of adjuvant aromatase inhibitors is associated with an increased risk of osteoporosis and fractures. The oral bisphosphonate, risedronate - dosed as the US Food and Drug Administration approved for the treatment or prevention of postmenopausal osteoporosis - appears to mitigate bone loss associated with 2 years of adjuvant anastrozole in women with early-stage breast cancer.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Markopoulos C, Tzoracoleftherakis E, Polychronis A, Venizelos B, Dafni U, Xepapadakis G, Papadiamantis J, Zobolas V, Misitzis J, Kalogerakos K, Sarantopoulou A, Siasos N, Koukouras D, Antonopoulou Z, Lazarou S, Gogas H: Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial. Breast Cancer Res. 2010, 12: R24-10.1186/bcr2565.CrossRefPubMedPubMedCentral Markopoulos C, Tzoracoleftherakis E, Polychronis A, Venizelos B, Dafni U, Xepapadakis G, Papadiamantis J, Zobolas V, Misitzis J, Kalogerakos K, Sarantopoulou A, Siasos N, Koukouras D, Antonopoulou Z, Lazarou S, Gogas H: Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial. Breast Cancer Res. 2010, 12: R24-10.1186/bcr2565.CrossRefPubMedPubMedCentral
2.
Zurück zum Zitat Lester JE, Dodwell D, Purohit OP, Gutcher SA, Ellis SP, Thorpe R, Horsman JM, Brown JE, Hannon RA, Coleman RE: Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer. Clin Cancer Res. 2008, 14: 6336-6342. 10.1158/1078-0432.CCR-07-5101.CrossRefPubMed Lester JE, Dodwell D, Purohit OP, Gutcher SA, Ellis SP, Thorpe R, Horsman JM, Brown JE, Hannon RA, Coleman RE: Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer. Clin Cancer Res. 2008, 14: 6336-6342. 10.1158/1078-0432.CCR-07-5101.CrossRefPubMed
3.
Zurück zum Zitat Van Poznak C, Hannon RA, Mackey JR, Campone M, Apffelstaedt JP, Clack G, Barlow D, Makris A, Eastell R: Prevention of aromatase inhibitor-induced bone loss using risedronate: the SABRE trial. J Clin Oncol. 2010, 28: 967-975. 10.1200/JCO.2009.24.5902.CrossRefPubMed Van Poznak C, Hannon RA, Mackey JR, Campone M, Apffelstaedt JP, Clack G, Barlow D, Makris A, Eastell R: Prevention of aromatase inhibitor-induced bone loss using risedronate: the SABRE trial. J Clin Oncol. 2010, 28: 967-975. 10.1200/JCO.2009.24.5902.CrossRefPubMed
4.
Zurück zum Zitat Chapurlat RD, Delmas PD: Drug Insight: bisphosphonates for postmenopausal osteoporosis. Nat Clin Pract Endocrinol Metab. 2006, 2: 211-219. 10.1038/ncpendmet0121.CrossRefPubMed Chapurlat RD, Delmas PD: Drug Insight: bisphosphonates for postmenopausal osteoporosis. Nat Clin Pract Endocrinol Metab. 2006, 2: 211-219. 10.1038/ncpendmet0121.CrossRefPubMed
5.
Zurück zum Zitat Penning-van Beest FJA, Erkens JA, Olson M, Herings RM: Determinants of non-compliance with bisphosphonates in women with postmenopausal osteoporosis. Curr Med Res Opin. 2008, 24: 1337-1344. 10.1185/030079908X297358.CrossRefPubMed Penning-van Beest FJA, Erkens JA, Olson M, Herings RM: Determinants of non-compliance with bisphosphonates in women with postmenopausal osteoporosis. Curr Med Res Opin. 2008, 24: 1337-1344. 10.1185/030079908X297358.CrossRefPubMed
6.
Zurück zum Zitat Cramer JA, Lynch NO, Gaudin A-F, Walker M, Cowell W: The effect of dosing frequency on compliance and persistence with bisphosphonate therapy in postmenopausal women: a comparison of studies in the United States, the United Kingdom, and France. Clin Ther. 2006, 28: 1686-1694. 10.1016/j.clinthera.2006.10.013.CrossRefPubMed Cramer JA, Lynch NO, Gaudin A-F, Walker M, Cowell W: The effect of dosing frequency on compliance and persistence with bisphosphonate therapy in postmenopausal women: a comparison of studies in the United States, the United Kingdom, and France. Clin Ther. 2006, 28: 1686-1694. 10.1016/j.clinthera.2006.10.013.CrossRefPubMed
7.
Zurück zum Zitat Brufsky AM, Bosserman LD, Caradonna RR, Haley BB, Jones CM, Moore HC, Jin L, Warsi GM, Ericson SG, Perez EA: Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results. Clin Breast Cancer. 2009, 9: 77-85. 10.3816/CBC.2009.n.015.CrossRefPubMed Brufsky AM, Bosserman LD, Caradonna RR, Haley BB, Jones CM, Moore HC, Jin L, Warsi GM, Ericson SG, Perez EA: Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results. Clin Breast Cancer. 2009, 9: 77-85. 10.3816/CBC.2009.n.015.CrossRefPubMed
8.
Zurück zum Zitat Gnant M, Mlineritsch B, Lushin-Ebengreuth G, Kainberger F, Kässmann H, Piswanger-Sölkner JC, Seifert M, Ploner F, Menzel C, Dubsky P, Fitzal F, Bjelic-Radisic V, Steger G, Greil R, Marth C, Kubista E, Samonigg H, Wohlmuth P, Mittlböck M, Jakesz R, Austrian Breast and Colorectal Cancer Study Group (ABCSG): Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol. 2008, 9: 840-849. 10.1016/S1470-2045(08)70204-3.CrossRefPubMed Gnant M, Mlineritsch B, Lushin-Ebengreuth G, Kainberger F, Kässmann H, Piswanger-Sölkner JC, Seifert M, Ploner F, Menzel C, Dubsky P, Fitzal F, Bjelic-Radisic V, Steger G, Greil R, Marth C, Kubista E, Samonigg H, Wohlmuth P, Mittlböck M, Jakesz R, Austrian Breast and Colorectal Cancer Study Group (ABCSG): Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol. 2008, 9: 840-849. 10.1016/S1470-2045(08)70204-3.CrossRefPubMed
9.
Zurück zum Zitat Hines SL, Sloan JA, Atherton PJ, Perez EA, Dakhil SR, Johnson DB, Reddy PS, Dalton RJ, Mattar BI, Loprinzi CL: Zoledronic acid for treatment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy. Breast. 2010, 19: 92-96. 10.1016/j.breast.2009.12.001.CrossRefPubMedPubMedCentral Hines SL, Sloan JA, Atherton PJ, Perez EA, Dakhil SR, Johnson DB, Reddy PS, Dalton RJ, Mattar BI, Loprinzi CL: Zoledronic acid for treatment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy. Breast. 2010, 19: 92-96. 10.1016/j.breast.2009.12.001.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Brown JE, Ellis SP, Lester JE, Gutcher S, Khanna T, Purohit OP, McCloskey E, Coleman RE: Prolonged efficacy of a single dose of the bisphosphonate zoledronic acid. Clin Cancer Res. 2007, 13: 5406-5410. 10.1158/1078-0432.CCR-07-0247.CrossRefPubMed Brown JE, Ellis SP, Lester JE, Gutcher S, Khanna T, Purohit OP, McCloskey E, Coleman RE: Prolonged efficacy of a single dose of the bisphosphonate zoledronic acid. Clin Cancer Res. 2007, 13: 5406-5410. 10.1158/1078-0432.CCR-07-0247.CrossRefPubMed
11.
Zurück zum Zitat Saad F, Adachi JD, Brown JP, Canning LA, Gelmon KA, Josse RG, Pritchard KI: Cancer treatment-induced bone loss in breast and prostate cancer. J Clin Oncol. 2008, 26: 5465-5476. 10.1200/JCO.2008.18.4184.CrossRefPubMed Saad F, Adachi JD, Brown JP, Canning LA, Gelmon KA, Josse RG, Pritchard KI: Cancer treatment-induced bone loss in breast and prostate cancer. J Clin Oncol. 2008, 26: 5465-5476. 10.1200/JCO.2008.18.4184.CrossRefPubMed
12.
Zurück zum Zitat Hines SL, Mincey BA, Sloan JA, Thomas SP, Chottiner E, Loprinzi CL, Carlson MD, Atherton PJ, Salim M, Perez EA: Phase III randomized, placebocontrolled, double-blind trial of risedronate for the prevention of bone loss in premenopausal women undergoing chemotherapy for primary breast cancer, 2009. J Clin Oncol. 2009, 27: 1047-1053. 10.1200/JCO.2008.19.1783.CrossRefPubMed Hines SL, Mincey BA, Sloan JA, Thomas SP, Chottiner E, Loprinzi CL, Carlson MD, Atherton PJ, Salim M, Perez EA: Phase III randomized, placebocontrolled, double-blind trial of risedronate for the prevention of bone loss in premenopausal women undergoing chemotherapy for primary breast cancer, 2009. J Clin Oncol. 2009, 27: 1047-1053. 10.1200/JCO.2008.19.1783.CrossRefPubMed
Metadaten
Titel
Managing bone mineral density with oral bisphosphonate therapy in women with breast cancer receiving adjuvant aromatase inhibition
verfasst von
Catherine Van Poznak
Publikationsdatum
01.06.2010
Verlag
BioMed Central
Erschienen in
Breast Cancer Research / Ausgabe 3/2010
Elektronische ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr2584

Weitere Artikel der Ausgabe 3/2010

Breast Cancer Research 3/2010 Zur Ausgabe

Update Onkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.